4,624 research outputs found

    In-between Images: Where is the Ground?

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    Joan Jonas’s large survey exhibition at Tate Modern (2018) highlighted the contemporary relevance of this pioneer of performance art in her juxtapositions of analogue and virtual methods. Her process often relies on a ground or stage where physical remnants of her performances are tangible. Drawing from these insights and exploring figure-ground relations through a selection of works by various artists and filmmakers, this article aims to challenge Hito Steyerl’s polemic that we might not need a ground within contemporary virtual image worlds. The consideration of case studies will be informed by philosophical reflections as to the relevance and scope of the idea of ground within the post-digital era

    Collisional Energy Loss of Fast Charged Particles in Relativistic Plasmas

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    Following an argument by Kirzhnits we rederive an exact expression for the energy loss of a fast charged particle in a relativistic plasma using the quantum field theoretical language. We compare this result to perturbative calculations of the collisional energy loss of an energetic electron or muon in an electron-positron plasma and of an energetic parton in the quark-gluon plasma.Comment: 9 pages, LATEX, 2 PostScript figure

    Using Active Learning Methods, Adult Learning Principles and the Identification of Critical to Quality (CTQ) Factors to Create Effective Site Staff Training Plans and Improve Quality Risk Management

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    Objective: The objective of this poster presentation is to help sponsors, monitors and clinical research site managers design and conduct more meaningful and effective site staff training activities in order to enhance the implementation of study protocols in accordance with the investigational plan and thus improve quality risk management. Content: The U.S. Food and Drug Administration (FDA), the International Council on Harmonization (ICH) and the European Medicines Agency (EMA) emphasize that sponsors should choose investigators, clinical research site staff and monitors that are qualified by education, training and experience. In addition, these entities have taken a more risk-based approach to managing and monitoring risks in recent years. This approach consists of focusing oversight on the risks related to human subjects protection, data integrity and investigation quality. All processes used to prevent and mitigate risks should be in direct proportion to the seriousness and likelihood of these risks. The ICH E6 (R2) noted that effective training in processes and procedures is one of the risk reduction activities that sponsors should employ. FDA’s 2013 guidance on risk-based monitoring noted that investigators and clinical research site staff need “meaningful training” prior to and during the conduct of a study in order to execute it correctly. In FY 2017, the most frequent finding on FDA Form 483 that was issued from inspections by FDA’s Bioresearch Monitoring Program was failure to conduct the investigation in accordance with the investigational plan. A common citation noted in warning letters to sponsors and investigators was the failure to have effective training and retraining activities. The challenge, therefore, is to design and conduct training activities that are meaningful and effective in order to correctly execute study protocols and reduce risks to human subjects protection, data integrity and investigation quality. Educational research has shown that active learning methods are much more effective at enhancing knowledge transfer and retention than passive learning methods such as reading, listening or watching a webcast. In this poster presentation, I will discuss various active learning methods that can be used to design and conduct meaningful and effective site training activities. I will discuss how these methods can be combined with adult learning principles and risk identification/assessment tools to design a site staff training plan that will identify the Critical to Quality (CTQ) factors, enhance the prevention and mitigation of risks that matter, and help staff to execute the study protocol in accordance with the investigational plan

    Medication Adherence and its Implications for Clinical Research: An Example from Low Income, Urban Young Adults Living with HIV/AIDS

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    Consistent medication adherence by study participants is essential for producing valid and reliable safety and efficacy data in clinical trials. Adherence to investigational medications can be a challenge, particularly for study participants who have complex medication regimens, a stigmatized illness such as HIV/AIDS or a mental health disorder, and risk factors for poor adherence such as young or old age, poor health status, cognitive issues, low health literacy, and low socioeconomic status. A deep understanding of the study population’s beliefs, attitudes, motivations, and prior experiences regarding medication adherence can assist clinical research professionals with predicting medication adherence potential during the recruitment phase along with supporting medication adherence during the study conduct phase. I will present excerpts from in-depth interviews with 16 low income, urban young adults living with HIV/AIDS about their beliefs, attitudes, motivations, and prior experiences about medication adherence. I will discuss how this information can be used by clinical research professionals who conduct clinical trials with this population to predict and support medication adherence. I will also discuss how collecting deep, rich qualitative data about the study population can assist the clinical research team with predicting and supporting medication adherence of study participants. This presentation will be of interest to clinical research professionals who conduct clinical trials with low income, urban young adults living with HIV/AIDS as well as for those interested in predicting and supporting medication adherence among study participants in general

