Endotension is Influenced by Wall Compliance in a Latex Aneurysm Model

AbstractObjectives. Even though endovascular aneurysm repair (EVAR) creates a closed chamber except for patent branches, the intra-sac pressure is never zero. This study was designed to investigate whether, and to what extent, aneurysm wall compliance influences intra-sac pressure.Design. In vitro experimental study.Methods. Aneurysm models with six and 12 latex layers were produced, resulting in elastic and stiff circumferential compliance (3.5±0.5 and 0.9±0.3%/100 mmHg, respectively). The models with an 18 mm internal neck and maximum aneurysm diameter of 60 mm were inserted into an in vitro circulation system. The systemic mean pressure (SPmean) was varied from 50 to 120 mmHg. After the aneurysm was excluded with a knitted polyethylene graft, aneurysm sac mean pressure (ASPmean) and aneurysm sac pulse pressure (ASPpulse) were measured. Data are presented as mean±SD. Statistics were performed using repeated measurements of variance; p<0.05 was considered significant.Results. In the model EVAR created a closed chamber without endoleak, but with an aneurysm sac pressure related to wall compliance. In the elastic aneurysm model with six latex coats the aneurysm sac mean pressure (ASPmean) and the aneurysm sac pulse pressure (ASPpulse) at all systemic pressures were significantly lower than they were in the stiffer model with 12 latex coats (p<0.05). At a SPmean of 90 mmHg, the ASPmean was 21.0±0.9 mmHg (six latex coats) and 26.0±0.2 mmHg (12 latex coats) (p<0.05), the ASPpulse was 5.7±0.2 mmHg (six latex coats) and 8.8±0.3 mmHg (12 latex coats) (p<0.05).Conclusions. This in vitro model demonstrated that the aneurysm sac mean pressure (ASPmean) and the aneurysm sac pulse pressure (ASPpulse) were significantly influenced by the compliance of the aneurysm wall. These data highlight the need for further studies regarding endotension

A New Non-Perturbative Approach to Quantum Theory in Curved Spacetime Using the Wigner Function

A new non-perturbative approach to quantum theory in curved spacetime and to quantum gravity, based on a generalisation of the Wigner equation, is proposed. Our definition for a Wigner equation differs from what have otherwise been proposed, and does not imply any approximations. It is a completely exact equation, fully equivalent to the Heisenberg equations of motion. The approach makes different approximation schemes possible, e.g. it is possible to perform a systematic calculation of the quantum effects order by order. An iterative scheme for this is also proposed. The method is illustrated with some simple examples and applications. A calculation of the trace of the renormalised energy-momentum tensor is done, and the conformal anomaly is thereby related to non-conservation of a current in d=2 dimensions and a relationship between a vector and an axial-vector current in d=4 dimensions. The corresponding ``hydrodynamic equations'' governing the evolution of macroscopic quantities are derived by taking appropriate moments. The emphasis is put on the spin-1/2 case, but it is shown how to extend to arbitrary spins. Gravity is treated first in the Palatini formalism, which is not very tractable, and then more successfully in the Ashtekar formalism, where the constraints lead to infinite order differential equations for the Wigner functions.Comment: LaTeX2e (uses amssymb), 36 page

Energetic and spatial bonding properties from angular distributions of ultraviolet photoelectrons: application to the GaAs(110) surface

Angle-resolved ultraviolet photoemission spectra are interpreted by combining the energetics and spatial properties of the contributing states. One-step calculations are in excellent agreement with new azimuthal experimental data for GaAs(110). Strong variations caused by the dispersion of the surface bands permit an accurate mapping of the electronic structure. The delocalization of the valence states is discussed analogous to photoelectron diffraction. The spatial origin of the electrons is determined, and found to be strongly energy dependent, with uv excitation probing the bonding region.Comment: 5 pages, 3 figures, submitted for publicatio

Raman Scattering Study of Ba-doped C60 with t1g States

Raman spectra are reported for Ba doped fullerides, BaxC60(x=3,4,and 6). The lowest frequency Hg modes split into five components for Ba4C60 and Ba6C60 even at room temperature, allowing us a quantitative analysis based on the electron-phonon couping theory. For the superconducting Ba4C60, the density of states at the Fermi energy was derived as 7 eV-1, while the total value of electron-phonon coupling \lambda was found to be 1.0, which is comparable to that of K3C60. The tangential Ag(2) mode, which is known as a sensitive probe for the degree of charge transfer on C60 molecule, shows a remarkable shift depending on the Ba concentration, being roughly consistent with the full charge transfer from Ba to C60. An effect of hybridization between Ba and C60 \pi orbitals is also discussed.Comment: 15 pages, 6 figures submitted to Phys. Rev. B (December 1,1998

