The credibility of health economic models for health policy decision-making: the case of population screening for abdominal aortic aneurysm

<i>Objectives</i>: To review health economic models of population screening for abdominal aortic aneurysm (AAA) among elderly males and assess their credibility for informing decision-making. <i>Methods</i>: A literature review identified health economic models of ultrasound screening for AAA. For each model focussing on population screening in elderly males, model structure and input parameter values were critically appraised using published good practice guidelines for decision analytic models. <i>Results</i>: Twelve models published between 1989 and 2003 were identified. Converting costs to a common currency and base year, substantial variability in cost-effectiveness results were revealed. Appraisals carried out for the nine models focusing on population screening showed differences in their complexity, with the simpler models generating results most favourable to screening. Eight of the nine models incorporated two or more simplifying structural assumptions favouring screening; uncertainty surrounding these assumptions was not investigated by any model. Quality assessments on a small number of parameters revealed input values varied between models, methods used to identify and incorporate input data were often not described, and few sensitivity analyses were reported. <i>Conclusions</i>: Large variation exists in the cost-effectiveness results generated by AAA screening models. The substantial number of factors potentially contributing to such disparities means that reconciliation of model results is impossible. In addition, poor reporting of methods makes it difficult to identify the most plausible and thus most useful model of those developed

A Normative Theory of the Information Society

Alistair S. Duff has been writing interesting works about social conceptualizations of the information society since the mid-1990s. His earlier works have examined the origins of the information society paradigm, surveyed the pre-2001 research literature related to the information society, and discussed connections between the information society and social engineering, and in 2004 he explored the need for normative analysis in information policy. One can easily trace Duff’s progress toward the presently reviewed book;the aforementioned themes of the history of the information society, social engineering,and the normative attributes of information policy are the scaffolding used to support the Rawls-Tawney approach to evaluating information policy that is the centerpiece of this new monograph

La Importancia de la Teoria en el Ambito de la Biblioteconomia

Publicaciones recientes han reconocido la necesidad de más teoría en el campo de la bibliotecología y ciencias de la información; sin embargo ha habido muy poco para fomentar la construcción de teorías u ofrecer orientación en cómo se crea la teoría de la información. Este artículo provee un ejemplo de como se puede utilizar una revisión contemplativa de la investigación existente y de la literatura para desarrollar un modelo teórico de acceso a la información, con el propósito de demostrar como otros pueden tomar pasos similares para mejorar la teoría en el campo de la bibliotecología y ciencias de la información

Spatiotemporal variability in the O-18-salinity relationship of seawater across the tropical Pacific Ocean

The relationship between salinity and the stable oxygen isotope ratio of seawater (δ18Osw) is of utmost importance to the quantitative reconstruction of past changes in salinity from δ18O values of marine carbonates. This relationship is often considered to be uniform across water masses, but the constancy of the δ18Osw-salinity relationship across space and time remains uncertain, as δ18Osw responds to varying atmospheric vapor sources and pathways, while salinity does not. Here we present new δ18Osw-salinity data from sites spanning the tropical Pacific Ocean. New data from Palau, Papua New Guinea, Kiritimati, and Galápagos show slopes ranging from 0.09 ‰/psu in the Galápagos to 0.32‰/psu in Palau. The slope of the δ18Osw-salinity relationship is higher in the western tropical Pacific versus the eastern tropical Pacific in observations and in two isotope-enabled climate model simulations. A comparison of δ18Osw-salinity relationships derived from short-term spatial surveys and multiyear time series at Papua New Guinea and Galápagos suggests spatial relationships can be substituted for temporal relationships at these sites, at least within the time period of the investigation. However, the δ18Osw-salinity relationship varied temporally at Palau, likely in response to water mass changes associated with interannual El Niño–Southern Oscillation (ENSO) variability, suggesting nonstationarity in this local δ18Osw-salinity relationship. Applying local δ18Osw-salinity relationships in a coral δ18O forward model shows that using a constant, basinwide δ18Osw-salinity slope can both overestimate and underestimate the contribution of δ18Osw to carbonate δ18O variance at individual sites in the western tropical Pacific.We are grateful for the dedicated water samplers who enabled this research: Lori J. Bell and Gerda Ucharm of the Coral Reef Research Foundation, Palau; Rosa Maritza Motoche Gonzalez and the Fuerza Aerea Ecuatoriana, Santa Cruz, Galapagos, Ecuador; Taonateiti Kabiri and the students of Tennessee Primary School, London, Kiritimati; and the Manus Weather Observers, U.S. Department of Energy ARM Climate Research Facility, Manus, Papua New Guinea. We would like to thank the Galapagos National Park, the Kiritimati Ministry of Environment Lands and Agricultural Development for sample permits, and the Charles Darwin Research Station for logistical support. Funding sources for this work includes NSF-AGS-PF 1049664 to J.L.C., NSF P2C2-1203785 to K.M.C., J.L.C., and D.N. This research was also supported by the Office of Biological and Environment Research of the U.S. Department of Energy as part of the Atmospheric Radiation Measurement Climate Research Facility. Isotope data are available as supporting information associated with the manuscript. (1049664 - NSF-AGS-PF; P2C2-1203785 - NSF; Office of Biological and Environment Research of the U.S. Department of Energy as part of the Atmospheric Radiation Measurement Climate Research Facility

