579 research outputs found
Multiple abnormalities in the skull of a prostitute. An autopsy report (1900)
OBJECTIVE: The study presents and comments on the publication of an autopsy report. CASE REPORT: In 1900 De Blasio published an article entitled "Multiple abnormalities in a prostitute's skull" in the "Journal of Psychiatry, Criminal Anthropology and related sciences". In this work De Blasio related anomalies at the cranial level to the presence of mental pathologies. The skull belonged to a 24-year-old prostitute who died of syphilitic hepatitis. In his article, De Blasio described the life of the woman, after which he gave a macroscopic description of the skull. De Blasio believed that the subject's amoral behavior was caused by the anomalous shape of the subject's skull. CONCLUSION: From the study, it is evident that the school of criminal anthropology influenced De Blasio's autopsy medical practice, and it is interesting to note the interpretation of anthropologists of the time who tried to describe the link between physical and behavioral anomalies
The economic implications of HLA matching in cadaveric renal transplantation.
Abstract
Background: The potential economic effects of the allocation of cadaveric kidneys on the basis of tissue-matching criteria are controversial. We analyzed the economic costs associated with the transplantation of cadaveric kidneys with various numbers of HLA mismatches and examined the potential economic benefits of a local, as compared with a national, system designed to minimize HLA mismatches between donor and recipient in first cadaveric renal transplantations. Methods: All data were supplied by the U.S. Renal Data System. Data on all payments made by Medicare from 1991 through 1997 for the care of recipients of a first cadaveric renal transplant were analyzed according to the number of HLA-A, B, and DR mismatches between donor and recipient and the duration of cold ischemia before transplantation. Results: Average Medicare payments for renal-transplant recipients in the three years after transplantation increased from 80,807 for kidneys with six HLA mismatches between donor and recipient, a difference of 34 percent (P\u3c0.001). By three years after transplantation, the average Medicare payments were 74,997 for those with more than 36 hours (P\u3c0.001). In simulations, the assignment of cadaveric kidneys to recipients by a method that minimized HLA mismatching within a local geographic area (i.e., within one of the approximately 50 organ-procurement organizations, which cover widely varying geographic areas) produced the largest cost savings ($4,290 per patient over a period of three years) and the largest improvements in the graft-survival rate (2.3 percent) when the potential costs of longer cold-ischemia time were considered. Conclusions: Transplantation of better-matched cadaveric kidneys could have substantial economic advantages. In our simulations, HLA-based allocation of kidneys at the local level produced the largest estimated cost savings, when the duration of cold ischemia was taken into account. No additional savings were estimated to result from a national allocation program, because the additional costs of longer cold-ischemia time were greater than the advantages of optimizing HLA matching
Fully Frustrated Ising System on a 3D Simple Cubic Lattice: Revisited
Using extensive Monte Carlo simulations, we clarify the critical behaviour of
the 3 dimensional simple cubic Ising Fully Frustrated system. We find two
transition temperatures and two long range ordered phases. Within the present
numerical accuracy, the transition at higher temperature is found to be second
order and we have extracted the standard critical exponent using finite size
scaling method. On the other hand, the transition at lower temperature is found
to be first order. It is argued that entropy plays a major role on determining
the low temperature state.Comment: 14 pages 14 figures iop style include
Primary prostatic adenocarcinoma in a domestic short-haired cat
An 8-years-old, domestic short-haired cat was presented for constipation and symptoms referable to the lower urinary tract. A solid mass located in the caudal area of the abdomen was palpated. Abdominal ultrasonography, positive-contrast retrograde urethrocystography and total body computed tomography showed the presence of a prostatic neoformation occupying almost completely the pelvic cavity. The neoformation displaced dorsolaterally the descending colon and completely englobed the prostatic urethra, without apparent involvement of the urethral lumen. Histopathologic examination revealed a prostatic carcinoma. Neoplastic cells showed a moderate to intense cytoplasmatic expression of AE1/AE3, while no expression of cytokeratin 7 and Uroplakin III was observed. Topographical, histological and immunohistochemical findings were consistent with a diagnosis of primary adenocarcinoma of the prostate body
The cryogenic RWELL: a stable charge multiplier for dual-phase liquid-argon detectors
The operation of a cryogenic Resistive WELL (RWELL) in liquid argon vapor is
reported for the first time. It comprises a Thick Gas Electron Multiplier
(THGEM) structure coupled to a resistive Diamond-Like Carbon (DLC) anode
deposited on an insulating substrate. The multiplier was operated at cryogenic
temperature (90~K, 1.2~bar) in saturated argon vapor and characterized in terms
of charge gain and electrical stability. A comparative study with standard,
non-resistive THGEM (a.k.a LEM) and WELL multipliers, confirmed the RWELL
advantages in terms of discharge quenching - thus superior gain and stability
Tropomyosin flexibility modulates Ca2+ sensitivity of thin filament and affects tension relaxation in skeletal muscle myofibrils after troponin-tropomyosin removal and reconstitution
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