6 research outputs found
Fourâchannel selfâcompensating singleâslope ADC for space environments
- Author
- Publication venue
- 'Institution of Engineering and Technology (IET)'
- Publication date
- Field of study
A VP3/VP1 gene polymerase chain reaction assay for detection of chicken anemia virus in broiler samples
- Author
- A.J.P. Ferreira
- BOOM R.
- BRENTANO L.
- DAWSON M.D.
- E.O. Nogueira
- FORBES B.A.
- GELDERBLOM H.
- GORYO M.
- GORYO M.
- HOFREITER M.
- HU L.
- INNIS M.A.
- KATO A.
- L. Brentano
- LUCIO B.A.
- NOGUEIRA E.O.
- NOTEBORN M.H.M.
- NOTEBORN M.H.M.
- NOTEBORN M.H.M.
- PHENIX K.V.
- PRINGLE C.R.
- RELMAN D.A.
- RENSHAW R.W.
- RITCHIE B.W.
- SOINĂ C.
- THAM K.M.
- TODD D.
- TODD D.
- VON BĂLOW V.
- YUASA N.
- YUASA N.
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Genetic insights into resting heart rate and its role in cardiovascular disease.
- Author
- Appel E.A.
- Arking D.V.
- Arnar D.O.
- Assimes T.
- Auro K.
- Balkau B.
- Bandinelli S.
- Berg M.E. van den
- Bielak L.F.
- Boehnke M.
- Bottinger E.P.
- Bouchard C.
- Brody J.
- Burgess S.
- Campbell A.
- Chambers J.C.
- Cheng C.Y.
- Cocca M.
- Concas M.P.
- Cornelis M.C.
- Correa A.
- Cusi D.
- DCCT EDIC Res Grp
- Degenhardt F.
- Delgado G.E.
- Doerr M.
- Duijn C.M. van
- Eijgelsheim M.
- Ende M.Y. van der
- Eppinga R.N.
- Erdmann J.
- Eriksson J.G.
- Faul J.D.
- Feitosa M.F.
- Felix S.B.
- Ferrucci L.
- Foco L.
- Franke A.
- Froguel P.
- Galesloot T.E.
- Geus E.J.C. de
- Girotto G.
- Graaf J. de
- Grarup N.
- Groop L.
- Gudbjartsson D.F.
- Gudnason V.
- Guo X.Q.
- Gyllensten U.
- Hagemeijer Y.
- Hansen T.
- Harst P. van der
- Hayward C.
- Heckbert S.R.
- Hicks A.A.
- Hoed M. den
- Holm H.
- Hwang S.J.
- Ingelsson M.
- Iribarren C.
- Isaacs A.
- Jackson A.U.
- Johansson A.
- Joshi P.K.
- Jukema J.W.
- Kaeaeb S.
- Kaehoenen M.
- Kardia S.L.R.
- Kiemeney L.A.L.M.
- Kleber M.E.
- Kolcic I.
- Kooner J.S.
- Kraft P.
- Ladenvall C.
- Lahti J.
- Lakatta E.L.M.
- Lange L.
- Launer L.
- Lecoeur C.
- Lehtimaeki T.
- Li H.M.
- Lieb W.
- Lin H.E.
- Lind L.
- Lindgren C.
- Linneberg A.
- Loos R.J.F.
- Lorentzon M.
- Luan J.A.
- Lyytikaeinen L.P.
- Macfarlane P.W.
- Maerz W.
- Mahendran Y.V.
- Meitinger T.
- Melander O.
- Milaneschi Y.
- Moebus S.
- Mohlke K.L.
- Mononen N.
- Mook-Kanamori D.O.
- Morris A.P.
- Morrison A.C.
- Most P.J. van der
- Mueller-Nurasyid M.
- Munroe P.B.
- Mutsert R. de
- Nethander M.
- Newton-Cheh C.H.
- Nikus K.
- Nolte I.M.
- Noordam R.
- Ntalla I.
- O'Donnell C.J.
- Ohlsson C.
- Oldehinkel A.J.
- Ormel J.
- Padmanabhan S.
- Palmer C.N.A.
- Paterson A.D.
- Pavani F.
- Pechlivanis S.
- Penninx B.W.J.H.
- Perola M.
- Peters A.
- Peyser P.A.
- Pistis G.
- Polasek O.
- Porteous D.J.
- Psaty B.M.
- Qi L.
- Quek D.Q.
- Raitakari O.T.
- Rankinen T.
- Rao D.C.
- Riese H.
- Ring S.S.M.
- Rizzi F.
- Robino A.
- Roselli C.
- Roshandel D.
- Rotter J.I.
- Rueedi R.
- Sabanayagam C.
- Said M.A.
- Salfati E.Y.
- Salo P.
- Schraut K.E.
- Schunkert H.
- Schurmann C.
- Sever P.
- Shah N.B.
- Silva C.T.
- Sim X.S.
- Sinagra G.
- Sinner M.F.
- Smith A.E.
- Smith J.A.
- Smith J.G.
- Snieder H.
- Sotoodehnia N.
- Stefansson K.
- Stolarz-Skrzypek K.
- Strachan D.P.
- Strauch K.
- Sundstroem J.
- Sveinbjornsson G.
- Tai E.S.
- Tan N.C.L.
- Tan V.
- Tanaka T.
- Tarasov K.V.
- Taylor K.D.
- Tham Y.C.
