Conceptual design of an airborne laser Doppler velocimeter system for studying wind fields associated with severe local storms

An airborne laser Doppler velocimeter was evaluated for diagnostics of the wind field associated with an isolated severe thunderstorm. Two scanning configurations were identified, one a long-range (out to 10-20 km) roughly horizontal plane mode intended to allow probing of the velocity field around the storm at the higher altitudes (4-10 km). The other is a shorter range (out to 1-3 km) mode in which a vertical or horizontal plane is scanned for velocity (and possibly turbulence), and is intended for diagnostics of the lower altitude region below the storm and in the out-flow region. It was concluded that aircraft flight velocities are high enough and severe storm lifetimes are long enough that a single airborne Doppler system, operating at a range of less than about 20 km, can view the storm area from two or more different aspects before the storm characteristics change appreciably

Vaccination of Cattle with the N Terminus of LppQ of Mycoplasma mycoides subsp. mycoides Results in Type III Immune Complex Disease upon Experimental Infection

Contagious bovine pleuropneumonia (CBPP) is a serious respiratory disease of cattle caused by Mycoplasma mycoides subsp. mycoides. Current vaccines against CBPP induce short-lived immunity and can cause severe postvaccine reactions. Previous studies have identified the N terminus of the transmembrane lipoprotein Q (LppQ-N') of M. mycoides subsp. mycoides as the major antigen and a possible virulence factor. We therefore immunized cattle with purified recombinant LppQ-N' formulated in Freund's adjuvant and challenged them with M. mycoides subsp. mycoides. Vaccinated animals showed a strong seroconversion to LppQ, but they exhibited significantly enhanced postchallenge glomerulonephritis compared to the placebo group (P = 0.021). Glomerulonephritis was characterized by features that suggested the development of antigen-antibody immune complexes. Clinical signs and gross pathological scores did not significantly differ between vaccinated and placebo groups. These findings reveal for the first time the pathogenesis of enhanced disease as a result of antibodies against LppQ during challenge and also argue against inclusion of LppQ-N' in a future subunit vaccine for CBPP

Tablet computers in assessing performance in a high stakes exam : opinion matters

The authors would like to thank Dr Craig brown, University of Aberdeen for assistance with data analysis.Peer reviewedPublisher PD

Spectrum of turbulent Kelvin-waves cascade in superfluid helium

To explain the observed decay of superfluid turbulence at very low temperature, it has been proposed that a cascade of Kelvin waves (analogous to the classical Kolmogorov cascade) transfers kinetic energy to length scales which are small enough that sound can be radiated away. We report results of numerical simulations of the interaction of quantized vortex filaments. We observe the development of the Kelvin-waves cascade, and compute the statistics of the curvature, the amplitude spectrum (which we compare with competing theories) and the fractal dimension.Comment: 32 pages, 22 figure

Ion-induced nucleation in polar one-component fluids

We present a Ginzburg-Landau theory of ion-induced nucleation in a gas phase of polar one-component fluids, where a liquid droplet grows with an ion at its center. By calculating the density profile around an ion, we show that the solvation free energy is larger in gas than in liquid at the same temperature on the coexistence curve. This difference much reduces the nucleation barrier in a metastable gas.Comment: 9 pagers, 9 figures, to be published in J. Chem. Phy

Ground state of a large number of particles on a frozen topography

Problems consisting in finding the ground state of particles interacting with a given potential constrained to move on a particular geometry are surprisingly difficult. Explicit solutions have been found for small numbers of particles by the use of numerical methods in some particular cases such as particles on a sphere and to a much lesser extent on a torus. In this paper we propose a general solution to the problem in the opposite limit of a very large number of particles M by expressing the energy as an expansion in M whose coefficients can be minimized by a geometrical ansatz. The solution is remarkably universal with respect to the geometry and the interaction potential. Explicit solutions for the sphere and the torus are provided. The paper concludes with several predictions that could be verified by further theoretical or numerical work.Comment: 9 pages, 9 figures, LaTeX fil

The functional integral with unconditional Wiener measure for anharmonic oscillator

In this article we propose the calculation of the unconditional Wiener measure functional integral with a term of the fourth order in the exponent by an alternative method as in the conventional perturbative approach. In contrast to the conventional perturbation theory, we expand into power series the term linear in the integration variable in the exponent. In such a case we can profit from the representation of the integral in question by the parabolic cylinder functions. We show that in such a case the series expansions are uniformly convergent and we find recurrence relations for the Wiener functional integral in the $N$ - dimensional approximation. In continuum limit we find that the generalized Gelfand - Yaglom differential equation with solution yields the desired functional integral (similarly as the standard Gelfand - Yaglom differential equation yields the functional integral for linear harmonic oscillator).Comment: Source file which we sent to journa