An HST/COS legacy survey of intervening SiIII absorption in the extended gaseous halos of low-redshift galaxies

Doubly ionized silicon (SiIII) is a powerful tracer of diffuse ionized gas inside and outside of galaxies. It can be observed in the local Universe in ultraviolet (UV) absorption against bright extragalactic background sources. We here present an extensive study of intervening SiIII-selected absorbers and their relation to the circumgalactic medium (CGM) of galaxies at low redshift (z<=0.1), based on the analysis of UV absorption spectra along 303 extragalactic lines of sight obtained with the Cosmic Origins Spectrograph (COS) on board the Hubble Space Telescope (HST). Along a total redshift path of Dz=24 we identify 69 intervening SiIII systems that all show associated absorption from other low and high ions. We derive a bias-corrected number density of dN/dz(SiIII)=2.5 for absorbers with column densities log N(SiIII)>12.2. We develop a geometrical model for the absorption-cross section of the CGM around the local galaxy population and find excellent agreement between the model predictions and the observations. We further compare redshifts and positions of the absorbers with that of ~64,000 galaxies using archival galaxy-survey data. For the majority of the absorbers we identify possible host galaxies within 300 km/s of the absorbers and derive impact parameters rho<200 kpc, demonstrating that the spatial distributions of SiIII absorbers and galaxies are highly correlated. Our study indicates that the majority of SiIII-selected absorbers in our sample trace the CGM of nearby galaxies within their virial radii at a typical covering fraction of ~70 per cent. From a detailed ionization model we estimate that diffuse gas in the CGM around galaxies, as traced by SiIII, contains substantially more baryonic mass than their neutral interstellar medium.Comment: 32 pages, 17 figures; final version accepted for publication in A&

The rapid onset of stellar bars in the baryon-dominated centers of disk galaxies

Recent observations of high-redshift galactic disks ($z\approx 1-3$) show a strong negative trend in the dark matter fraction $f_{DM}$ with increasing baryonic surface density. For this to be true, the inner baryons must dominate over dark matter in early massive galaxies, as observed in the Milky Way today. If disks are dominant at early times, we show that stellar bars form promptly within these disks, leading to a high bar fraction at early times. New JWST observations provide the best evidence to date for mature stellar bars in this redshift range. The disk mass fraction $f_{disk}$ within $R_s=2.2 R_{disk}$ is the dominant factor in determining how rapidly a bar forms. Using 3D hydro simulations of halo-disk-bulge galaxies, we confirm the "Fujii relation" for the exponential dependence of the bar formation time $\tau_{bar}$ as a function of $f_{disk}$. For $f_{disk} > 0.3$, the bar formation time declines exponentially fast with increasing $f_{disk}$. This relation is a challenge to simulators - barred models with inadequate resolution fall off this curve. Instead of Fujii's arbitrary threshold for when a bar forms, for the first time, we exploit the exponential growth timescale associated with a positive feedback cycle as the bar emerges from the underlying disk. A modified, mass-dependent trend is observed for halos relevant to systems at cosmic noon ($10.5 < \log M_{halo} < 12$), where the bar onset is slower for higher mass halos at a fixed $f_{disk}$. If baryons dominate over dark matter within $R \approx R_s$, we predict that a high fraction of bars will be found in high-redshift disks long before $z = 1$. Due to its widespread use in simulations, we investigate the Efstathiou-Lake-Negroponte criterion for bar instability: this sub-optimal parameter is inversely related to $f_{disk}$, with a secondary dependence on $M_{halo}$.Comment: 27 pages, 8 figures, 1 table - Astrophysical Journal, accepted (9 March 2023

Prospective dark matter annihilation signals from the Sagittarius Dwarf Spheroidal