    Damping Rate of a Yukawa Fermion at Finite Temperature

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    The damping of a massless fermion coupled to a massless scalar particle at finite temperature is considered using the Braaten-Pisarski resummation technique. First the hard thermal loop diagrams of this theory are extracted and effective Green's functions are constructed. Using these effective Green's functions the damping rate of a soft Yukawa fermion is calculated. This rate provides the most simple example for the damping of a soft particle. To leading order it is proportional to g2Tg^2T, whereas the one of a hard fermion is of higher order.Comment: 5 pages, REVTEX, postscript figures appended, UGI-94-0

    Beyond the Confines of Tolerance in Rachid Buchareb’s London River: Theological Discussion and Educational Approach to an Open Ended film

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    The article discusses Rachid Buchareb\u27s film London River both from a theological and an educational point of view. Therefore I argue that this film may be of great use in the lesson of Religious Education (or other subjects that concern multicultural and inter-religious affairs), for it raises some crucial existential issues, mainly: how do people of different ethnic, religious and cultural backgrounds truly connect to one another especially in cases in which these exact differences may be the cause of extreme suffering. This is actually the thematic concept of the film. Based on the teachings of the Bible and particularly, the Incarnation and the way it is elaborated throughout Christian tradition, I conclude that mere tolerance will not suffice if humans are to truly connect and embrace each other in spite of any racial, cultural and religious differences. The film presents us both with the obstacles on the road to a true encounter between different people (the two protagonists, who represent the Christian and Muslim identities) and the right steps towards an intimate relationship. It is a realistic depiction of inter-personal and inter-cultural relationships, which may be better approached in a classroom environment through the use of open-ended questions. The latter promote analytical and creative thinking, which is necessary when we examine complex existential issues. This is the focal point of my educational approach to the film and in order to support it, I suggest a set of open-ended questions that may address the problems and issues that the film portrays. Within the same context, I also argue that doubt, which seems to pervade the whole story, can turn from a life and faith-consuming experience to a reason for a meaningful bond between people who come to experience it. The open-ended story of London River may denote a possibility of a better future regarding multi-ethic-religious affairs, based on the mutual desire for a genuine connection, friendliness and openness towards otherness that the Christian faith proposes. In this regard, Christian Churches should make use of the pattern of Incarnation outside the confines of mere adoption of a Christian doctrine. In terms of their dialogue with members of other religious traditions, they could see Incarnation as a starting point for the establishment of a common ground for the sake of peace and reconciliation

    Study of ambiguities in πpΛK0\pi^-p\to \Lambda K^0 scattering amplitudes

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    Amplitudes for the reaction πpΛK0\pi^-p\to \Lambda K^0 are reconstructed from data on the differential cross section dσ/dΩd\sigma/d\Omega, the recoil polarization PP, and on the spin rotation parameter β\beta. At low energies, no data on β\beta exist, resulting in ambiguities. An approximation using SS and PP waves leads only to a fair description of the data on dσ/dΩd\sigma/d\Omega and PP; in this case, there are two sets of amplitudes. Including DD waves, the data on dσ/dΩd\sigma/d\Omega and PP are well reproduced by the fit but now, there are several distinct solutions which describe the data with identical precision. In the range where the spin rotation parameter β\beta was measured, a full and unambiguous reconstruction of the partial wave amplitudes is possible. The energy-independent amplitudes are compared to the energy dependent amplitudes which resulted from a coupled channel fit (BnGa2011-02) to a large data set including both pion and photo-induced reactions. Significant deviations are observed. Consistency between energy dependent and energy independent solutions by choosing the energy independent solution which is closest to the energy dependent solution. In a second step, the {\it known} energy dependent solution for low (or high) partial waves is imposed and only the high (or low) partial waves are fitted leading to smaller uncertainties
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