10,948 research outputs found
Supply Chain Managers and Risk Behavior: Testing the Sitkin and Pablo Model
The frequency of supply chain disruptions is increasing and the resulting costs amplify with the growth of supply chain density and complexity. Supply chain managers serve a pivotal role in ensuring continued firm competitiveness and success. Having the right person whose risk preferences, propensity to take risks, and history dealing with risks match the needs of the company is important. A foundational study performed by Sitkin and Pablo (1992) proposed a conceptual model focused on specific predictors of risk behavior from the individual, organizational, and problem-related perspectives. Questions still remain to the validity of the model given that it has not been fully tested. With the gaps in the current literature, the purpose of this study is to examine (1) does the Sitkin and Pablo (1992) model serve as a valid fit to measure supply chain manager’s propensity and perception of risk and (2) how does the managerial disruption perspective affects the risk perceptions/risk behavior relationship? The findings of the study will contribute to theoretical development through the expansion of the managerial disruption perspective on risk perceptions and through addressing the mediating relationship of risk propensity and risk perception on risk behaviors. Empirical testing is performed using a sample of supply chain managers with statistical analysis of the study results
Survey of instrumental programs in nine medium-sized towns within commuting distance from New York City
Thesis (M.M.E.)--Boston Universit
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Interpreting the Earth's time varying geopotential as observed from space and comparisons to global models of hydrologic transport
textMeasurements of temporal changes in Earthís gravitational field were measured
using six years of satellite laser ranging (SLR) to Lageos-1 and Lagoes-2 and the results
were compared to geophysical models of mass variability for the atmosphere, ocean, and
continental hydrology. Annual estimates of spherical harmonic gravity coefficients
(degree and order four expansion) derived from the SLR observations when compared to
combinations of the mass models had degree correlations that generally exceeded the
90% confidence limit and agreed to about the 1 mm level in terms of geoid height
anomaly.
The Gravity Recovery and Climate Experiment (GRACE) is measuring Earthís
gravitational field approximately every month at spatial scales of a few hundred
kilometers. In order to achieve smaller temporal and spatial scales, it is necessary to
account for the effects of short period, non-tidal, mass variability which was not
previously included in other gravity determinations. Orbital simulations of GRACE
showed that the highest degrees were impacted the most by unmodeled variability in the
atmosphere, oceans, and continental hydrology (a factor of ~20 increase in degree error
in the case of the atmosphere). The use of approximate models gave the greatest
reduction in aliasing error for the mid-degrees and higher; however, the lowest degrees
(~2-5) were dominated by the sensitivity of the GRACE processing system to systematic
error. GRACE data processing that used a combined atmosphere-ocean de-aliasing
(AOD) model showed improvement in the gravity estimates consistent with the
simulations: the shorter spatial wavelengths (higher degrees) were improved while the
longest spatial wavelengths (particularly important for time-variable gravity studies) were
relatively unaffected.
Monthly gravity solutions from GRACE resolved features on the order of 2-3 mm
geoid height anomaly when smoothed to 400-km spatial scales. Comparisons with the
Global Land Data Assimilation System (GLDAS) terrestrial water storage model
indicated a high degree of correlation up to spatial wavelengths of 600 km or larger; a
significant improvement over the spatial and temporal scales obtained with SLR
observations. However, temporal variability in the degree 2 coefficients, particularly the
zonal, seemed to be better resolved by SLR observations than by GRACE observations.Aerospace Engineering and Engineering Mechanic
Federal Advisory Council to the Arts, United States Arts Foundation: Hearings (August 1962): Speech 03
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Structural Neuroimaging of Anorexia Nervosa: Future Directions in the Quest for Mechanisms Underlying Dynamic Alterations.
Anorexia nervosa (AN) is a serious eating disorder characterized by self-starvation and extreme weight loss. Pseudoatrophic brain changes are often readily visible in individual brain scans, and AN may be a valuable model disorder to study structural neuroplasticity. Structural magnetic resonance imaging studies have found reduced gray matter volume and cortical thinning in acutely underweight patients to normalize following successful treatment. However, some well-controlled studies have found regionally greater gray matter and persistence of structural alterations following long-term recovery. Findings from diffusion tensor imaging studies of white matter integrity and connectivity are also inconsistent. Furthermore, despite the severity of AN, the number of existing structural neuroimaging studies is still relatively low, and our knowledge of the underlying cellular and molecular mechanisms for macrostructural brain changes is rudimentary. We critically review the current state of structural neuroimaging in AN and discuss the potential neurobiological basis of structural brain alterations in the disorder, highlighting impediments to progress, recent developments, and promising future directions. In particular, we argue for the utility of more standardized data collection, adopting a connectomics approach to understanding brain network architecture, employing advanced magnetic resonance imaging methods that quantify biomarkers of brain tissue microstructure, integrating data from multiple imaging modalities, strategic longitudinal observation during weight restoration, and large-scale data pooling. Our overarching objective is to motivate carefully controlled research of brain structure in eating disorders, which will ultimately help predict therapeutic response and improve treatment
Cloning of a Carcinoembryonic Antigen Gene Family Member Expressed in Leukocytes of Chronic Myeloid Leukemia Patients and Bone Marrow
The carcinoembryonic antigen (CEA) gene family belongs to the immunoglobulin superfamily and can be subdivided into the CEA and pregnancy-specific glycoprotein subgroups. The basic structure of the encoded proteins consists of, in addition to a leader, one IgV-like and 2, 3, or 6 IgC-like domains. These domains are followed by varying COOH-terminal regions responsible for secretion, transmembrane anchoring, or insertion into the membrane by a glycosyl phosphatidylinositol tail. Here we report on the characterization of CGM6, a new member of the CEA gene subgroup, by complementary DNA cloning. The deduced coding region comprises 349 amino acids and consists of a leader, one IgV-like, two IgC-like domains, and a hydrophobic region, which is replaced by a glycosyl phosphatidylinositol moiety in the mature protein. CGM6 transcripts were only found thus far in leukocytes of chronic myeloid leukemia patients, in normal bone marrow, and in marginal amounts in normal granulocytes. The CGM6 gene product might, therefore, represent a myeloid marker. Analyses of CGM6 protein-expressing HeLa transfectants with monoclonal antibodies strongly indicate that the CGM6 gene codes for the CEA family member NCA-95
Absorption-Fluctuation Theorem for Nuclear Reactions: Brink-Axel, Incomplete Fusion and All That
We discuss the connection between absorption, averages and fluctuations in
nuclear reactions. The fluctuations in the entrance channel result in the
compound nucleus, Hauser-Feshbach, cross section, the fluctuations in the
intermediate channels, result in modifications of multistep reaction cross
sections, while the fluctuations in the final channel result in hybrid cross
sections that can be used to describe incomplete fusion reactions. We discuss
the latter in details and comment on the validity of the assumptions used in
the develpoment of the Surrogate method. We also discuss the theory of
multistep reactions with regards to intermediate state fluctuations and the
energy dependence and non-locality of the intermediate channels optical
potentials.Comment: 9 pages. Contribution to the International Workshop on
Compound-Nuclear Reactions and Related Topics (CNR*2007), October 22-26,
2007, Fish Camp, California. To be published in AIP Proceedings (Editor Jutta
Escher
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