Cone Monotonicity: Structure Theorem, Properties, and Comparisons to Other Notions of Monotonicity

In search of a meaningful 2-dimensional analog to mono- tonicity, we introduce two new definitions and give examples of and dis- cuss the relationship between these definitions and others that we found in the literature. Note: After we published the article in Abstract and Applied Analysis and after we searched multiple times for previous work, we discovered that Clarke at al. had introduced the definition of cone monotonicity and given a characterization. See the addendum at the end of this paper for full reference information

Dilaton constraints and LHC prospects

The Standard Model Higgs searches using the first 1-2 fb-1 of LHC data can be used to put interesting constraints on new scalar particles other than the Higgs. We investigate one such scenario in which electroweak symmetry is broken via strongly coupled conformal dynamics. This scenario contains a neutral scalar dilaton---the Goldstone boson associated with spontaneously broken scale invariance---with a mass below the conformal symmetry breaking scale and couplings to Standard Model particles similar (but not identical) to those of the Standard Model Higgs boson. We translate the LEP and LHC Higgs limits to constrain the dilaton mass and conformal breaking scale. The conformal breaking scale f is constrained to be above 1 TeV for dilaton masses between 145 and 600 GeV, though it can be as low as 400 GeV for dilaton masses below 110 GeV. We also show that (i) a dilaton chi with mass below 110 GeV and consistent with the LEP constraints can appear in gg --> chi --> gamma gamma with a rate up to ~10 times the corresponding Standard Model Higgs rate, and (ii) a dilaton with mass of several hundred GeV is much narrower than the corresponding Standard Model Higgs, leading to improved search sensitivity in chi --> ZZ --> 4l.Comment: 15 pages, 12 figures, References added, Figure 10 modified, Figure 11 adde

Doxycycline alters metabolism and proliferation of human cell lines.

The tetracycline antibiotics are widely used in biomedical research as mediators of inducible gene expression systems. Despite many known effects of tetracyclines on mammalian cells-including inhibition of the mitochondrial ribosome-there have been few reports on potential off-target effects at concentrations commonly used in inducible systems. Here, we report that in human cell lines, commonly used concentrations of doxycycline change gene expression patterns and concomitantly shift metabolism towards a more glycolytic phenotype, evidenced by increased lactate secretion and reduced oxygen consumption. We also show that these concentrations are sufficient to slow proliferation. These findings suggest that researchers using doxycycline in inducible expression systems should design appropriate controls to account for potential confounding effects of the drug on cellular metabolism

Private Landowners’ Willingness to Enroll Their Properties in a Public Hunting Access Program in Northeast Missouri

State wildlife agencies have successfully used public hunting access fees to increase hunting opportunity and to provide a financial incentive to private landowners for maintaining habitat. Typical payments per hectare (ac) include $3.29 ($1.25) on average in Kansas, $2.47-$3.71($1-$1.50) for pheasant hunting in Colorado, $2.47-$12.36 ($1–$5) in North Dakota for pheasant hunting, and $4.45 ($1.80) on average in South Dakota. We studied the USDA Conservation Reserve Program (CRP) in 2004 in Adair, Knox, Macon, Monroe, Ralls, Randolph, Schuyler, and Scotland counties in northeast Missouri as part of a quail and songbird habitat restoration initiative. CRP is prominent in these counties with 83,040 ha (205,197 ac) enrolled. We conducted a mail-back survey of all CRP contract holders, totaling 3,283 landowners to study their willingness to enroll their properties in a hypothetical public- access hunting program. The survey was designed to provide information about landowner demographics, attitudes toward wildlife and hunting, and knowledge of wildlife habitat management aspects of the CRP. We used the Kansas Department of Wildlife and Parks Walk-In Hunting Access Program as an example for questions related to the concept of public-access hunting, and presented landowners with hypothetical annual lease payments for enrolling, using a discrete-choice modeling framework. Survey response rate was relatively high at 59.5%. The average respondent had 34.6 ha (85.5 ac) enrolled in CRP, and field size averaged 6.47 ha (16.0 ac), ranging from 0.04 to 84.9 ha (0.1–209.7 ac). Wildlife as a product of the CRP was ‘very’ or ‘somewhat important’ to 89% of respondents and, among a list of wildlife species and native plants, northern bobwhite (Colinus virginianus) was most popular with 80% of respondents checking ‘very’ or ‘somewhat important’ on the survey. The corresponding values were 53–66% for wild turkey (Meleagris gallopavo), deer, rabbit, pheasant, and songbirds. We asked if landowners would enroll any of their CRP land in a public-access hunting program (PAHP). We used 8 different versions of the survey, each with a different ‘offer’ level in the question to evaluate the potential costs of a PAHP program. The structure of the survey specified whether landowners would accept payment of $X/ac, where X was one value randomly selected from the set of$1, $2,$3, $4,$5, $7,$10, or $20. None of respondents chose ‘yes’ at a PAHP value of$0, 91.9% chose ‘no’, and 8.1% chose ‘don’t know’; respective values ($) and choices ($1-1.7%, 91.3%, and 6.9%; $2-3.0$3-4.0%, 84.9%, and 11.2%; $4-3.4$5- 4.7%, 83.4%, and 11.9%; $7-7.1$10-8.4%, 77.0%, and 14.7%; and $20-14.8$2/ac ($4.94/ha), ~ 3$10,500. About 1,012 ha (2,500 ac) would be designated for quail hunting of this hypothetical PAHP area, based on respondents’ answers to what type of hunting they would allow. We estimate that 5,261 ha (13,000 ac) would be enrolled with 2,489 ha (6,150 ac) open for quail hunting at an annual cost of about $90,000 if the payment level was raised to$7/ac ($17.30/ha). There is potential to improve the feasibility of CRP lands for bobwhite hunting in northeast Missouri by adding a public-access hunting incentive, but managers will be challenged to use this approach successfully. Landowners’ inclination to allow access for deer hunting, but not for quail hunting, reduces an agency’s justification for using quail hunting access as an approach to improve conservation of bobwhites, in addition to the relatively high cost