Resolving the B[e] star Hen 3-1191 at 10 microns with VLTI/MIDI

We report spatially resolved, spectrally dispersed N-band observations of the B[e] star Hen 3-1191 with the MIDI instrument of the Very Large Telescope Interferometer. The object is resolved with a 40 m baseline and has an equivalent uniform disc diameter ranging from 24 mas at 8 microns to 36 mas at 13 microns. The MIDI spectrum and visibilities show a curvature which can arise from a weak silicate feature in which the object appears ~ 15% larger than in the continuum, but this could result from a change in the object's geometry within the band. We then model Hen's 3-1191 spectral energy distribution (.4-60 microns) and N-band visibilities. Because of the unknown nature for the object, we use a wide variety of models for objects with IR excesses. We find the observations to be consistent with a disc featuring an unusually high mass accretion and a large central gap almost void of matter, an excretion disc, and a binary made of two IR sources. We are unable to find a circumstellar shell model consistent with the data. At last, we review the different hypotheses concerning the physical nature of the star and conclude that it is neither a Be supergiant nor a symbiotic star. However, we could not discriminate between the scenario of a young stellar object featuring an unusually strong FU Orionis-like outburst of mass accretion (4 to 250 x 10^-4 solar mass per year) and that of a protoplanetary nebula with an equatorial mass excretion rate (>~ 4 x 10^-5 solar mass per year). In both cases, taking the additional presence of an envelope or wind into account would result in lower mass flows.Comment: 9 pages, 8 figures, 4 tables, 1 SIMBAD object Accepted by Astronomy & Astrophysics (manuscript AA-2006-6026

Genome sequencing of the extinct Eurasian wild aurochs, Bos primigenius, illuminates the phylogeography and evolution of cattle

Background Domestication of the now-extinct wild aurochs, Bos primigenius, gave rise to the two major domestic extant cattle taxa, B. taurus and B. indicus. While previous genetic studies have shed some light on the evolutionary relationships between European aurochs and modern cattle, important questions remain unanswered, including the phylogenetic status of aurochs, whether gene flow from aurochs into early domestic populations occurred, and which genomic regions were subject to selection processes during and after domestication. Here, we address these questions using whole-genome sequencing data generated from an approximately 6,750-year-old British aurochs bone and genome sequence data from 81 additional cattle plus genome-wide single nucleotide polymorphism data from a diverse panel of 1,225 modern animals. Results Phylogenomic analyses place the aurochs as a distinct outgroup to the domestic B. taurus lineage, supporting the predominant Near Eastern origin of European cattle. Conversely, traditional British and Irish breeds share more genetic variants with this aurochs specimen than other European populations, supporting localized gene flow from aurochs into the ancestors of modern British and Irish cattle, perhaps through purposeful restocking by early herders in Britain. Finally, the functions of genes showing evidence for positive selection in B. taurus are enriched for neurobiology, growth, metabolism and immunobiology, suggesting that these biological processes have been important in the domestication of cattle. Conclusions This work provides important new information regarding the origins and functional evolution of modern cattle, revealing that the interface between early European domestic populations and wild aurochs was significantly more complex than previously thought

High intensity neutrino oscillation facilities in Europe

The EUROnu project has studied three possible options for future, high intensity neutrino oscillation facilities in Europe. The first is a Super Beam, in which the neutrinos come from the decay of pions created by bombarding targets with a 4 MW proton beam from the CERN High Power Superconducting Proton Linac. The far detector for this facility is the 500 kt MEMPHYS water Cherenkov, located in the Fréjus tunnel. The second facility is the Neutrino Factory, in which the neutrinos come from the decay of μ+ and μ− beams in a storage ring. The far detector in this case is a 100 kt magnetized iron neutrino detector at a baseline of 2000 km. The third option is a Beta Beam, in which the neutrinos come from the decay of beta emitting isotopes, in particular He6 and Ne18, also stored in a ring. The far detector is also the MEMPHYS detector in the Fréjus tunnel. EUROnu has undertaken conceptual designs of these facilities and studied the performance of the detectors. Based on this, it has determined the physics reach of each facility, in particular for the measurement of CP violation in the lepton sector, and estimated the cost of construction. These have demonstrated that the best facility to build is the Neutrino Factory. However, if a powerful proton driver is constructed for another purpose or if the MEMPHYS detector is built for astroparticle physics, the Super Beam also becomes very attractive