1,246 research outputs found

    Aspects concerning the elaboration of the questionnaires used in the marketing research

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    This study brings up the problems of the various questionnaires type applied in the study of market phenomena and processes and it shows the relevance of the possibilities the elaboration of the questionnaires brings in the process of achieving many category of information as well as the exigencies that should be considered when a certain type of questionnaire is selected. All these considerations should be put, of course, in the methodological and organizational general context of the planned statistical survey, in accordance with the recommendations of the theory and practice of specialty.questionnaire, marketing research, market survey

    Relaţia dintre anumite caracteristici morfologice şi producţie la fasolea urcătoare ecologică

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    The “components of yield” approach has been used widely to explain variations in the yield of grain legumes. The study has been conducted at Vegetable Research and Development Station (VRDS Buzau), under the normal testing conditions of 2018. The biological material was represented by 12 genotypes from the climbing beans(Phaseolus vulgarisL.) collectionof the Physiology, Agro-chemistry and Organic Crops Laboratory. A significant genetic variability has been found between climbing bean genotypes, for all indicators which have been analyzed. Some elements which define the pod architecture, the thickness and width have had a significant positive influence on yield indexes for climbing bean genotypes. Two lines of the climbing beans collection(L49M şi L6U) at VRDS Buzau have been identified with a very good performance in yield index on climatic conditions of 2018. These varieties could be used in the breeding program in agro-ecological system for obtaining new cultivars with a good performance in yield

    Cardiac structural and functional profile of patients with delayed QRS transition zone and sudden cardiac death

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    Delayed QRS transition zone in the precordial leads of the 12-lead electrocardiogram (ECG) has been recently associated with increased risk of sudden cardiac death (SCD), but the underlying mechanisms are unknown. We correlated echocardiographic findings with ECG and clinical characteristics to investigate how alterations in cardiac structure and function contribute to this risk marker. From the ongoing population-based Oregon Sudden Unexpected Death Study (catchment population similar to 1 million), SCD cases with prior ECG available (n = 627) were compared with controls (n = 801). Subjects with delayed transition at V-5 or later were identified, and clinical and echocardiographic patterns associated with delayed transition were analysed. Delayed transition was present in 31% of the SCD cases and 17% of the controls. These subjects were older and more likely to have cardiovascular risk factors and history of myocardial infarction. Delayed transition was associated with increased left ventricular (LV) mass (122.7 +/- 40.2 vs. 102.9 +/- 33.7 g/m(2); P <0.001), larger LV diameter (53.3 +/- 10.4 vs. 49.2 +/- 8.0 mm; P <0.001), and lower LV ejection fraction (LVEF) (46.4 +/- 15.7 vs. 55.6 +/- 12.5%; P <0.001). In multivariate analysis, delayed transition was independently associated with myocardial infarction, reduced LVEF, and LV hypertrophy. The association between delayed transition and SCD was independent of the LVEF (OR 1.57; 95% CI 1.04-2.38; P = 0.032). The underpinnings of delayed QRS transition zone extend beyond previous myocardial infarction and reduced LVEF. Since the association with sudden death is independent of these factors, this novel marker of myocardial electrical remodelling should be explored as a potential risk predictor of SCD.Peer reviewe

    Experimental and Calculated Vibrational Circular Dichroism Spectra of an Iminosugar Molecule: (2R, 3R, 4R) 1,4-dideoxy-1,4-imino-D-arabinitol Hydrochloride

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    The first vibrational circular dichroism (VCD) measurement of a biologically important iminosugar, (2R, 3R, 4R) 1,4-dideoxy-1,4-imino-D-arabinito

    Technologies Used in Medical Rehabilitation: A Systematic Review Regarding the Applicability of Rehabilitation Technologies in Certain Medical Domains

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    This article aims to investigate and explore present rehabilitation technology.  Through the accumulated results of this review, we will summarise the support and benefits that the emergence of technologies in medicine provides.  The primary objective of this study is to demonstrate how patient rehabilitation is evolving compared to traditional rehabilitation.  The initial search identified 113 titles in the databases; 18 duplicate articles were removed automatically.  The remaining 95 articles were examined by title and abstract, which resulted in the elimination of 59 studies.  The full texts of the remaining 36 articles were read and evaluated; nine articles were excluded because they did not satisfy the inclusion criteria established for this study.  At the evaluation stage, nine studies were thrown out because they did not fit into the medical fields that the research was looking into or because there was not enough data and information to analyse or rate the results.  Other studies were excluded from the full-text evaluation because the study sample was not specified.  Technology integration into rehabilitation presents obstacles such as high costs and limited accessibility.  Researchers, medicinal professionals, and the technology industry must work together to develop more effective and cost-effective solutions.  Nevertheless, these obstacles pale in comparison to the patient benefits of technology.  In order to maximise the benefits and surmount the current challenges, it will be necessary to continue the research and development of these technologies in the future.</p

