Neural Dynamics in Parkinsonian Brain:The Boundary Between Synchronized and Nonsynchronized Dynamics

Synchronous oscillatory dynamics is frequently observed in the human brain. We analyze the fine temporal structure of phase-locking in a realistic network model and match it with the experimental data from parkinsonian patients. We show that the experimentally observed intermittent synchrony can be generated just by moderately increased coupling strength in the basal ganglia circuits due to the lack of dopamine. Comparison of the experimental and modeling data suggest that brain activity in Parkinson's disease resides in the large boundary region between synchronized and nonsynchronized dynamics. Being on the edge of synchrony may allow for easy formation of transient neuronal assemblies

X-ray Binaries and Globular Clusters in Elliptical Galaxies

The X-ray emission from normal elliptical galaxies has two major components: soft emission from diffuse gas and harder emission from populations of accreting (low-mass) stellar X-ray binaries (LMXB). If LMXB populations are tied to the field stellar populations in galaxies, their total X-ray luminosities should be proportional to the optical luminosities of galaxies. However, recent ASCA and Chandra X-ray observations show that the global luminosities of LMXB components in ellipticals exhibit significant scatter at a given optical luminosity. This scatter may reflect a range of evolutionary stages among LMXB populations in ellipticals of different ages. If so, the ratio of the global LMXB X-ray luminosity to the galactic optical luminosity, L_LMXB/L_opt, may be used to determine when the bulk of stars were formed in individual ellipticals. To test this, we compare variations in L_LMXB/L_opt for LMXB populations in ellipticals to optically-derived estimates of stellar ages in the same galaxies. We find no correlation, implying that L_LMXB/L_opt variations are not good age indicators for ellipticals. Alternatively, LMXBs may be formed primarily in globular clusters (through stellar tidal interactions), rather than in the stellar fields of galaxies. Since elliptical galaxies exhibit a wide range of globular cluster populations for a given galaxian luminosity, this may induce a dispersion in the LMXB populations of ellipticals with similar optical luminosities. Indeed, we find that L_LMXB/L_opt ratios for LMXB populations are strongly correlated with the specific globular cluster frequencies in elliptical galaxies. This suggests that most LMXBs were formed in globular clusters.Comment: 5 pages, emulateapj5 style, 2 embedded EPS figures, to appear in ApJ Letter

Cortical oxygenation suggests increased effort during cognitive inhibition in ecstasy polydrug users

Background: It is understood that 3,4-methylenedioxymethamphetamine (ecstasy) causes serotonin dysfunction and deficits in executive functioning. When investigating executive function, functional neuroimaging allows the physiological changes underlying these deficits to be investigated. The present study investigated behavioural and brain indices of inhibition in ecstasy-polydrug users. Methods: Twenty ecstasy-polydrug users and 20 drug-naïve participants completed an inhibitory control task (Random Letter Generation (RLG)) while prefrontal haemodynamic response was assessed using functional near infrared spectroscopy (fNIRS). Results: There were no group differences on background measures including sleep quality and mood state. There were also no behavioural differences between the two groups. However, ecstasy-polydrug users displayed significant increases in oxygenated haemoglobin (oxy-Hb) from baseline compared to controls at several voxels relating to areas of the inferior right medial prefrontal cortex, as well the right and left dorsolateral prefrontal cortex. Regression analysis revealed that recency of ecstasy use was a significant predictor of oxy-Hb increase at two voxels over the right hemisphere after controlling for alcohol and cannabis use indices. Conclusion: Ecstasy-polydrug users show increased neuronal activation in the prefrontal cortex compared to non-users. This is taken to be compensatory activation/recruitment of additional resources to attain similar performance levels on the task, which may be reversible with prolonged abstinence