ICT Women Professionals\u27 Perceptions of Workplace Ethical Problems: A Quantitative Survey

Which ethical problems are most frequently experienced by ICT women professionals? Which ethical problems experienced by ICT women professionals are of most concern to them as individuals? A quantitative survey of 2,315 Australian ICT professionals of whom 15.4 percent were females revealed that the top 15 most frequently faced ethical problems that the females identified were nearly identical to those identified by males. Of these 15 problems, five were judged to affect females personally. These are overworking staff, blaming others for own mistakes, bullying, unprofessional behavior, and discrimination. Of these five problems, gender only predicted three problems that affect females personally, namely overworking staff, bullying, and discrimination, which women also believed occur more frequently than other problems. Compared to males, a higher percentage of females who selected overworking staff, bullying, and discrimination believed unethical behavior either occurs occasionally or frequently. More importantly, a higher proportion of females compared to males (especially managers and consultants) witnessed or experienced staff being overworked in their workplaces. Similarly, a higher proportion of females compared to males (especially managers and consultants) witnessed or experienced bullying in their workplaces. Finally, a higher proportion of females compared to males (especially man- agers and consultants) witnessed or experienced discrimination in their workplaces. The fact that female consultants and mangers selected these problems as of most concern to them may suggest that the experienced women professionals have a greater concern about these problems than women in junior roles. Regardless, these results are both surprising and concerning and therefore deserving of attention in a future study

Exploring Barriers to ICT Use by Middle Class Indian Women

Nations have made great strides in providing physical access to digital technologies and educational opportunities, yet barriers still exist that prevent those who have strong physical and intellectual access to information and communication technology from taking full advantage of the information and opportunities the technology offers. Women in particular are affected by social barriers which may be quite subtle and are easily excluded from taking an active role in the information society. This study explores how Indian women incorporate information and communication technology (ICT) into their daily lives and what aidsor barriers they face in the process. This study contributes to an understanding of factors that lead to Indian women’s current use of ICT, reasons why Indian women choose to use ICT, and barriers to this usage

Differently Abled Staff Welcomed by Library Recruiters

The article focuses on the benefits of reading therapy for improving health and well being for people living with disability. Topics discussed include providing knowledge or skills to provide services or resources to people living with a disability; encouraging library employers to form job advertisement with diversity and disability in mind; and encouraging employment of the same

Boosting automatic event extraction from the literature using domain adaptation and coreference resolution

Motivation: In recent years, several biomedical event extraction (EE) systems have been developed. However, the nature of the annotated training corpora, as well as the training process itself, can limit the performance levels of the trained EE systems. In particular, most event-annotated corpora do not deal adequately with coreference. This impacts on the trained systems' ability to recognize biomedical entities, thus affecting their performance in extracting events accurately. Additionally, the fact that most EE systems are trained on a single annotated corpus further restricts their coverage