Effect of Different Powers of Er,Cr:YSGG Laser Treatment on Surface Morphology of Microhybride Composite Resin: Scanning Electron Microscope (SEM) Evaluation

Introduction: The aim of this study was to evaluate and compare microhybride composite treated by bur and different power of Erbium, Chromium doped Yttrium Scandium Gallium Garnet (Er,Cr:YSGG) laser by Scanning Electron Microscope (SEM).Methods: 21 microhybride composite blocks (DiaFil TM, DiaDent, Korea) with 2 × 4 × 4 mm dimensions were made. The bonding surface of these blocks were polished, The samples were put into 6 groups for laser irradiation as follows: Group 1 (power: 1W, Energy: 50 mJ); Group 2(power: 2 W, Energy: 100mJ); Group 3 (power: 3W, Energy: 150mJ); Group 4 (power: 4W, Energy: 200mJ); Group 5 (power: 5W, Energy: 250mJ) and Group 6(power:6 W, Energy :300mJ). One group prepared by bur- treated. All samples were prepared by repetition rate of 20 Hz. Then, the samples were prepared for SEM examination.Result: Some irregularities were seen in Er,Cr:YSGG laser samples in comparison to Bur group that produced favorable surface for adhesion of repair composite.Conclusion: Among different lasers, Er;Cr:YSGG laser can be chosen as a suitable technique for surface treatment of unsatisfactory composites.Key words: SEM evalution; laser; composite resi

Assessment of Effectiveness and Adverse Effect of New Combination Chemotherapy (irinotecan, cisplatin, and dexamethasone) in Relapse and Refractory Hodgkin Lymphoma

Background: Chemotherapy with adriamycin, bleomycin, vinblastine, and dacarbazine (ABVD regimen) cannot cure all patients with Hodgkin lymphoma. In this study, we evaluated the efficacy and adverse effect of a new regimen consist irinotecan, cisplatin, and dexamethasone (ICD) in relapsed and refractory Hodgkin lymphoma as the second to fifth line of treatment. Materials and Methods: We performed a retrospective study in 26 relapsed or refractory patients with Hodgkin lymphoma receiving at least the first-line chemotherapy regimen (ABVD) and (ICD) as salvage therapy in Thaleghany Hospital from 2012 to 2018. This regimen consisted of irinotecan 65mg/m2 D1, D8, cisplatin 30mg/m2 D1, D8, and dexamethasone 40mg D1, 2, 8, and 9 was administered every 3 weeks for 6 cycles.  Treatment was discontinued in cases of disease progression or severe toxicity. Response to treatment was evaluated after two cycles. Patients with complete and partial remission were candidate high dose chemotherapy and autologous stem cell transplantation. Twenty-four patients were enrolled in the study. The mean age of 22 patients was 31.5 (19-67) years. Seven patients (29.1%) were in the first recurrence, and 17 (70.8%) were in the second or subsequent recurrence. Results: According to this study, three patients (12.5%) had complete response, 13 (45%) had partial response, four (16.6%) had stable disease, and four (16.6%) had progressive disease. Nine patients (37.5%) received high-dose chemotherapy and autologous stem cell support after ICD regimen. None of the cycles of chemotherapy were delayed due to treatment-related adverse event. Overall survival after six months in all patients was 91%, and mortality rate was 8.3% at the end of the study. Conclusion: The goal of salvage chemotherapy in relapsed or refractory Hodgkin Lymphoma is achieving CR or PR preparation patients for stabilization with BMT. Thus, we recommend ICD as one of the most effective protocols with overall response rate of 66% in this population.  

Detection of fake opinions using time series

Today's e-commerce is highly depended on increasingly growing online customers' reviews posted in opinion sharing websites. This fact, unfortunately, has tempted spammers to target opinion sharing websites in order to promote and demote products. To date, different types of opinion spam detection methods have been proposed in order to provide reliable resources for customers, manufacturers and researchers. However, supervised approaches suffer from imbalance data due to scarcity of spam reviews in datasets, rating deviation based filtering systems are easily cheated by smart spammers, and content based methods are very expensive and majority of them have not been tested on real data hitherto. The aim of this paper is to propose a robust review spam detection system wherein the rating deviation, content based factors and activeness of reviewers are employed efficiently. To overcome the aforementioned drawbacks, all these factors are synthetically investigated in suspicious time intervals captured from time series of reviews by a pattern recognition technique. The proposed method could be a great asset in online spam filtering systems and could be used in data mining and knowledge discovery tasks as a standalone system to purify product review datasets. These systems can reap benefit from our method in terms of time efficiency and high accuracy. Empirical analyses on real dataset show that the proposed approach is able to successfully detect spam reviews. Comparison with two of the current common methods, indicates that our method is able to achieve higher detection accuracy (F-Score: 0.86) while removing the need for having specific fields of Meta data and reducing heavy computation required for investigation purposes

Chemical Composition and Antibacterial Activity of Wild Rose (Rosa canina L.) Gall Extracts against Gram-Negative Pathogenic Bacteria

