The development of the South End House program for the aged

Thesis (M.S.)--Boston Universit

The development of the South End House program for the aged

Thesis (M.S.)--Boston Universit

Normal Modes of the Structural Connectome

Division of the human cortex into distinct regions is of high importance to neuroscientific inquiry. Fully-automated, multi-modal schemes of achieving such parcellation on an individual subject basis are particularly advantageous, however difficulties in inter-modal and inter-subject registration of brain images, as well as obstacles in preserving group-level correspondence of individual parcellation maps have slowed progress in this area. In parallel, there exists a relative dearth of data-driven parcellation schemes that incorporate high resolution structural connectivity metrics; the majority of widely-accepted parcellation maps in the literature have primarily used functional connectivity. Here, a fully data-driven, automated routine based on structural geometry and connectivity which achieves subject-specific cortical parcellation maps while maintaining group-level correspondence of maps is presented and optimized. Using high resolution white matter surface meshes and advanced fiber tracking techniques, a novel vertex-wise structural connectivity graph is constructed for each of 10 unrelated subjects, and the first k eigenvectors of the Laplacian Matrix of the graph's adjacency matrix are calculated. These eigenvectors represent the steady-state modes of vibration of the manifold described by this graph, and thus provide subject-specific maps of modes of connectivity in white matter. In order to obtain parcellations at varying levels of coarseness of the cortex from these eigenvectors, hierarchical agglomerative clustering is then performed on the surface mesh, where each vertex's feature vector is its profile in spectral space. Further, a multi-layer graph of all subjects is constructed, and individual parcellations with group level correspondence are obtained by agglomerative clustering of the eigenvectors of the laplacian matrix of the multi-layer graph.Bachelor of Scienc

Panel II Discussion: The Anatomy of 1983 Litigation: Best Practices in Successful Civil Rights Litigation

The Civil Rights Act of 1871 is a federal statute, numbered 42 U.S.C. § 1983, that allows people to sue the government for civil rights violations. It applies when someone acting “under color of” state-level or local law has deprived a person of rights created by the U.S. Constitution or federal statutes. It is often the basis for relief when someone has been the victim of excessive use of force or other police misconduct, ostensibly while under the authority generally vested by the state or municipality. The Qualified Immunity defense in 42 U.S.C. § 1983 claims often make them difficult to succeed, in that an element is that the rights were so clearly established that a reasonable officer would have known their conduct was a violation.33 This session of the symposium addressed the following elements of 42 U.S.C. § 1983 litigation: • The Beginning: Client and Forum Assessment, Drafting of the Complaint, identifying available resources, determining whether to join co-counsel and Media • Next Steps: Motions to Dismiss and Understanding Immunities and Pleading Requirements, Discovery (including custom, pattern, policy, and practice, and moving force) and Motions for Summary Judgment • Deciding a Trial Strategy • Jury Selection and Voir Dire (including how to handle jury selection in courts that do not permit voir dire or that permit extremely limited voir dire) • The Trial • Holding onto your Verdic