27 research outputs found

    Mountain Risks: two case histories of landslides induced by artificial rainfall on steep slopes

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    Mountainous areas tend to be exposed to an enhanced risk of damage caused by natural hazards; most often exacerbated by the topography (leading to gravitational mass movements such as avalanches, landslides, mud and debris flows). This contribution compares landslides induced by artificial rainfall on two different areas located in Switzerland. One field test site was located on slopes above Saas Balen (Gruben glacier, Canton Wallis, Switzerland) and was instrumented. Artificial rainfall tests were carried out in the summers of 1999 and 2000 to investigate hydro-mechanical mechanisms of instability (Teysseire et al., 2000). Shallow failure occurred in the steeper instrumented slope in 2000. The second test field is located near Ruedlingen (Canton Schaffhausen, Switzerland). A landslide triggering experiment was carried out there in autumn 2008 and spring 2009 to replicate the effects of a heavy rainfall event of May 2002, in which 100 mm rain fell in 40 minutes, causing 42 superficial landslides. The slope was subjected to extreme rainfall by artificial means in October 2008 and in March 2009, triggering about 130 m3 of debris. Infiltration of rainfall has led to surface instability slopes in an alpine moraine (Gruben) and in silty sand (Ruedlingen). Both slopes were steeper than the internal angle of friction, having different initial degrees of saturation and suction. The hydromechanical behaviour of these two field full scale landslides will be compared, trying to expose a deeper understanding of the rainfall induced failure mechanisms

    Viral epidemics in a cell culture: novel high resolution data and their interpretation by a percolation theory based model

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    Because of its relevance to everyday life, the spreading of viral infections has been of central interest in a variety of scientific communities involved in fighting, preventing and theoretically interpreting epidemic processes. Recent large scale observations have resulted in major discoveries concerning the overall features of the spreading process in systems with highly mobile susceptible units, but virtually no data are available about observations of infection spreading for a very large number of immobile units. Here we present the first detailed quantitative documentation of percolation-type viral epidemics in a highly reproducible in vitro system consisting of tens of thousands of virtually motionless cells. We use a confluent astroglial monolayer in a Petri dish and induce productive infection in a limited number of cells with a genetically modified herpesvirus strain. This approach allows extreme high resolution tracking of the spatio-temporal development of the epidemic. We show that a simple model is capable of reproducing the basic features of our observations, i.e., the observed behaviour is likely to be applicable to many different kinds of systems. Statistical physics inspired approaches to our data, such as fractal dimension of the infected clusters as well as their size distribution, seem to fit into a percolation theory based interpretation. We suggest that our observations may be used to model epidemics in more complex systems, which are difficult to study in isolation.Comment: To appear in PLoS ONE. Supporting material can be downloaded from http://amur.elte.hu/BDGVirus

    Lesson learnt from field tests in some potentially unstable slopes in switzerland

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    Rain-induced slope instability is a significant natural hazard in Switzerland, Slovenia and elsewhere in Europe. This contribution was prepared especially for the 12th Ć uklje Symposium, and recognises that landslides occur both in mountain regions as well as in lowland regions during and following extreme-rainfall conditions. The Institute (and Professorship) for Geotechnical Engineering at the Swiss Federal Institute of Technology (ETH Zurich) has been engaged over several years in projects concerned with the characterisation, monitoring and modelling behaviour of slopes in mainly granular porous media across the full range of altitudes in Switzerland. A link is made to the doyen of the Ć uklje day and then three case histories are presented and discussed to demonstrate the principal reactions to seasonal rainfall. A small slip was released in two of these cases and the "triggering" factors have been investigated and are discussed in this contribution. It transpires that the mode of inslope drainage influences the way in which the ground saturates and hence the volume of the potentially unstable ground. Simple stability analyses using limit equilibrium and soil parameters that have been amended to account for unsaturated soil behaviour were found to function well for slopes in largely granular medi

    Lesson learnt from field tests in some potentially unstable slopes in switzerland

