AOIPS 3 user's guide. Volume 2: Program descriptions

The Atmospheric and Oceanographic Information Processing System (AOIPS) 3 is the version of the AOIPS software as of April 1989. The AOIPS software was developed jointly by the Goddard Space Flight Center and General Sciences Corporation. A detailed description of very AOIPS program is presented. It is intended to serve as a reference for such items as program functionality, program operational instructions, and input/output variable descriptions. Program descriptions are derived from the on-line help information. Each program description is divided into two sections. The functional description section describes the purpose of the program and contains any pertinent operational information. The program description sections lists the program variables as they appear on-line, and describes them in detail

Dampening prey cycle overrides the impact of climate change on predator population dynamics : a long-term demographic study on tawny owls

Funded by ERA-Net BiodivERsA NERC. Grant Numbers: NE/E010660/1, NE/F021402/1, NE/G002045/1Peer reviewedPublisher PD

Keck IR Spectroscopy of WZ Sge: Detection of Molecular Emission from the Accretion Disk

Time-resolved IR spectroscopy of WZ Sge was obtained using NIRSPEC on Keck II. We detect CO and H$_{\rm 2}$ emission from the accretion disk placing WZ Sge into a rarefied class of astronomical objects including YSOs and high luminosity early-type stars. During the eclipse phase, the molecular emission greatly weakens but no firm evidence for the secondary star is seen allowing new limits on its luminosity to be determined. The detection of molecular emission provides physical properties within the outer disk of T=3000K and N$_H$$>10^{10}$ cm$^{-3}$. Such a cool, dense region, not associated with areas of H I and He I emission, provides the first observational confirmation of predictions made by accretion disk models.Comment: 10 pages, 3 figures. Accepted for publication in ApJ Letter

Reuse of ideas and concepts for creative stimuli in engineering design

Creative idea generation is essential to novel concept development and ultimately innovation. The following paper describes an extensive industry-based study investigating the use of creative stimuli during a brainstorming session at the conceptual stages of design.A new approach to retrieving creative stimuli referred to as ‘Sweeper’ is proposed, which sources stimuli internal to a company’s information repository. This creative stimuli tool is then compared to other creative stimuli tools using objective, industrially grounded performance criteria. This study provides an arguably much needed real, industrially-based experiment regarding brainstorming. The results and observations suggest that having a guided approach to sourcing creative stimuli is very beneficial. The use of the TRIZ contradiction matrix and inventive principles is also shown to be a good example of a guided approach in terms of increasing creative performance. However, the Sweeper tool using internally sourced stimuli provides a method that is useful and more a practical alternative, as it is based firmly in the domain of activity

Computer-assisted polyp matching between optical colonoscopy and CT colonography: a phantom study

Potentially precancerous polyps detected with CT colonography (CTC) need to be removed subsequently, using an optical colonoscope (OC). Due to large colonic deformations induced by the colonoscope, even very experienced colonoscopists find it difficult to pinpoint the exact location of the colonoscope tip in relation to polyps reported on CTC. This can cause unduly prolonged OC examinations that are stressful for the patient, colonoscopist and supporting staff. We developed a method, based on monocular 3D reconstruction from OC images, that automatically matches polyps observed in OC with polyps reported on prior CTC. A matching cost is computed, using rigid point-based registration between surface point clouds extracted from both modalities. A 3D printed and painted phantom of a 25 cm long transverse colon segment was used to validate the method on two medium sized polyps. Results indicate that the matching cost is smaller at the correct corresponding polyp between OC and CTC: the value is 3.9 times higher at the incorrect polyp, comparing the correct match between polyps to the incorrect match. Furthermore, we evaluate the matching of the reconstructed polyp from OC with other colonic endoluminal surface structures such as haustral folds and show that there is a minimum at the correct polyp from CTC. Automated matching between polyps observed at OC and prior CTC would facilitate the biopsy or removal of true-positive pathology or exclusion of false-positive CTC findings, and would reduce colonoscopy false-negative (missed) polyps. Ultimately, such a method might reduce healthcare costs, patient inconvenience and discomfort.Comment: This paper was presented at the SPIE Medical Imaging 2014 conferenc

The combined absence of NF-kappa B1 and c-Rel reveals that overlapping roles for these transcription factors in the B cell lineage are restricted to the activation and function of mature cells

Transcription factors NF-KB1 and c-Rel, individually dispensable during embryogenesis, serve similar, yet distinct, roles in the function of mature hemopoietic cells. Redundancy among Rel/ NF-KB family members prompted an examination of the combined roles of c-Rel and NF-KB1 by using mice that lack both proteins. Embryonic development and the maturation of hemopoietic progenitors were unaffected in nfkb1(-/-)c-rel(-/-) mice. Peripheral T cell populations developed normally, but follicular, marginal zone, and CD5(+) peritoneal B cell populations all were reduced. In culture, a failure of mitogen-stimulated nfkb1(-/-)c-rel(-/-) B cells to proliferate was caused by a cell cycle defect in early G(1) that prevented growth. In vivo, defects in humoral immunity and splenic architecture seen in nfkbl(-/-) and c-rel(-/-) mice were exacerbated in the double mutant mice. These findings demonstrate that in the B lineage overlapping roles for NF-K81 and c-Rel appear to be restricted to regulating the activation and function of mature cells