Background & Objectives: Treating infections due to antibiotic-resistant bacteria is a challenge and researchers are looking for new antimicrobial compounds. Galls are abnormal plant growths caused by biological agents and have active compounds. The present study was designed to examine the antibacterial effects of different extracts of wild rose gall (Rosa canina L.) against some pathogenic Gram-negative bacilli. Materials & Methods: Methanol, acetone, and aqueous extracts from galls were prepared using Soxhlet apparatus. The antibacterial activity of the extracts was determined by agar well diffusion method, and the minimum inhibitory concentration and the minimum bactericidal concentration were assessed by  the microdilution method. The phytochemical composition of galls was investigated by Gas Chromatography-Mass Spectrometry (GC-MS) method. Results: The inhibition zones of 500 mg/ml methanol extract of wild rose gall against Escherichia coli, Pseudomonas aeruginosa, Enterobacter aerogenes, Klebsiella pneumoniae, Acinetobacter bummani, Shigella sonei, and Salmonella typhi were 26.7, 25.0, 25.7, 25.7, 26.7, 23.7 and 18.3, respectively. The antimicrobial activity of the extracts was directly related to their concentration. The extracts were active against all the pathogenic bacteria with average MICs ranging from 15.6 to 31.3 mg/ml.  The methanol extract of wild rose gall showed the highest bactericidal effect on P. aeruginosa and A. bummani at 62.5 mg/ml, respectively. Moreover, oleic acid, palmitic acid, and octadecenoic acid were composed 36.66%, 14.40%, and 13.21% of total active compounds in wild rose gall. Conclusion: All of the wild rose gall extracts showed significant antibacterial activities against Gram-negative bacilli. The antibacterial effects may be related to the high amounts of organic acids in wild rose gall extract

Incorporating author's activeness in online discussion in thread retrieval model

Online forum is one of user-generated contents available on the Internet that provides platform for knowledge sharing. However, not all messages posted can be considered of high quality and as it increases in its availability, finding quality information becomes more important and challenging. Thread retrieval model is very important in helping users to find relevance information pertaining to their topic search. As quality of post messages depends upon the author, this study aims to look at how ranking threads based on author's activeness in a forum could improve thread retrieval task compared to non-quality based ranked list. Voting models were used to convert message level quality features into thread level features and learning to rank method to combine nine features of activeness dimension for thread scoring. Different combinations of nine features under the activeness dimension with different ranking strategies are studied and its performances also compared using normalized discounted cumulative gain (NDCG) as performance measure. 2555 models were generated and 23 models are identified as among the best mode

Detection of review spam: A survey

In recent years, online reviews have become the most important resource of customers' opinions. These reviews are used increasingly by individuals and organizations to make purchase and business decisions. Unfortunately, driven by the desire for profit or publicity, fraudsters have produced deceptive (spam) reviews. The fraudsters' activities mislead potential customers and organizations reshaping their businesses and prevent opinion-mining techniques from reaching accurate conclusions. The present research focuses on systematically analyzing and categorizing models that detect review spam. Next, the study proceeds to assess them in terms of accuracy and results. We find that studies can be categorized into three groups that focus on methods to detect spam reviews, individual spammers and group spam. Different detection techniques have different strengths and weaknesses and thus favor different detection contexts

The correlation among residual nitrites, biogenic amines, N‐nitrosamine formation, and degradation occurrence of punicalagin α/β, rosmarinic acid, carnosol, and carnosic acid in extract‐treated sausage during storage

Abstract The aim of this study was to investigate the relation between residual α‐ and β‐punicalagin in Punica granatum L.; PPE and rosmarinic acid, carnosol, and carnosic acid in Salvia eremophila (SE) with residual nitrites, biogenic amines (cadaverine, putrescine, and histamine), N‐nitrosodimethylamine (NDMA), microbial counts, lipid oxidation indices, and color values in extract‐treated sausage over 14 days of storage. Sausage containing SE + nitrite 60 ppm (SSN) showed minimum levels of the residual nitrites (13.14 mg/kg), NDMA (0.74 ± 0.05 μg/kg), and biogenic amine (histamine, 1.8 mg/kg; cadaverine, 3.7 mg/kg; and putrescine, 4.3 mg/kg) due to retarded degradation rate of 285.84–216.44 mg/kg; rosmarinic acid, 41.62–33.16 mg/kg; carnosol, and 88.70–76.73 mg/kg; carnosic acid over storage time. The first‐order kinetic model fitted well for the degradation of rosmarinic acid and carnosol acid in SSN sample. TBA value remained below the threshold limit (0.32 mg kg−1) through 14 days for SSN. Second‐order and zero‐order reaction models had the best agreement with sausages' PV and TBA values, respectively. After 2 weeks of storage, E. coli and Cl. perfringens counts in the SN120 (sausage containing 120 ppm nitrite) and SSN were significantly lower than the other samples (p < .05), with the values 2.1 and 1.5 log cfu/g for SN120 and 2.2 and 1.6 log cfu/g for SSN formulation. Conversely, oxidation indices, residual nitrites, NDMA, and biogenic amine increased in sausage samples containing PPE extracts (SPN) owing to total degradation of α‐ and β‐punicalagin during storage. The results indicated that SE can be used as potential co‐preservative by reducing the levels of required nitrite in food industry