Comparison of glycated albumin levels before and after periodontal treatment in type 2 diabetes patients with periodontitis

Background: Periodontal disease is closely related to type 2 diabetes and is an important complication of diabetes. Aim: This study aimed to investigate the effect of periodontal treatment on levels of blood glucose (Glu) and glycated albumin (GA) among patients with type 2 diabetes and periodontal disease. Methods: A total of 150 patients with type 2 diabetes and periodontal disease were selected and divided into two groups according to their GA levels. Group A was a well-controlled diabetic group and group B was uncontrolled. Their probing depth (PD), attachment loss (AL), the value of glucose and GA were analyzed before periodontal treatment and every two weeks in two months interval after. Results: There was a significant difference in periodontal condition between groups A and B (P <0.01). The periodontal condition for both groups was significantly (P <0.01) improved after periodontal therapy. The effect of treatment in group A was more pronounced than group B, and the difference was significant (P <0.01). After the periodontal treatment, Glu and GA were reduced significantly in both groups (P <0.05). Conclusion: Periodontal condition is related to the control of glucose level among patients with type 2 diabetes and periodontal disease. Periodontal treatment can effectively reduce the level of glucose and GA as well as it improves the periodontal condition in type-2 diabetes patients with periodontal disease