The Sagittarius Dwarf Spheroidal galaxy (Sgr) is investigated as a target for dark matter (DM) annihilation searches utilizing J-factor distributions calculated directly from a high-resolution hydrodynamic simulation of the infall and tidal disruption of Sgr around the Milky Way. In contrast to past studies, the simulation incorporates DM, stellar and gaseous components for both the Milky Way and the Sgr progenitor galaxy. The simulated distributions account for significant tidal disruption affecting the DM density profile. Our estimate of the J-factor value for Sgr, JSgr = 1.48 × 1010 M2☉ kpc−5 (6.46 × 1016 GeV cm−5), is significantly lower than found in prior studies. This value, while formally a lower limit, is likely close to the true J-factor value for Sgr. It implies a DM cross-section incompatibly large in comparison with existing constraints would be required to attribute recently observed gamma-ray emission from Sgr to DM annihilation. We also calculate a J-factor value using a NFW profile fitted to the simulated DM density distribution to facilitate comparison with past studies. This NFW J-factor value supports the conclusion that most past studies have overestimated the dark matter density of Sgr on small scales. This, together with the fact that the Sgr has recently been shown to emit gamma-rays of astrophysical origin, complicate the use of Sgr in indirect DM detection searches

Striatal interneurons in dissociated cell culture

In addition to the well-characterized direct and indirect projection neurons there are four major interneuron types in the striatum. Three contain GABA and either parvalbumin, calretinin or NOS/NPY/somatostatin. The fourth is cholinergic. It might be assumed that dissociated cell cultures of striatum (typically from embryonic day E18.5 in rat and E14.5 for mouse) contain each of these neuronal types. However, in dissociated rat striatal (caudate/putamen, CPu) cultures arguably the most important interneuron, the giant aspiny cholinergic neuron, is not present. When dissociated striatal neurons from E14.5 Sprague–Dawley rats were mixed with those from E18.5 rats, combined cultures from these two gestational periods yielded surviving cholinergic interneurons and representative populations of the other interneuron types at 5 weeks in vitro. Neurons from E12.5 CD-1 mice were combined with CPu neurons from E14.5 mice and the characteristics of striatal interneurons after 5 weeks in vitro were determined. All four major classes of interneurons were identified in these cultures as well as rare tyrosine hydroxylase positive interneurons. However, E14.5 mouse CPu cultures contained relatively few cholinergic interneurons rather than the nearly total absence seen in the rat. A later dissection day (E16.5) was required to obtain mouse CPu cultures totally lacking the cholinergic interneuron. We show that these cultures generated from two gestational age cells have much more nearly normal proportions of interneurons than the more common organotypic cultures of striatum. Interneurons are generated from both ages of embryos except for the cholinergic interneurons that originate from the medial ganglionic eminence of younger embryos. Study of these cultures should more accurately reflect neuronal processing as it occurs in the striatum in vivo. Furthermore, these results reveal a procedure for parallel culture of striatum and cholinergic depleted striatum that can be used to examine the function of the cholinergic interneuron in striatal networks

The GALAH+ Survey : Third Data Release

© 2021 The Author(s) Published by Oxford University Press on behalf of the Royal Astronomical Society. This is the accepted manuscript version of an article which has been published in final form at https://doi.org/10.1093/mnras/stab1242The ensemble of chemical element abundance measurements for stars, along with precision distances and orbit properties, provides high-dimensional data to study the evolution of the Milky Way. With this third data release of the Galactic Archaeology with HERMES (GALAH) survey, we publish 678 423 spectra for 588 571 mostly nearby stars (81.2% of stars are within 75 stellar clusters. We derive stellar parameters $T_\text{eff}$, $\log g$, [Fe/H], $v_\text{mic}$, $v_\text{broad}$ & $v_\text{rad}$ using our modified version of the spectrum synthesis code Spectroscopy Made Easy (SME) and 1D MARCS model atmospheres. We break spectroscopic degeneracies in our spectrum analysis with astrometry from $Gaia$ DR2 and photometry from 2MASS. We report abundance ratios [X/Fe] for 30 different elements (11 of which are based on non-LTE computations) covering five nucleosynthetic pathways. We describe validations for accuracy and precision, flagging of peculiar stars/measurements and recommendations for using our results. Our catalogue comprises 65% dwarfs, 34% giants, and 1% other/unclassified stars. Based on unflagged chemical composition and age, we find 62% young low-$\alpha$, 9% young high-$\alpha$, 27% old high-$\alpha$, and 2% stars with $\mathrm{[Fe/H]} \leq -1$. Based on kinematics, 4% are halo stars. Several Value-Added-Catalogues, including stellar ages and dynamics, updated after $Gaia$ eDR3, accompany this release and allow chrono-chemodynamic analyses, as we showcase.Peer reviewe

