4,764 research outputs found
Magnetars and pulsars: a missing link
There is growing evidence that soft gamma-ray repeaters (SGRs) and anomalous
X-ray pulsars (AXPs) are isolated neutron stars with superstrong magnetic
fields, i.e., magnetars, marking them a distinguished species from the
conventional species of spindown-powered isolated neutron stars, i.e., radio
pulsars. The current arguments in favor of the magnetar interpretation of
SGR/AXP phenomenology will be outlined, and the two energy sources in
magnetars, i.e. a magnetic dissipation energy and a spindown energy, will be
reviewed. I will then discuss a missing link between magnetars and pulsars,
i.e., lack of the observational evidence of the spindown-powered behaviors in
known magnetars. Some recent theoretical efforts in studying such behaviors
will be reviewed along with some predictions testable in the near future.Comment: Invited talk at the Sixth Pacific Rim Conference on Stellar
Astrophysics, a tribute to Helmut A. Abt, July 11-17, 2002, Xi'an. To appear
in the proceedings (eds. K. S. Cheng, K. C. Leung & T. P. Li
Magnetar-like X-ray Bursts from an Anomalous X-ray Pulsar
Anomalous X-ray Pulsars (AXPs) are a class of rare X-ray pulsars whose energy
source has been perplexing for some 20 years. Unlike other, better understood
X-ray pulsars, AXPs cannot be powered by rotation or by accretion from a binary
companion, hence the designation ``anomalous.'' AXP rotational and radiative
properties are strikingly similar to those of another class of exotic objects,
the Soft Gamma Repeaters (SGRs). However, the defining property of SGRs, namely
their low-energy gamma-ray and X-ray bursts, have heretofore not been seen in
AXPs. SGRs are thought to be ``magnetars,'' young neutron stars powered by the
decay of an ultra-high magnetic field. The suggestion that AXPs are magnetars
has been controversial. Here we report the discovery, from the direction of AXP
1E 1048-5937, of two X-ray bursts that have many properties similar to those of
SGR bursts. These events imply a close relationship between AXPs and SGRs, with
both being magnetars.Comment: 14 pages, 2 figures, accepted for publication in Nature. Note: The
content of this paper is embargoed until 1900 hrs London time / 1400 US
Eastern Time on Sept 1
Intestinal transplantation in composite visceral grafts or alone
Under FK 506-based immunosuppression, the entire cadaver small bowel except for a few proximal and distal centimeters was translated to 17 randomly matched patients, of whom two had antigraft cytotoxic antibodies (positive cross-match). Eight patients received the intestine only, eight had intestine in continuity with the liver, and one received a full multivisceral graft that included the liver, stomach, and pancreas. One liver-intestine recipient died after an intestinal anastomotic leak, sepsis, and graft- versus-host disease. The other 16 patients are alive after 1 to 23 months, in one case after chronic rejection, graft removal, and retransplantation. Twelve of the patients have been liberated from total parenteral nutrition, including all whose transplantation was 2 months or longer ago. The grafts have supported good nutrition, and in children, have allowed growth and weight gain. Management of these patients has been difficult and often complicated, but the end result has been satisfactory in most cases, justifying further clinical trials. The convalescence of the eight patients receiving intestine only has been faster and more trouble free than after liver-intestine or multivisceral transplantation, with no greater difficulty in the control of rejection
Intestinal transplantation in composite visceral grafts or alone
Under FK 506-based immunosuppression, the entire cadaver small bowel except for a few proximal and distal centimeters was translated to 17 randomly matched patients, of whom two had antigraft cytotoxic antibodies (positive cross-match). Eight patients received the intestine only, eight had intestine in continuity with the liver, and one received a full multivisceral graft that included the liver, stomach, and pancreas. One liver-intestine recipient died after an intestinal anastomotic leak, sepsis, and graft- versus-host disease. The other 16 patients are alive after 1 to 23 months, in one case after chronic rejection, graft removal, and retransplantation. Twelve of the patients have been liberated from total parenteral nutrition, including all whose transplantation was 2 months or longer ago. The grafts have supported good nutrition, and in children, have allowed growth and weight gain. Management of these patients has been difficult and often complicated, but the end result has been satisfactory in most cases, justifying further clinical trials. The convalescence of the eight patients receiving intestine only has been faster and more trouble free than after liver-intestine or multivisceral transplantation, with no greater difficulty in the control of rejection
Strong and Tunable Nonlinear Optomechanical Coupling in a Low-Loss System
A major goal in optomechanics is to observe and control quantum behavior in a
system consisting of a mechanical resonator coupled to an optical cavity. Work
towards this goal has focused on increasing the strength of the coupling
between the mechanical and optical degrees of freedom; however, the form of
this coupling is crucial in determining which phenomena can be observed in such
a system. Here we demonstrate that avoided crossings in the spectrum of an
optical cavity containing a flexible dielectric membrane allow us to realize
several different forms of the optomechanical coupling. These include cavity
detunings that are (to lowest order) linear, quadratic, or quartic in the
membrane's displacement, and a cavity finesse that is linear in (or independent
of) the membrane's displacement. All these couplings are realized in a single
device with extremely low optical loss and can be tuned over a wide range in
situ; in particular, we find that the quadratic coupling can be increased three
orders of magnitude beyond previous devices. As a result of these advances, the
device presented here should be capable of demonstrating the quantization of
the membrane's mechanical energy.Comment: 12 pages, 4 figures, 1 tabl
Links between traumatic brain injury and ballistic pressure waves originating in the thoracic cavity and extremities
Identifying patients at risk of traumatic brain injury (TBI) is important
because research suggests prophylactic treatments to reduce risk of long-term
sequelae. Blast pressure waves can cause TBI without penetrating wounds or
blunt force trauma. Similarly, bullet impacts distant from the brain can
produce pressure waves sufficient to cause mild to moderate TBI. The fluid
percussion model of TBI shows that pressure impulses of 15-30 psi cause mild to
moderate TBI in laboratory animals. In pigs and dogs, bullet impacts to the
thigh produce pressure waves in the brain of 18-45 psi and measurable injury to
neurons and neuroglia. Analyses of research in goats and epidemiological data
from shooting events involving humans show high correlations (r > 0.9) between
rapid incapacitation and pressure wave magnitude in the thoracic cavity. A case
study has documented epilepsy resulting from a pressure wave without the bullet
directly hitting the brain. Taken together, these results support the
hypothesis that bullet impacts distant from the brain produce pressure waves
that travel to the brain and can retain sufficient magnitude to induce brain
injury. The link to long-term sequelae could be investigated via
epidemiological studies of patients who were gunshot in the chest to determine
whether they experience elevated rates of epilepsy and other neurological
sequelae
Tetrahydrofurandiol Stimulation of Phospholipase A2, Lipoxygenase, and Cyclooxygenase Gene Expression and MCF-7 Human Breast Cancer Cell Proliferation
Influences on clinical decision-making during a community placement – reflections of a student nurse
The decision-making process in nursing is complex. High quality care is dependent
on good clinical judgement and decision-making. Nurses need to be able to justify
and defend their clinical decision-making. In this article, the author, a third-year
nursing student reflects on an incident from a community placement involving a
collaborative, clinical decision. Carper’s (1978) four fundamental patterns of knowing
are used to analyse the decision-making process. It is shown that influences on
decision-making include prior knowledge and expertise, law and accountability and
ethical principles such as respect for autonomy and beneficence. Good
communication, interpersonal skills and a person-centred approach have a bearing
on decision-making. It is argued that intuitio
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