EEG and EMG Sensorimotor Measurements to Assess Proprioception Following ACL Reconstruction

The Anterior Cruciate Ligament (ACL) is the primary source of rotational stability in the knee by preventing the tibia from sliding in front of the femur. When the ACL is torn, it typically must be repaired through reconstructive surgery which results in proprioceptive deficiencies in the knee. Proprioception plays an important role in understanding where one’s knee is in space, sensing movement and reacting accordingly. This study examines an alternative method of measuring proprioceptive responses to a stimulus (motion) by using electromyogram (EMG) and electroencephalogram (EEG) signals to observe muscle and brain activity. Two participants (one with an ACL reconstruction and a second with healthy knees) were tested three times over a six week period. Repeated measures allowed for an initial examination of how proprioception may vary over time in an individual with healthy knees and with an ACL reconstruction. This measurement strategy can examine the process of proprioception recovery after an ACL reconstruction. It has the potential to help physicians and physical therapists decide when a person can return to normal or strenuous activity as well as provide insight into whether uninjured patients have a proprioceptive deficit which may indicate an increased risk of injury

Jane Eyre: The Bridge Between Christianity and Folklore

Charlotte Brontё’s acclaimed novel, Jane Eyre, was first marketed as an autobiography. The story, told from the point of view of a poor orphan girl, takes on a narrative similar to that of a fairytale. In this way, a reader may find difficulty in believing this novel to be a work of nonfiction. Charlotte Brontё employs aspects of both Christianity and fantasy in her novel not to discourage her readers from believing its validity but rather to emphasize how even poor orphan girls like Jane have forces of good guiding them. Jane Eyre is fictional, yet the hardships she faces could befall anyone. Charlotte Brontё purposefully parallels her story to a fairytale to portray how even the seemingly random misfortunes and griefs of life are not without reason and that no one is helpless. With both religion and fable on her side, the orphan, Jane Eyre, was never truly alone

Preliminary evaluation of a liquid belt radiator for space applications

The liquid belt radiator (LBR) is discussed. The LBR system operates either in the sensible heat mode or in the latent heat mode. Parametric analysis shows that the LBR may reduce the mass of heat pipe radiators by 70 to 90% when the LBR surface has a total emissivity in excess of 0.3. It is indicated that the diffusion pump oils easily meet this criteria with emissivities greater than 0.8. Measurements on gallium indicate that its emissivity is probably in excess of 0.3 in the solid state when small amounts of impurities are on the surface. The point design exhibits a characteristic mass of 3.1 kg/kW of power dissipation, a mass per unit prime radiating area of approximately 0.9 kg/sq ms and a total package volume of approximately 2.50 cubic m. This compares favorably with conventional technologies which have weights on the order of 4 kg/sq m

Liquid belt radiator design study

The Liquid Belt Radiator (LBR) is an advanced concept developed to meet the needs of anticipated future space missions. A previous study documented the advantages of this concept as a lightweight, easily deployable alternative to present day space heat rejection systems. The technical efforts associated with this study concentrate on refining the concept of the LBR as well as examining the issues of belt dynamics and potential application of the LBR to intermediate and high temperature heat rejection applications. A low temperature point design developed in previous work is updated assuming the use of diffusion pump oil, Santovac-6, as the heat transfer media. Additional analytical and design effort is directed toward determining the impact of interface heat exchanger, fluid bath sealing, and belt drive mechanism designs on system performance and mass. The updated design supports the earlier result by indicating a significant reduction in system specific system mass as compared to heat pipe or pumped fluid radiator concepts currently under consideration (1.3 kg/sq m versus 5 kg/sq m)

Digital Humanities in the Classroom and Beyond: 1) How Scaffolding Saved the Day -- Integrating Omeka into Classroom Curricula 2) New Ecologies of Collaboration -- Digital Humanities and Renaissance Drama

This session will feature perspectives on digital humanities from presenters at two different institutions: 1) How Scaffolding Saved the Day: Integrating Omeka into Classroom Curricula This presentation chronicles a university’s journey to bring digital exhibiting into classrooms across the curriculum. What began as an idea for a different kind of class project became an opportunity that invites students to embrace humanities in a new light and present it on a world stage. While the experience of curating digital exhibits using Omeka transformed the student learning process, it brought numerous challenges to library staff. To overcome these challenges, the presenters embraced flipped-classroom methods and developed a scaffolded approach to providing instruction throughout the semester. Presenters will offer suggestions for developing scalable and sustainable digital humanities projects that engage students and faculty in digital literacy and demonstrate the value of new and different, outward-facing alternative research projects. 2) New Ecologies of Collaboration: Digital Humanities and Renaissance Drama This presentation on the current state of DH + Renaissance Drama Studies will address the way that DH is changing the field by raising the profile of collaborative research methods and projects, and will explore emerging models for collaboration between scholars and librarians

The Business Case for Community Paramedicine: Lessons from Commonwealth Care Alliance's Pilot Program

Mobile integrated health care and community paramedicine (MIH-CP) programs expand the role of traditional emergency medical services personnel to address non-emergency needs and bring outpatient primary and urgent care into patients' homes. These programs offer potential for reducing health care costs, eliminating unecessary emergency department use, and shifting service back to community-based and home settings. Between 2014 and 2015, the Massachusetts-based Commonwealth Care Alliance (CCA) piloted a community paramedicine prgoram, Acute Community Care (ACC), to serve its members in the Greater Boston area.This brief summarizes ACC's business case assessment, which showed that increasing patient volume after the pilot period would reuslt in net savings given the progam's success in averting unnecessary emergency care. By illustrating cost considerations for an expansion of MIH-CP services, this brief may inform the design and sustainability planning of other MIH-CP programs. The business case assessment was conducted by Mathematica Policy Research through support from the Center for Health Care Strategies' Complex Care Innovation Lab, a Kaiser Permanente Community Benefit-funded initiative

Transcriptional down-regulation of ccr5 in a subset of HIV+ controllers and their family members.

HIV +Elite and Viremic controllers (EC/VCs) are able to control virus infection, perhaps because of host genetic determinants. We identified 16% (21 of 131) EC/VCs with CD4 +T cells with resistance specific to R5-tropic HIV, reversed after introduction of ccr5. R5 resistance was not observed in macrophages and depended upon the method of T cell activation. CD4 +T cells of these EC/VCs had lower ccr2 and ccr5 RNA levels, reduced CCR2 and CCR5 cell-surface expression, and decreased levels of secreted chemokines. T cells had no changes in chemokine receptor mRNA half-life but instead had lower levels of active transcription of ccr2 and ccr5, despite having more accessible chromatin by ATAC-seq. Other nearby genes were also down-regulated, over a region of ~500 kb on chromosome 3p21. This same R5 resistance phenotype was observed in family members of an index VC, also associated with ccr2/ccr5 down-regulation, suggesting that the phenotype is heritable