4,686 research outputs found
Interfacing the Network: An Embedded Approach to Network Instrument Creation
This paper discusses the design, construction, and
development of a multi-site collaborative instrument,
The Loop, developed by the JacksOn4 collective during
2009-10 and formally presented in Oslo at the
arts.on.wires and NIME conferences in 2011. The
development of this instrument is primarily a reaction
to historical network performance that either attempts
to present traditional acoustic practice in a distributed
format or utilises the network as a conduit to shuttle
acoustic and performance data amongst participant
nodes. In both scenarios the network is an integral and
indispensible part of the performance, however, the
network is not perceived as an instrument, per se. The
Loop is an attempt to create a single, distributed hybrid
instrument retaining traditionally acoustic interfaces
and resonant bodies that are mediated by the network.
The embedding of the network into the body of the
instrument raises many practical and theoretical
discussions, which are explored in this paper through a
reflection upon the notion of the distributed instrument
and the way in which its design impacts the behaviour
of the participants (performers and audiences); the
mediation of musical expression across networks; the
bi-directional relationship between instrument and
design; as well as how the instrument assists in the
realisation of the creators’ compositional and artistic
goals
Atomic position localization via dual measurement
We study localization of atomic position when a three-level atom interacts
with a quantized standing-wave field in the Ramsey interferometer setup. Both
the field quadrature amplitude and the atomic internal state are measured to
obtain the atomic position information. It is found that this dual measurement
scheme produces an interference pattern superimposed on a diffraction-like
pattern in the atomic position distribution, where the former pattern
originates from the state-selective measurement and the latter from the field
measurement. The present scheme results in a better resolution in the position
localization than the field-alone measurement schemes. We also discuss the
measurement-correlated mechanical action of the standing-wave field on the atom
in the light of Popper's test.Comment: 6.5 pages and 5 figure
Geochemical-geophysical investigations, Fairbanks district
Trace element distribution in a subarctic valley in the Cleary Hill area of the Fairbanks gold district has been studied.
Zinc and arsenic have been found excellent pathfinder elements for auriferous deposits. Methods of analysis for copper, lead, zinc, molybdenum, silver and arsenic as well as heavy metals are discussed. The University of Alaska method #2 has been improved, Terrain, slope, and frozen ground have little effect upon the distribution of trace elements associated with the Cleary H i l l vein. A new method for the determination of zinc using dilute acid is proposed. Analysis of geochemical data by trend surface procedures proved effective for localization of anomalies
Scaling Flows and Dissipation in the Dilute Fermi Gas at Unitarity
We describe recent attempts to extract the shear viscosity of the dilute
Fermi gas at unitarity from experiments involving scaling flows. A scaling flow
is a solution of the hydrodynamic equations that preserves the shape of the
density distribution. The scaling flows that have been explored in the
laboratory are the transverse expansion from a deformed trap ("elliptic flow"),
the expansion from a rotating trap, and collective oscillations. We discuss
advantages and disadvantages of the different experiments, and point to
improvements of the theoretical analysis that are needed in order to achieve
definitive results. A conservative bound based on the current data is that the
minimum of the shear viscosity to entropy density ration is that eta/s is less
or equal to 0.5 hbar/k_B.Comment: 32 pages, prepared for "BCS-BEC crossoverand the Unitary Fermi Gas",
Lecture Notes in Physics, W. Zwerger (editor), Fig. 5 corrected, note added;
final version, corrected typo in equ. 9
The NF-ÎşB subunit c-Rel regulates Bach2 tumour suppressor expression in B-cell lymphoma