Development of a Value-Added Database of Evaluated Systematic Reviews in Veterinary Medicine: DVM Evidence

Objectives: This presentation will describe the development of the Database of Veterinary Medicine Evidence (DVM Evidence). The database was created by collecting, annotating, and evaluating systematic reviews and meta-analyses of relevance to veterinary medicine. Methods: The process includes four steps, similar to conducting a systematic review: identification, selection, appraisal, and data abstraction. Identification includes searching bibliographic databases (MEDLINE, Cab Abstracts, and more), grey literature, and expert selected list of conference proceedings and journal titles. The selection and appraisal process was completed independently by 2 team members, with disagreements settled by consensus. The appraisal process utilized AMSTAR and PRISMA. The data abstraction form includes citation, review question, inclusion criteria, topic, resources searched, and list of included primary studies. The database will be open access and browsable by species, specialty area, and type of study as well as searchable by keywords, author(s), journal titles, and year. Collaboration will be sought with librarians, researchers, and veterinarians to add in various perspectives. Results: A pilot group of 20 studies was selected by the team’s systematic review expert based on criteria designed to facilitate training team members in appraisal, coding, and testing the coding form. The coding form which incorporates AMSTAR, PRISMA, and custom questions, was developed in Qualtrics, a subscription based survey tool. Although initially the survey format of Qualtrics had some promise as a tool for the coding form, several issues were found during the pilot phase. The team decided to build a custom form that provides more flexibility with importing and exporting data to and from the database, and more control in the desired outcome of the resource. The team chose MySQL for the database management system, and PHP as the scripting language, because these software are supported by the library IT department, powerful and flexible enough to accomplish the tasks, and common enough for others to adapt them as the database evolves and personnel change occurs. Graduate students, selected for their expertise with MySQL and PHP, created the database and public interfaces with design input from team members. During each step of the process, the team considered needs of potential external evaluators. Conclusions: Developing a systematic review database of this complexity takes a team with a variety of skills, strategic planning, and frequent checkpoints along the way. The next step will focus on the usability of the custom made form and the search interface with external evaluators

The Focus Group as a Demonstration Technique

Focus group interviews are research techniques, and demonstration projects are Extension techniques. Our title is a little misleading; we are merely proposing that many aspects of focus groups can be used to strengthen demonstrations. We describe a focus group field forestry interview that was described by participants as an outstanding demonstration. This was surprising because our project had no demonstration objective. We discuss four aspects of focus group methodology that might be incorporated into demonstrations in order to enhance educational effectiveness: group dynamics, reversed information flow, enhanced networking opportunity, and increased variables in demonstrations to facilitate more discussion

A map of the day-night contrast of the extrasolar planet HD 189733b

"Hot Jupiter" extrasolar planets are expected to be tidally locked because they are close (<0.05 astronomical units, where 1 AU is the average Sun-Earth distance) to their parent stars, resulting in permanent daysides and nightsides. By observing systems where the planet and star periodically eclipse each other, several groups have been able to estimate the temperatures of the daysides of these planets. A key question is whether the atmosphere is able to transport the energy incident upon the dayside to the nightside, which will determine the temperature at different points on the planet's surface. Here we report observations of HD 189733, the closest of these eclipsing planetary systems, over half an orbital period, from which we can construct a 'map' of the distribution of temperatures. We detected the increase in brightness as the dayside of the planet rotated into view. We estimate a minimum brightness temperature of 973 +/- 33 K and a maximum brightness temperature of 1212 +/- 11 K at a wavelength of 8 microns, indicating that energy from the irradiated dayside is efficiently redistributed throughout the atmosphere, in contrast to a recent claim for another hot Jupiter. Our data indicate that the peak hemisphere-integrated brightness occurs 16$\pm$6 degrees before opposition, corresponding to a hot spot shifted east of the substellar point. The secondary eclipse (when the planet moves behind the star) occurs 120 +/- 24 s later than predicted, which may indicate a slightly eccentric orbit.Comment: To appear in the May 10 2007 issue of Nature, 10 pages, 2 black and white figures, 1 colo