Infecção por Giardia duodenalis e outros enteroparasitos em crianças com câncer e crianças de creche em Salvador, Bahia

Introdução: Crianças constituem um dos principais grupos de risco de infecções por Giardia duodenalis e outros enteroparasitos. A infecção é geralmente assintomática ou pode evoluir para diarreia aguda ou tornar-se crônica, resultando em perda de peso e retardo no crescimento. Em crianças com tumores malignos, a infecção parasitária pode seguir um curso severo ou mesmo resultar em morte. Objetivo: estabelecer a frequência de G. duodenalis e outros enteroparasitos em fezes de crianças com câncer e de crianças de creche. Metodologia: Amostras fecais foram coletadas de 70 pacientes portadores de câncer e 493 crianças de creche e submetidas às seguintes técnicas de diagnóstico: Baermann-Moraes e cultura de fezes em placa de ágar, flutuação em sulfato de zinco, sedimentação por centrifugação e coloração de Ziehl-Neelsen modificado. Resultados: A frequência de enteroparasitos em crianças com câncer e crianças de creche foi de 47,1% e 35,5%, respectivamente. Os parasitos patogênicos mais prevalentes em crianças com câncer foram Blastocystis hominis (11,4%), seguidos por Giardia duodenalis (8,6%). Nas crianças de creche a Giardia duodenalis foi o parasito patogênico significativamente (

Novel Human Parechovirus from Brazil

Human parechoviruses (HPeVs) were detected by reverse transcription–PCR in 16.1% of 335 stool samples from children <6 years of age with enteritis in Salvador, Brazil. Whole genome sequencing of 1 sample showed a novel HPeV that has been designated as HPeV8

Limitations of Probiotic Therapy in Acute, Severe Dehydrating Diarrhea

Ramos, Eduardo Antonio Gonçalves. “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”.Submitted by Ana Maria Fiscina Sampaio ([email protected]) on 2018-05-14T13:43:19Z No. of bitstreams: 1 Ramos EA Limitations of Probiotic Therapy in Acute.....pdf: 241722 bytes, checksum: 7e9b7fedbad8fab7d66c012c1db3d771 (MD5)Approved for entry into archive by Ana Maria Fiscina Sampaio ([email protected]) on 2018-05-14T13:58:58Z (GMT) No. of bitstreams: 1 Ramos EA Limitations of Probiotic Therapy in Acute.....pdf: 241722 bytes, checksum: 7e9b7fedbad8fab7d66c012c1db3d771 (MD5)Made available in DSpace on 2018-05-14T13:58:58Z (GMT). No. of bitstreams: 1 Ramos EA Limitations of Probiotic Therapy in Acute.....pdf: 241722 bytes, checksum: 7e9b7fedbad8fab7d66c012c1db3d771 (MD5) Previous issue date: 2003Pronex/CNPq (661086/1998-4), BrazilFederal University of Bahia. School of Medicine. Department of Pediatrics. Salvador, BA, BrazilFederal University of Bahia. School of Medicine. Department of Pediatrics. Salvador, BA, BrazilFederal University of Bahia. School of Medicine. Department of Pediatrics. Salvador, BA, BrazilFederal University of Bahia. School of Medicine. Department of Pediatrics. Salvador, BA, BrazilFederal University of Bahia. School of Medicine. Department of Pediatrics. Salvador, BA, BrazilFederal University of Bahia. School of Medicine. Department of Pediatrics. Salvador, BA, BrazilFederal University of Bahia. School of Medicine. Department of Pediatrics. Salvador, BA, BrazilFederal University of Bahia. School of Medicine. Department of Pediatrics. Salvador, BA, BrazilUniversity of Nebraska Medical Center. Omaha, Nebraska, U.S.AUniversity of Nebraska Medical Center. Omaha, Nebraska, U.S.ABackground: Recent studies have shown that probiotics, most commonly Lactobacillus GG, may be useful in treating acute gastroenteritis. However, beneficial effects appear to be limited to a modest decrease in the duration of diarrhea. No studies have evaluated this therapy in moderate to severe dehydrating diarrhea in a metabolic facility. Methods: Male children less than 2 years of age were admitted to a metabolic unit of the Department of Pediatrics at the Federal University of Bahia, Brazil, with moderate dehydration and were randomized in a double-blind, placebo-controlled fashion. Oral rehydration solution (ORS) was administered per protocol and either placebo or Lactobacillus GG was given in combination with the ORS. Output of urine, stool, and vomitus was recorded along with stool weight, nude body weight, and standard laboratory assessments for hydration. Results: There was no significant reduction in diarrhea duration and stool output in the Lactobacillus GG group. However, Kaplan-Meier survival analysis demonstrated that, even in moderate to severe diarrhea, resolution of the illness occurred so rapidly, that statistically significant benefits of probiotic therapy could not be demonstrated. Conclusion: Our data implies that colonization must occur before benefits of probiotics can be realized. Probiotics are, therefore, likely to be of limited benefit in treating diarrheal illnesses of short duration such as viral enteritis. The beneficial effects of probiotics may be limited to prophylactic usage in high-risk populations

Segmental absence of intestinal musculature - presentation in a 10-year-old boy with an extensive involved segment

Freitas, Luiz Antonio Rodrigues de “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”.Submitted by Ana Maria Fiscina Sampaio ([email protected]) on 2017-07-12T17:06:41Z No. of bitstreams: 1 Athanazio DA Segmental Absence of IntestinalMusculature.pdf: 3557207 bytes, checksum: ee89eb17976189d246217dc021b2e4d4 (MD5)Approved for entry into archive by Ana Maria Fiscina Sampaio ([email protected]) on 2017-07-12T17:18:13Z (GMT) No. of bitstreams: 1 Athanazio DA Segmental Absence of IntestinalMusculature.pdf: 3557207 bytes, checksum: ee89eb17976189d246217dc021b2e4d4 (MD5)Made available in DSpace on 2017-07-12T17:18:13Z (GMT). No. of bitstreams: 1 Athanazio DA Segmental Absence of IntestinalMusculature.pdf: 3557207 bytes, checksum: ee89eb17976189d246217dc021b2e4d4 (MD5) Previous issue date: 2015Federal University of Bahia. Salvador, BA, Brasil.Hospital Universitário Professor Edgard Santos. Salvador, BA, Brasil.Federal University of Bahia. Faculty of Medicine. Salvador, BA, Brasil.Federal University of Bahia. Faculty of Medicine. Salvador, BA, Brasil.Federal University of Bahia. Faculty of Medicine. Salvador, BA, Brasil.Federal University of Bahia. Salvador, BA, Brasil.Federal University of Bahia. Salvador, BA, Brasil.Segmental absence of the intestinal musculature is a rare cause of acute abdomen most likely associated with intestinal perforation and sepsis in neonates and adults. We present a case of a 10-year-old boy who developed acute abdomen and was treated with right hemicolectomy and partial resection of the ileum. The ileum showed a 20-cm-long stenotic segment showing prominent thinning of the intestinal wall. This case occurred in an older child, which appears to be rare when comparing the literature. The bowel defect was also the largest described to date, indicating the potential effect of an atonic segment leading to obstructive disease