    Get PDF
    Rain-induced slope instability is a significant natural hazard in Switzerland, Slovenia and elsewhere in Europe. This contribution was prepared especially for the 12th Ć uklje Symposium, and recognises that landslides occur both in mountain regions as well as in lowland regions during and following extreme-rainfall conditions. The Institute (and Professorship) for Geotechnical Engineering at the Swiss Federal Institute of Technology (ETH Zurich) has been engaged over several years in projects concerned with the characterisation, monitoring and modelling behaviour of slopes in mainly granular porous media across the full range of altitudes in Switzerland. A link is made to the doyen of the Ć uklje day and then three case histories are presented and discussed to demonstrate the principal reactions to seasonal rainfall. A small slip was released in two of these cases and the "triggering" factors have been investigated and are discussed in this contribution. It transpires that the mode of inslope drainage influences the way in which the ground saturates and hence the volume of the potentially unstable ground. Simple stability analyses using limit equilibrium and soil parameters that have been amended to account for unsaturated soil behaviour were found to function well for slopes in largely granular medi

    Mountain Risks: two case histories of landslides induced by artificial rainfall on steep slopes

    No full text
    Mountainous areas tend to be exposed to an enhanced risk of damage caused by natural hazards; most often exacerbated by the topography (leading to gravitational mass movements such as avalanches, landslides, mud and debris flows). This contribution compares landslides induced by artificial rainfall on two different areas located in Switzerland. One field test site was located on slopes above Saas Balen (Gruben glacier, Canton Wallis, Switzerland) and was instrumented. Artificial rainfall tests were carried out in the summers of 1999 and 2000 to investigate hydro-mechanical mechanisms of instability (Teysseire et al., 2000). Shallow failure occurred in the steeper instrumented slope in 2000. The second test field is located near Ruedlingen (Canton Schaffhausen, Switzerland). A landslide triggering experiment was carried out there in autumn 2008 and spring 2009 to replicate the effects of a heavy rainfall event of May 2002, in which 100 mm rain fell in 40 minutes, causing 42 superficial landslides. The slope was subjected to extreme rainfall by artificial means in October 2008 and in March 2009, triggering about 130 m3 of debris. Infiltration of rainfall has led to surface instability slopes in an alpine moraine (Gruben) and in silty sand (Ruedlingen). Both slopes were steeper than the internal angle of friction, having different initial degrees of saturation and suction. The hydromechanical behaviour of these two field full scale landslides will be compared, trying to expose a deeper understanding of the rainfall induced failure mechanisms

    Supplementary Material for: Dermoscopic Features of Subungual Squamous Cell Carcinoma: A Study of 44 Cases

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    <i>Background:</i> Subungual squamous cell carcinoma (SSCC) is the most frequent tumor of the nail apparatus. Its diagnosis is often missed or delayed because the clinical presentation is atypical and can mimic other conditions. Accurate diagnosis can only be made by performing an appropriate surgical biopsy, but biopsy is painful and often leaves definitive dystrophic scars. The use of dermoscopy, a noninvasive technique, has been described to be useful for the preoperative evaluation of nail diseases. <i>Objectives:</i> To define the different clinical and dermoscopic presentations of SSCC and to compare them with onychomatricoma-associated clinical and dermoscopic features published in our previous study. <i>Methods:</i> A retrospective review of 44 cases of SSCC seen in our institution over an 8-year period. Six observers scored 19 clinical criteria and 14 dermoscopic criteria as present or absent. Then, we compared those data to a previously published study about the preoperative diagnosis of onychomatricoma. <i>Results:</i> Only 1 dermoscopic criterion was significantly associated with SSCC compared to onychomatricoma: localized hyperkeratosis (odds ratio, OR = 6.25, <i>p</i> = 0.012, 95% confidence interval CI = 1.50-26.01). In contrast, parallel edges (OR = 0.03, <i>p</i> < 0,001, 95% CI = 0.003-0.20) and sharp demarcation of the lesion (OR = 0.24, <i>p</i> = 0.004, 95% CI = 0.09-0.63) can statistically significantly be considered as in favor of onychomatricoma. By contrast, we believe that the presence of unparalleled lateral edges of the nail lesion or of fuzzy edges are more in favor of SSCC. <i>Conclusions:</i> Dermoscopy of the nail plate and of the nail free edge in SSCC provides useful information in order to better select cases to be submitted to biopsy
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