Double Neutron Star Systems and Natal Neutron Star Kicks

We study the four double neutron star systems found in the Galactic disk in terms of the orbital characteristics of their immediate progenitors and the natal kicks imparted to neutron stars. Analysis of the effect of the second supernova explosion on the orbital dynamics, combined with recent results from simulations of rapid accretion onto neutron stars lead us to conclude that the observed systems could not have been formed had the explosion been symmetric. Their formation becomes possible if kicks are imparted to the radio-pulsar companions at birth. We identify the constraints imposed on the immediate progenitors of the observed double neutron stars and calculate the ranges within which their binary characteristics (orbital separations and masses of the exploding stars) are restricted. We also study the dependence of these limits on the magnitude of the kick velocity and the time elapsed since the second explosion. For each of the double neutron stars, we derive a minimum kick magnitude required for their formation, and for the two systems in close orbits we find it to exceed 200km/s. Lower limits are also set to the center-of-mass velocities of double neutron stars, and we find them to be consistent with the current proper motion observations.Comment: 25 pages, 6 figs (9 parts), 4 tables, AASTeX, Accepted in Ap

Comparison of surface and column measurements of aerosol scattering properties over the western North Atlantic Ocean at Bermuda

Light scattering by size-resolved aerosols in near-surface air at Tudor Hill, Bermuda, was measured between January and June 2009. Vertical distributions of aerosol backscattering and column-averaged aerosol optical properties were characterized in parallel with a micro-pulse lidar (MPL) and an automated sun–sky radiometer. Comparisons were made between extensive aerosol parameters in the column, such as the lidar-retrieved extinction at 400 m and the aerosol optical depth (AOD), and scattering was measured with a surface nephelometer. Comparisons were also made for intensive parameters such as the Ångström exponent and calculations using AERONET(Aerosol Robotic Network)-derived aerosol physical parameters (size distribution, index of refraction) and Mie theory, and the ratio of submicron scattering to total scattering for size-segregated nephelometer measurements. In these comparisons the <i>r</i>² was generally around 0.50. Data were also evaluated based on back trajectories. The correlation between surface scattering and lidar extinction was highest for flows when the surface scattering was dominated by smaller particles and the flow had a longer footprint over land then over the ocean. The correlation of AOD with surface scatter was similar for all flow regimes. There was also no clear dependence of the atmospheric lapse rate, as determined from a nearby radiosonde station, on flow regime. The Ångström exponent for most flow regimes was 0.9–1.0, but for the case of air originating from North America, but with significant time over the ocean, the Ångström exponent was 0.57 ± 0.18. The submicron fraction of aerosol near the surface (<i>R</i>_sub-surf) was significantly greater for the flows from land (0.66 ± 0.11) than for the flows which spent more time over the ocean (0.40 ± 0.05). When comparing <i>R</i>_sub-surf and the column-integrated submicron scattering fraction, <i>R</i>_sub-col, the correlation was similar, <i>r</i>² = 0.50, but <i>R</i>_sub-surf was generally less than <i>R</i>_sub-col, indicating more large particles contributing to light scattering at the surface, contrary to conditions over continents and for polluted continental transport over the ocean. In general, though, the marginal correlations indicate that the column optical properties are weakly correlated with the surface optical measurements. Thus, if it is desired to associate aerosol chemical/physical properties with their optical properties, it is best to use optical and chemical/physical measurements with both collected at the surface or both collected in the column

The Intrinsic Origin of Spin Echoes in Dipolar Solids Generated by Strong Pi Pulses

In spectroscopy, it is conventional to treat pulses much stronger than the linewidth as delta-functions. In NMR, this assumption leads to the prediction that pi pulses do not refocus the dipolar coupling. However, NMR spin echo measurements in dipolar solids defy these conventional expectations when more than one pi pulse is used. Observed effects include a long tail in the CPMG echo train for short delays between pi pulses, an even-odd asymmetry in the echo amplitudes for long delays, an unusual fingerprint pattern for intermediate delays, and a strong sensitivity to pi-pulse phase. Experiments that set limits on possible extrinsic causes for the phenomena are reported. We find that the action of the system's internal Hamiltonian during any real pulse is sufficient to cause the effects. Exact numerical calculations, combined with average Hamiltonian theory, identify novel terms that are sensitive to parameters such as pulse phase, dipolar coupling, and system size. Visualization of the entire density matrix shows a unique flow of quantum coherence from non-observable to observable channels when applying repeated pi pulses.Comment: 24 pages, 27 figures. Revised from helpful referee comments. Added new Table IV, new paragraphs on pages 3 and 1

The landscape of gifted and talented education in England and Wales: How are teachers implementing policy?

