Denial of Access to the Lloyd Aquifer: The Impossibility of Overcoming the Lloyd Moratorium

This article will discuss the Lloyd Moratorium as it exists today. Section two of this article discusses the geological framework, hydrogeology, pumpage, and saltwater intrusion of the Long Island Aquifer System. Section three discusses the history, development, and agency interpretation of the moratorium. Section four analyzes the likelihood of a community being granted a permit to drill a new well and explores the possibility of a particular community on Long Island with a contaminated aquifer obtaining a permit to drill into the Lloyd Aquifer. Section five concludes by proposing that the New York State Department of Environmental Conservation should promulgate regulations that provide a clear interpretation of the moratorium’s conditions

The history of West Hartford, Connecticut, for the third grade.

Thesis (Ed.M.)--Boston Universit

Influence of temper condition on the nonlinear stress-strain behavior of boron-aluminum

The influence of temper condition on the tensile and compressive stress-strain behavior for six boron-aluminum laminates was investigated. In addition to monotonic tension and compression tests, tension-tension, compression-compression, and tension--compression tests were conducted to study the effects of cyclic loading. Tensile strength results are a function of the laminate configuration; unidirectional laminates were affected considerably more than other laminates with some strength values increasing and others decreasing

Construction and measurements of a vacuum-swing-adsorption radon-mitigation system

Long-lived alpha and beta emitters in the $^{222}$Rn decay chain on (and near) detector surfaces may be the limiting background in many experiments attempting to detect dark matter or neutrinoless double-beta decay, and in screening detectors. In order to reduce backgrounds from radon-daughter plate-out onto the wires of the BetaCage during its assembly, an ultra-low-radon cleanroom is being commissioned at Syracuse University using a vacuum-swing-adsorption radon-mitigation system. The radon filter shows ~20$\times$ reduction at its output, from 7.47$\pm$0.56 to 0.37$\pm$0.12 Bq/m$^3$, and the cleanroom radon activity meets project requirements, with a lowest achieved value consistent with that of the filter, and levels consistently < 2 Bq/m$^3$.Comment: 5 pages, 3 figures, Proceedings of Low Radioactivity Techniques (LRT) 2013, Gran Sasso, Italy, April 10-12, 201

AAV8 capsid variable regions at the two-fold symmetry axis contribute to high liver transduction by mediating nuclear entry and capsid uncoating

AbstractAdeno-associated virus serotype 8 (AAV8) is a promising vector for liver-directed gene therapy. Although efficient uncoating of viral capsids has been implicated in AAV8׳s robust liver transduction, much about the biology of AAV8 hepatotropism remains unclear. Our study investigated the structural basis of AAV8 liver transduction efficiency by constructing chimeric vector capsids containing sequences derived from AAV8 and AAV2 – a highly homologous yet poorly hepatotropic serotype. Engineered vectors containing capsid variable regions (VR) VII & IX from AAV8 in an AAV2 backbone mediated near AAV8-like transduction in mouse liver, with higher numbers of chimeric genomes detected in whole liver cells and isolated nuclei. Interestingly, chimeric capsids within liver nuclei also uncoated similarly to AAV8 by 6 weeks after administration, in contrast with AAV2, of which a significantly smaller proportion were uncoated. This study links specific AAV capsid regions to the transduction ability of a clinically relevant AAV serotype

Structures and materials technology issues for reusable launch vehicles

Projected space missions for both civil and defense needs require significant improvements in structures and materials technology for reusable launch vehicles: reductions in structural weight compared to the Space Shuttle Orbiter of up to 25% or more, a possible factor of 5 or more increase in mission life, increases in maximum use temperature of the external surface, reusable containment of cryogenic hydrogen and oxygen, significant reductions in operational costs, and possibly less lead time between technology readiness and initial operational capability. In addition, there is increasing interest in hypersonic airbreathing propulsion for launch and transmospheric vehicles, and such systems require regeneratively cooled structure. The technology issues are addressed, giving brief assessments of the state-of-the-art and proposed activities to meet the technology requirements in a timely manner

Tree Climbing Limb Saw

This document is the comprehensive report for the Tree Climbing Limb Saw Senior Project. The purpose of the Tree Climbing Limb Saw project, completed by mechanical engineers Andrew Bray, Aimee Chiem, Drew Robles, and Parker Tenney, is to remove low-hanging branches (\u3c15 \u3eft) to prevent forest fires from travelling up into the canopy, where wind can carry embers for miles. An RC car was heavily modified to create a solution for this problem. A chainsaw was also mounted to deal with the cutting part of the problem. Creating a project which aims to solve this problem is a great step towards innovation reaching the wildfire sector. With increased innovation in the field, wildfires may become easier to control. This comprehensive report includes the initial Scope of Work report of this project, followed by the Preliminary Design Review, Critical Design Review, and Final Design Review Report