The REL gene, encoding the NF-κB subunit c-Rel, is frequently amplified in B-cell lymphoma and functions as a tumour-promoting transcription factor. Here we report the surprising result that c-rel–/– mice display significantly earlier lymphomagenesis in the c-Myc driven, Eμ-Myc model of B-cell lymphoma. c-Rel loss also led to earlier onset of disease in a separate TCL1-Tg-driven lymphoma model. Tumour reimplantation experiments indicated that this is an effect intrinsic to the Eμ-Myc lymphoma cells but, counterintuitively, c-rel–/– Eμ-Myc lymphoma cells were more sensitive to apoptotic stimuli. To learn more about why loss of c-Rel led to earlier onset of disease, microarray gene expression analysis was performed on B cells from 4-week-old, wild-type and c-rel–/– Eμ-Myc mice. Extensive changes in gene expression were not seen at this age, but among those transcripts significantly downregulated by the loss of c-Rel was the B-cell tumour suppressor BTB and CNC homology 2 (Bach2). Quantitative PCR and western blot analysis confirmed loss of Bach2 in c-Rel mutant Eμ-Myc tumours at both 4 weeks and the terminal stages of disease. Moreover, Bach2 expression was also downregulated in c-rel–/– TCL1-Tg mice and RelA Thr505Ala mutant Eμ-Myc mice. Analysis of wild-type Eμ-Myc mice demonstrated that the population expressing low levels of Bach2 exhibited the earlier onset of lymphoma seen in c-rel–/– mice. Confirming the relevance of these findings to human disease, analysis of chromatin immunoprecipitation sequencing data revealed that Bach2 is a c-Rel and NF-κB target gene in transformed human B cells, whereas treatment of Burkitt's lymphoma cells with inhibitors of the NF-κB/IκB kinase pathway or deletion of c-Rel or RelA resulted in loss of Bach2 expression. These data reveal a surprising tumour suppressor role for c-Rel in lymphoma development explained by regulation of Bach2 expression, underlining the context-dependent complexity of NF-κB signalling in cancer
Palynology of the interval 1796.78 to 2066.83 m of well 202/03a-3, Faroe-Shetland Basin
As part of Phase 3 of the BGS Faroe-Shetland Consortium project on the Jurassic of the UK sector of the Faroe-Shetland Basin, detailed logging of core from well 202/03a-3 was undertaken and samples were taken for palynology in order to provide additional facies information and age determinations.
The palynological assemblages were dominated by terrestrially derived pollen and spores. Marine palynomorph assemblages, were mostly made up of actitarchs and foraminiferal test linings, dinoflagellate cysts (dinocysts) being rare. A marine setting is indicated.
Rare specimens of the dinoflagellate cyst Liasidium variabile indicate the Late Sinemurian (Early Jurassic) in the lower core run. These palynological age determinations are compatible with ammonite specimens indicating the late Sinemurian Raricostatum ammonite zone (Raricostatoides subzone). In the other samples, negative evidence, such as the absence of heavily ornamented spores such as Cicatricosisporites, of the pollen genus Callialasporites, and of characteristic Triassic forms, suggests the Early Jurassic
Palynology of the interval 1358.12 to1446.0 m of well 202/12-1, Faroe-Shetland Basin
As part of Phase 3 of the BGS Faroe-Shetland Consortium project on the Jurassic of the UK sector of the Faroe-Shetland Basin, detailed logging of core from well 202/12-1 was undertaken and samples were taken for palynology in order to provide additional facies information and age determinations.
Samples 1 to 3 (1358.12 to 1361.41 m) yield age diagnostic palynomorphs indicating Early to Late Volgian ages. Sample 2 at 1359.8 m contains Dingodinium tuberosum and Gochteodinia villosa which bracket the age of the sample around the late Mid Volgian and the early Late Volgian (Oppressus–Primitivus zones) (Riding and Thomas, 1992). Marine influence is indicated periodically through the interval studied although the very sparse samples cannot be given a robust classification
Palynology of the interval 3169.84 to 3173.41 m of well 206/05-2, Faroe-Shetland Basin
As part of Phase 3 of the BGS Faroe-Shetland Consortium project on the Jurassic of the UK sector of the Faroe-Shetland Basin, detailed logging of core from well 206/05-2 was undertaken and samples were taken for palynology in order to provide additional facies information and age determinations. Analysis of kerogen and palynological assemblages revealed a generally poor run of samples lacking good age-diagnostic palynomorphs. A Volgian or younger age is tentatively assigned in Sample 5 at 3172.49 m by the presence of the spore genus Cicatricosisporites
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