This is an Author's Accepted Manuscript of an article published in Research Papers in Education, 27(2), 167-186, 2012, copyright Taylor & Francis, available online at: http://www.tandfonline.com/10.1080/02671522.2010.509514.This paper explores the evidence relating to how primary schools are responding to the ‘gifted and talented’ initiative in England and Wales. A questionnaire survey which invited both closed and open-ended responses was carried out with a national sample of primary schools. The survey indicated an increasing proportion of coordinators, compared with a survey carried out in 1996, were identifying their gifted and talented children as well as having associated school policies. However, the survey also highlighted a number of issues which need addressing if the initiative is to achieve its objective of providing the best possible educational opportunities for children. For example, it was found that a significant number of practitioners were not aware of the existence of the National Quality Standards for gifted and talented education, provided by the UK government in 2007, and the subject-specific criteria provided by the UK’s Curriculum Authority for identification and provision have been largely ignored. The process of identifying children to be placed on the ‘gifted and talented’ register seems haphazard and based on pragmatic reasons. Analysis of teachers’ responses also revealed a range of views and theoretical positioning held by them, which have implications for classroom practice. As the ‘gifted and talented’ initiative in the UK is entering a second decade, and yet more significant changes in policy are introduced, pertinent questions need to be raised and given consideration

Associative memory storing an extensive number of patterns based on a network of oscillators with distributed natural frequencies in the presence of external white noise

We study associative memory based on temporal coding in which successful retrieval is realized as an entrainment in a network of simple phase oscillators with distributed natural frequencies under the influence of white noise. The memory patterns are assumed to be given by uniformly distributed random numbers on $[0,2\pi)$ so that the patterns encode the phase differences of the oscillators. To derive the macroscopic order parameter equations for the network with an extensive number of stored patterns, we introduce the effective transfer function by assuming the fixed-point equation of the form of the TAP equation, which describes the time-averaged output as a function of the effective time-averaged local field. Properties of the networks associated with synchronization phenomena for a discrete symmetric natural frequency distribution with three frequency components are studied based on the order parameter equations, and are shown to be in good agreement with the results of numerical simulations. Two types of retrieval states are found to occur with respect to the degree of synchronization, when the size of the width of the natural frequency distribution is changed.Comment: published in Phys. Rev.

Supernova Kicks, Magnetic Braking, and Neutron-Star Binaries

We consider the formation of low-mass X-ray binaries containing accreting neutron stars via the helium-star supernova channel. The predicted relative number of short-period transients provides a sensitive test of the input physics in this process. We investigate the effect of varying mean kick velocities, orbital angular momentum loss efficiencies, and common envelope ejection efficiencies on the subpopulation of short-period systems, both transient and persistent. Guided by the thermal-viscous disk instability model in irradiation-dominated disks, we posit that short-period transients have donors close to the end of core-hydrogen burning. We find that with increasing mean kick velocity the overall short-period fraction, s, grows, while the fraction, r, of systems with evolved donors among short-period systems drops. This effect, acting in opposite directions on these two fractions, allows us to constrain models of LMXB formation through comparison with observational estimates of s and r. Without fine tuning or extreme assumptions about evolutionary parameters, consistency between models and current observations is achieved for a regime of intermediate average kick magnitudes of about 100-200 km/s, provided that (i) orbital braking for systems with donor masses in the range 1-1.5 solar masses is weak, i.e., much less effective than a simple extrapolation of standard magnetic braking beyond 1.0 solar mass would suggest, and (ii) the efficiency of common envelope ejection is low.Comment: 24 pages, AAATeX, accepted for publication in The Astrophysical Journa

Three-dimensional coherent X-ray diffraction imaging of a ceramic nanofoam: determination of structural deformation mechanisms

Ultra-low density polymers, metals, and ceramic nanofoams are valued for their high strength-to-weight ratio, high surface area and insulating properties ascribed to their structural geometry. We obtain the labrynthine internal structure of a tantalum oxide nanofoam by X-ray diffractive imaging. Finite element analysis from the structure reveals mechanical properties consistent with bulk samples and with a diffusion limited cluster aggregation model, while excess mass on the nodes discounts the dangling fragments hypothesis of percolation theory.Comment: 8 pages, 5 figures, 30 reference