1963 Clinic Yearbook

The Clinic is the yearbook of the Sidney Kimmel Medical College (formerly Jefferson Medical College) at Thomas Jefferson University

Creating Connections to Landscapes and Cultures through the Plants of Montana and the Interior Northwest

This portfolio ties together concepts from the disciplines of ethnobotany, botany, and Traditional Ecological Knowledge (TEK). It draws on themes of native plant preservation and restoration as well as ethics of plant collection and public education regarding the native flora of Montana and the broader Interior Northwest. It is my intention to explore the many ways humans connect with plants and how they may inform our sense of place, and to provide education about the benefits of native plants so people may feel more inclined to protect them and live in right relationship with the natural environment. Overall, this portfolio aims to illustrate how learning about plants can foster a broader understanding of ecology, culture, history, and place.https://scholarworks.umt.edu/grad_portfolios/1318/thumbnail.jp

A Review of the Literature Regarding a History of Sexual Abuse as a Risk Factor for Risky Sexual Behavior in Females

Objective: This paper seeks to answer the questions: Does a history of sexual abuse predict risky sexual behavior for females? If so, by what mechanisms does this correlation occur? Method: A literature review was conducted to identify research articles that investigated the correlation between sexual abuse and sexual behavior. Cumulative Index of Nursing and Allied Health (CINAHL), Medline and PsychInfo databases were searched. Medline and CINAHL databases were searched using the terms sexual abuse and risky sexual behaviors. PsychInfo was searched using the terms sexual abuse, risky sexual behaviors, and risk taking behaviors. Studies examined multiple or single incidents of abuse and both childhood and adult victimization. Only abstracts published in English from 1997 and later were considered. Ultimately, 12 articles were reviewed and discussed. Results: There is a correlation between child and adolescent sexual abuse and risky sexual behaviors but the mechanisms by which this correlation exists are not fully understood. The mechanisms may be dependent on the interplay of pre-victimization, victimization, and post-victimization factors. Implications: This review indicates that it is important to conduct more prospective studies with various samples and sample sizes in order to clarify the mechanisms by which a victim of sexual abuse is at an increased risk for becoming involved in risky sexual behaviors

Tyrosine hydroxylase activity in the endocrine pancreas: changes induced by short-term dietary manipulation

BACKGROUND: Tyrosine hydroxylase (TH) activity and its possible participation in the control of insulin secretion were studied in pancreatic islets of adult Wistar rats fed a standard commercial diet (SD) or carbohydrates alone (CHD) for one week. TH activity, norepinephrine (NE) content, and glucose-induced insulin secretion were assessed. Blood glucose and insulin levels were measured at the time of sacrifice. RESULTS: CHD rats had significantly higher blood glucose and lower insulin levels than SD rats (114.5 ± 6.7 vs 80.7 ± 7.25 mg/dl, p < 0.001; 20.25 ± 2.45 vs 42.5 ± 4.99 μU/ml, p < 0.01, respectively). Whereas TH activity was significantly higher in CHD isolated islets (600 ± 60 vs 330 ± 40 pmol/mg protein/h; p < 0.001), NE content was significantly lower (18 ± 1 vs 31 ± 5 pmol/mg protein), suggesting that TH activity would be inhibited by the end-products of catecholamines (CAs) biosynthetic pathway. A similar TH activity was found in control and solarectomized rats (330 ± 40 vs 300 ± 80 pmol/mg protein/h), suggesting an endogenous rather than a neural origin of TH activity. CHD islets released significantly less insulin in response to glucose than SD islets (7.4 ± 0.9 vs 11.4 ± 1.1 ng/islet/h; p < 0.02). CONCLUSIONS: TH activity is present in islet cells; dietary manipulation simultaneously induces an increase in this activity together with a decrease in glucose-induced insulin secretion in rat islets. TH activity – and the consequent endogenous CAs turnover – would participate in the paracrine control of insulin secretion