Country-level gender inequality is associated with structural differences in the brains of women and men

男女間の不平等と脳の性差 --男女間の不平等は脳構造の性差と関連する--. 京都大学プレスリリース. 2023-05-10.Gender inequality across the world has been associated with a higher risk to mental health problems and lower academic achievement in women compared to men. We also know that the brain is shaped by nurturing and adverse socio-environmental experiences. Therefore, unequal exposure to harsher conditions for women compared to men in gender-unequal countries might be reflected in differences in their brain structure, and this could be the neural mechanism partly explaining women’s worse outcomes in gender-unequal countries. We examined this through a random-effects meta-analysis on cortical thickness and surface area differences between adult healthy men and women, including a meta-regression in which country-level gender inequality acted as an explanatory variable for the observed differences. A total of 139 samples from 29 different countries, totaling 7, 876 MRI scans, were included. Thickness of the right hemisphere, and particularly the right caudal anterior cingulate, right medial orbitofrontal, and left lateral occipital cortex, presented no differences or even thicker regional cortices in women compared to men in gender-equal countries, reversing to thinner cortices in countries with greater gender inequality. These results point to the potentially hazardous effect of gender inequality on women’s brains and provide initial evidence for neuroscience-informed policies for gender equality

GASKAP-HI pilot survey science I: ASKAP zoom observations of Hi emission in the Small Magellanic Cloud

We present the most sensitive and detailed view of the neutral hydrogen (HI) emission associated with the Small Magellanic Cloud (SMC), through the combination of data from the Australian Square Kilometre Array Pathfinder (ASKAP) and Parkes (Murriyang), as part of the Galactic Australian Square Kilometre Array Pathfinder (GASKAP) pilot survey. These GASKAP-HI pilot observations, for the first time, reveal HI in the SMC on similar physical scales as other important tracers of the interstellar medium, such as molecular gas and dust. The resultant image cube possesses an rms noise level of 1.1K (1.6 mJy beam(-1)) per 0.98 km s(-1) spectral channel with an angular resolution of 30" (similar to 10 pc). We discuss the calibration scheme and the custom imaging pipeline that utilises a joint deconvolution approach, efficiently distributed across a computing cluster, to accurately recover the emission extending across the entire similar to 25 deg(2) field-of-view. We provide an overview of the data products and characterise several aspects including the noise properties as a function of angular resolution and the represented spatial scales by deriving the global transfer function over the full spectral range. A preliminary spatial power spectrum analysis on individual spectral channels reveals that the power law nature of the density distribution extends down to scales of 10 pc. We highlight the scientific potential of these data by comparing the properties of an outflowing high-velocity cloud with previous ASKAP+Parkes HI test observations

BacHBerry: BACterial Hosts for production of Bioactive phenolics from bERRY fruits

BACterial Hosts for production of Bioactive phenolics from bERRY fruits (BacHBerry) was a 3-year project funded by the Seventh Framework Programme (FP7) of the European Union that ran between November 2013 and October 2016. The overall aim of the project was to establish a sustainable and economically-feasible strategy for the production of novel high-value phenolic compounds isolated from berry fruits using bacterial platforms. The project aimed at covering all stages of the discovery and pre-commercialization process, including berry collection, screening and characterization of their bioactive components, identification and functional characterization of the corresponding biosynthetic pathways, and construction of Gram-positive bacterial cell factories producing phenolic compounds. Further activities included optimization of polyphenol extraction methods from bacterial cultures, scale-up of production by fermentation up to pilot scale, as well as societal and economic analyses of the processes. This review article summarizes some of the key findings obtained throughout the duration of the project