- Timpson N.J.
- Trompet S.
- Ulivi S.
- Vegte Y. van de
- Verweij N.
- Vollenweider P.
- Vries P.S. de
- Waldenberger M.
- Wang L.H.
- Wareham N.J.
- Weir D.R.
- Weiss S.
- Wilson J.F.
- Witte D.R.
- Wong T.Y.
- Yao J.
- Zeng L.Y.
- Zhang W.H.
- Zhao J.H.
- Zhao W.
- Publication venue
- Nature Research
- Publication date
- 01/01/2023
- Field of study
Resting heart rate is associated with cardiovascular diseases and mortality in observational and Mendelian randomization studies. The aims of this study are to extend the number of resting heart rate associated genetic variants and to obtain further insights in resting heart rate biology and its clinical consequences. A genome-wide meta-analysis of 100 studies in up to 835,465 individuals reveals 493 independent genetic variants in 352 loci, including 68 genetic variants outside previously identified resting heart rate associated loci. We prioritize 670 genes and in silico annotations point to their enrichment in cardiomyocytes and provide insights in their ECG signature. Two-sample Mendelian randomization analyses indicate that higher genetically predicted resting heart rate increases risk of dilated cardiomyopathy, but decreases risk of developing atrial fibrillation, ischemic stroke, and cardio-embolic stroke. We do not find evidence for a linear or non-linear genetic association between resting heart rate and all-cause mortality in contrast to our previous Mendelian randomization study. Systematic alteration of key differences between the current and previous Mendelian randomization study indicates that the most likely cause of the discrepancy between these studies arises from false positive findings in previous one-sample MR analyses caused by weak-instrument bias at lower P-value thresholds. The results extend our understanding of resting heart rate biology and give additional insights in its role in cardiovascular disease development
Antiviral activity of Lactobacillus reuteri Protectis against Coxsackievirus A and Enterovirus 71 infection in human skeletal muscle and colon cell lines
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 24/06/2016
- Field of study
10.1186/s12985-016-0567-6Virology Journal13111
Chicken anaemia virus infection: Molecular basis of pathogenicity
- Author
- Adair B.M.
- Adair B.M.
- Akiyama Y.
- Ameisen J.
- Arends M.J.
- Bolow V. Von
- Bolow V. Von
- Boyle D.B.
- Bursch W.
- BĂŒlow V. von
- Chandratilleke D.
- Chou Q.
- Claessens J.A.J.
- Clarke A.R.
- Cohen J.J.
- D'Arpa P.
- D'Halluin J.C.
- De Boer G.F.
- Debbas M.
- Duvall E.
- Engström B.E.
- Forloni G.
- Gelderblom H.
- Goldstein P.
- Goryo M.
- Goryo M.
- Guus Koch
- Hartley S.B.
- Henderson S.
- Hershberger P.A.
- Hinshaw V.S.
- Hollstein M.
- Hoop R.K.
- Hu L.B.
- Hu L.âB.
- Jeurissen S.H.M.
- Jeurissen S.H.M.
- Jeurissen S.H.M.
- Kato A.
- Kerr J.F.R.
- KluinâNelemans J.C.
- Koch G.
- Kornberg A.
- Kozak M.
- Kyprianou N.
- Leibowttz J.
- Lowe S.W.
- Lucio B.
- Martin S.J.
- Mathieu H. M. Noteborn
- McConnell C.D.G.
- McConnell C.D.G.
- McGahon A.
- McIlroy S.G.
- McNulty M.S.
- McNulty M.S.
- McNulty M.S.
- McNulty M.S.
- McNulty M.S.
- McNulty M.S.
- McNulty M.S.
- Meehan B.M.
- Meyaard L.
- Morein B.
- Morey A.L.
- Morgan R.W.
- Nazerian K.
- Noteborn M.H.M.
- Noteborn M.H.M.
- Noteborn M.H.M.
- Noteborn M.H.M.
- Noteborn M.H.M.
- Noteborn M.H.M.
- Otaki Y.
- Pallister J.
- Persson H.
- Phenk K.V.
- Raff M.C.
- Razvi E.S.
- Ritchie B.W.
- Rosenberger J.K.
- Savili J.
- Shi L.
- Soiné C.
- Studdert M.J.
- Taylor S.P.
- Tham K.M.
- Tischer I.
- Todd D.
- Todd D.
- Todd D.
- Todd D.
- Tsujimoto Y.
- Urlings H.A.P.
- Vasconcelos A.C.
- Vielitz E.
- Vielitz E.
- Vlak J.M.
- WatanabeâFukunaga R.
- Wyllie A.H.
- Wyllie A.H.
- YonishâRouach E.
- Yuasa N.
- Yuasa N.
- Zhuang SâM.
- Zhuang SâM.
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight
- Publication venue
- Publication date
- 01/01/2021
- Field of study
From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, and severe obesity in different regions using data from 2896 population-based studies with 187 million participants. Changes in the prevalence of underweight and total obesity, and to a lesser extent severe obesity, are largely driven by shifts in the distribution of BMI, with smaller contributions from changes in the shape of the distribution. In East and Southeast Asia and sub-Saharan Africa, the underweight tail of the BMI distribution was left behind as the distribution shifted. There is a need for policies that address all forms of malnutrition by making healthy foods accessible and affordable, while restricting unhealthy foods through fiscal and regulatory restrictions. © Copyright