Towards Ideal Semantics for Analyzing Stream Reasoning

The rise of smart applications has drawn interest to logical reasoning over data streams. Recently, different query languages and stream processing/reasoning engines were proposed in different communities. However, due to a lack of theoretical foundations, the expressivity and semantics of these diverse approaches are given only informally. Towards clear specifications and means for analytic study, a formal framework is needed to define their semantics in precise terms. To this end, we present a first step towards an ideal semantics that allows for exact descriptions and comparisons of stream reasoning systems.Comment: International Workshop on Reactive Concepts in Knowledge Representation (ReactKnow 2014), co-located with the 21st European Conference on Artificial Intelligence (ECAI 2014). Proceedings of the International Workshop on Reactive Concepts in Knowledge Representation (ReactKnow 2014), pages 17-22, technical report, ISSN 1430-3701, Leipzig University, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-150562 2014,

Queering Disasters: Embodied Crises in Post-Harvey Houston

This project addresses how neoliberal expansion complicates disaster recovery for queer communities in an urban context looking specifically at how disasters, disease, and marginalization operate as interlocking systems of oppression for queer people in the aftermath of Hurricane Harvey in 2017. This research draws upon anthropological studies of disasters, urban studies, critical medical anthropology, and queer theory to employ a queer political ecology that combines understandings of disasters and diseases as socio-political and ecological phenomena with queerness as a set of culturally constructed vulnerabilities that carry embodied effects. Starting from the understanding that disasters more heavily impact groups that already face some form of social or economic marginalization, this project focuses on the Montrose, Houston’s most prominent queer neighborhood, as a community that has struggled with gentrification prior to Harvey as well as the impacts of the HIV/AIDS epidemic. In this context, this project explores how interrelated structural and environmental crises are exacerbated not only by Hurricane Harvey but by neoliberal social and economic policies during the disaster recovery process

Spearfishing-induced behavioral changes of an unharvested species inside and outside a marine protected area.

By prohibiting fishing, marine protected areas (MPAs) provide a refuge for harvested species. Humans are often perceived as predators by prey and therefore respond fearfully to humans. Thus, fish responses to humans inside and outside of an MPA can provide insights into their perception of humans as a predatory threat. Previous studies have found differences in the distance that harvested species of fish initiate flight (flight initiation distance-FID) from humans inside and outside an MPA, but less is known about unharvested species. We focused on whether the lined bristletooth Ctenochaetus striatus, an unharvested surgeonfish, can discriminate between a snorkeler and a snorkeler with a spear gun inside and outside of a no-take MPA in Mo'orea, French Polynesia. Additionally, we incorporated starting distance (the distance between the person and prey at the start of an experimental approach), a variable that has been found to be important in assessing prey escape decisions in terrestrial species, but that has not been extensively studied in aquatic systems. Lined bristletooth FID was significantly greater in the presence of a spear gun and varied depending on if the spear gun encounter was inside or outside of the MPA. These results imply a degree of sophistication of fish antipredator behavior, generate questions as to how a nontargeted species of fish could acquire fear of humans, and demonstrate that behavioral surveys can provide insights about antipredator behavior

Structure of the saxiphilin:saxitoxin (STX) complex reveals a convergent molecular recognition strategy for paralytic toxins.

Dinoflagelates and cyanobacteria produce saxitoxin (STX), a lethal bis-guanidinium neurotoxin causing paralytic shellfish poisoning. A number of metazoans have soluble STX-binding proteins that may prevent STX intoxication. However, their STX molecular recognition mechanisms remain unknown. Here, we present structures of saxiphilin (Sxph), a bullfrog high-affinity STX-binding protein, alone and bound to STX. The structures reveal a novel high-affinity STX-binding site built from a "proto-pocket" on a transferrin scaffold that also bears thyroglobulin domain protease inhibitor repeats. Comparison of Sxph and voltage-gated sodium channel STX-binding sites reveals a convergent toxin recognition strategy comprising a largely rigid binding site where acidic side chains and a cation-π interaction engage STX. These studies reveal molecular rules for STX recognition, outline how a toxin-binding site can be built on a naïve scaffold, and open a path to developing protein sensors for environmental STX monitoring and new biologics for STX intoxication mitigation