    Left Ventricular Geometry and Risk of Sudden Cardiac Arrest in Patients With Severely Reduced Ejection Fraction

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    Background-Recent reports indicate that specific left ventricular (LV) geometric patterns predict recurrent ventricular arrhythmias in patients with implantable cardioverter-defibrillators and reduced left ventricular ejection fraction (LVEF). However, this relationship has not been evaluated among patients at risk of sudden cardiac arrest (SCA) in the general population. Methods and Results-Adult SCA cases from the Oregon Sudden Unexpected Death Study were compared with geographic controls with no prior history of SCA. Archived echocardiograms performed closest and prior to the SCA event were reviewed. LV geometry was defined as normal (normal LV mass index [LVMI] and relative wall thickness [RWT]), concentric remodeling (normal LVMI and increased RWT), concentric hypertrophy (increased LVMI and RWT), or eccentric hypertrophy (increased LVMI and normal RWT). Analysis was restricted to those with LVEF Conclusions-Eccentric LV hypertrophy was independently associated with increased risk of SCA in subjects with EFPeer reviewe

    Romanian Organic and Conventional Red Grapes Vineyards as Potential Sources of High Value-Added Products, in a Circular Economy Approach

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    The use of natural ingredients with active functions has been intensively studied in the last years, as a consequence to consumer preferences for organic products. Application of circular economy principles determined a significant research activity in the viticulture field. The use or re-use of vines parts for so-called nutraceuticals or other consumer-goods applications, are basically centered on their phytochemical and microbiological characterization. Eurostat updates ranks Romania fifth among the EU member states, with a total area under vines of 183,717 hectares. Characterization of four Vitis vinifera L. varieties, out of which one pure Romanian variety (Feteasca Neagra), cultivated in organic and conventional vineyards, together with pedoclimatic conditions have been provided. Data on phytochemical parameters and antimicrobial activity of extracts obtained from different anatomic parts of grapes were included. Analytical protocols and techniques applied were presented, together with data and results interpretation. Several chemometric algorithms have been used as complementary tools for interpretation of the instrumental analytical data

    Studies on obtaining active dry wine yeast using different nitrogen sources

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    Most of research on wine microbiology has concentrated on Saccharomyces yeasts for development of starter cultures, especially on Sacch. cerevisiae. As the importance of the role of S. cerevisiae in winemaking has been established, the number of wine yeast strains available in the world market for use as winemaking starters grew in the last years. The upstream process of producing Sacch. cerevisiae biomass on a culture medium based on sugar was performed by testing different sources of inorganic and organic nitrogen (yeast extract and monoammonium phosphate) in submerged fermentations using a Biostat B plus bioreactor (4L working volume). The upstream parameters have been monitored on-line (oxygen flow; pH around 4.35; temperature 300C; stirring rate 250 rpm) and off-line (total soluble dry matter; pH). The biomass obtained after the downstream process has been dried through freeze-drying. Through the combination of two carbon sources as yeast extract (0.7%) and monoammonium phosphate 10.71 g/L dry cell weight (DCW) has been obtained, compared with 9.6 g/L DCW in the case of the fermentation without monoammonium phosphate. From the economic reasons, the monoammonium phosphate as an inorganic nitrogen form has been excluded from the experiments. Finally, the higher content of dry yeast biomass (14.43 g/L DCW) was obtained when 11% yeast extract as the only nitrogen source has been added at the fermentation media

    Identification of a Sudden Cardiac Death Susceptibility Locus at 2q24.2 through Genome-Wide Association in European Ancestry Individuals

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    Sudden cardiac death (SCD) continues to be one of the leading causes of mortality worldwide, with an annual incidence estimated at 250,000–300,000 in the United States and with the vast majority occurring in the setting of coronary disease. We performed a genome-wide association meta-analysis in 1,283 SCD cases and >20,000 control individuals of European ancestry from 5 studies, with follow-up genotyping in up to 3,119 SCD cases and 11,146 controls from 11 European ancestry studies, and identify the BAZ2B locus as associated with SCD (P = 1.8×10−10). The risk allele, while ancestral, has a frequency of ∼1.4%, suggesting strong negative selection and increases risk for SCD by 1.92–fold per allele (95% CI 1.57–2.34). We also tested the role of 49 SNPs previously implicated in modulating electrocardiographic traits (QRS, QT, and RR intervals). Consistent with epidemiological studies showing increased risk of SCD with prolonged QRS/QT intervals, the interval-prolonging alleles are in aggregate associated with increased risk for SCD (P = 0.006)
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