Plasma neutrophil gelatinase-associated lipocalin levels and the hemogram levels and their relationship to disease severity in OCD

Objective: The release of neutrophil gelatinase-associated lipocalin (NGAL), involved with immunity regulation, is a neuromediators. The number of studies related to disease-hemogram in Obsessive Compulsive Disorder (OCD) is low. The aim of our study was to measure the blood NGAL levels and hemogram results in first diagnosis of OCD and to evaluate the relationship between the findings and disease severity. Methods: A total of 28,050 patients, who were presented to psychiatry outpatient clinic between January 2018 and January 2020 were evaluated. Thirty-two patients, for who were diagnosed first-episode OCD and agreed to participate the study were examined with using the Yale Brown Obsession Compulsion Scale (Y-BOCS), to measure the peripheral blood NGAL levels and hemogram results, and related to immune regulation the total leukocyte counts and neutrophil granulocyte percent-age (NEU%); and the C reactive protein (CRP) levels were recorded. Results: In the comparison of the first-episode OCD patients, a significant difference was found between the NEU% and CRP values while was not found between the blood NGAL levels. Although there was no significant difference between the Y-BOCS scores and blood NGAL levels, the Y-BOCS scores increased as the blood hemoglobin and hematocrit values decreased. Conclusion: This is the first study on this topic in the literature, indicated that although there was an increase in some inflammatory mediators in first-episode OCD patients, there was no significant increase between plasma NGAL levels and OCD severity; and that increasing OCD severity did have an effect on blood hemoglobin and hematocrit levels

Evaluation of sleep-wakefulness disorders in healthcare professionals working at a university hospital during COVID-19

BACKGROUND: The COVID-19 pandemic has impaired the sleep-wakefulness cycle especially of healthcare professionals (HP). Sleep is affected by many factors and preventable risk factors protect HP from sleep disorders. To evaluate sleep quality and sleep disorders in HP working to gain insight risk factors and to raise awareness about working risk groups. MATERIAL AND METHODS: The study population consisted of a total of 1190 HP employed at a hospital during the COVID-19 pandemic. From this population, a sample of 110 HP was selected based on reported only complaints of sleep. A sociodemographic data form and subjective sleep-wakefulness scales were applied. Sleep disorder was evaluated according to the ICSD-3. RESULTS: Most of the participants were female. It was observed that 67.3%of the HP had disturbed sleep quality, and that nurses and medical secretaries had more complaints compared to doctors. Insomnia disorders was the most common disorder among the participants. Cases of insomnia disorders were found to be 15.477 times higher among those who had a history of mental disorders in their families, smoking was shown to have the most negative effect on biological rhythm, and married people experienced more sleepiness during the day. CONCLUSIONS During the COVID-19 pandemic, ancillary health staff is at greater risk of experiencing deterioration of sleep quality and insomnia disorders. Female, being married, cigarette smoking, and family history of psychiatric disorders were correlated with the development of sleep complaints

Maternal Gestational Diabetes and Early Childhood Obesity: A Retrospective Cohort Study

WOS: 000589774400001PubMed: 33146559Background: Recently, childhood obesity has become one of the most serious public health problems in the world. Gestational diabetes mellitus (GDM) is considered a risk factor for childhood overweight and obesity. the study aimed at investigating the relationship between maternal GDM and childhood obesity in children aged from 1 to 3 years. Methods: in this retrospective cohort study, 237 GDM and 296 non-GDM mothers and their offspring who were followed up by Family Medicine Clinics in Rize province of Turkey were assessed. World Health Organization (WHO) criteria were used for the diagnosis of maternal GDM. Crude and adjusted logistic regression models were calculated for the association of gestational diabetes and childhood overweight/obesity. Gender and age-specific percentile tables were used for the categorization of BMI. Results: Statistical analysis carried out with adjustment for potential confounders (mother's age, educational status, smoking status, BMI, gestational weight gain, children's gender, and gestational birth weight) provided results with an odds ratio of 2.99; 95% CI 1.14-7.94 and 7.77; 95% CI 1.92-31.37 for the impact of gestational diabetes on childhood overweight and obesity at 2 and 3 years of age, respectively. Conclusions: This study found evidence for maternal GDM to cause the risk of early childhood obesity. Therefore, proper intervention strategies are required for this high-risk population

FALLS AND AWARENESS ABOUT FALLS IN ELDERLY AND DEFINING THEIR RELATIONS WITH QUALITY OF LIFE

Uner, Sarp/0000-0002-9880-8811; Telatar, Gokhan/0000-0002-3261-3464; Bicer, Burcu Kucuk/0000-0002-5615-264XWOS: 000446617400606[No abstract available

Following-up the long-term efficacy of hepatitis B vaccine in immunization of risky occupational groups

Hepatitis B virus (HBV) infection is very common and contagious public health problem with serious pathological consequences (i.e. chronic liver failure, cirrhosis, hepatocellular carcinoma). Since HBV is frequently reported as an occupational disease factor, exposure risk is a concerning problem especially in health-care personnel. The aim of this study is to evaluate the time-dependent change of anti-HBs titer levels in various occupational groups. In the study, 2512 cases from 12 different occupational groups with HBV exposure risk who were applied to Ankara Occupational and Environmental Diseases Hospital Occupational Diseases Clinic for medical screening between October 2012 and November 2018 were examined and assessed. Protective titer levels of anti-HBs were determined in 64.8% people in the risky occupational group. HBV seropositivity rates were found as highest in dentists (94.5%) and lowest in kitchen workers (40.1%). The protective anti-HBs titer level in healthcare workers (i.e. dentist, x-ray technician, supporter healthcare personnel) was found to be 89.4%. Those with anti-HBs titer protective level (≥ 10 mIU / ml) were defined as Group-1 (n=1631), and those with Ab level ( [Med-Science 2020; 9(2.000): 443-9

Purchasing power parity hypothesis: mixed evidence from eastern europe emerging markets

This paper investigates whether the purchasing power parity (PPP) hypothesis holds in the Czech Republic, Hungary, and Poland by considering currencies of their five largest trading partners. We employ eight panel unit root tests that can be arranged in groups by cross-section independence or dependence. Empirical findings show that the stochastic behavior of real exchange rates in the Czech Republic and Poland is not a mean reversion, and the PPP condition does not hold for them. However, we obtain mixed empirical evidence in Hungary. Limited evidence is found for validity of the PPP hypothesis among currencies of Hungary's largest trading partners