Is there a relation between changes in osmolarity of cherry fruit flesh or skin and fruit cracking susceptibility ?

International audienc

A human skin culture system for a wound-healing model.

International audienceThis study was done as the first move to the aforementioned research on the impact of tissue adhesives on scar creation. Tissue adhesives could be applied in various areas and knowledge of their mechanical properties could help in their broader usage

Development and characterization of a human dermal equivalent with physiological mechanical properties.

International audienceBACKGROUND/AIMS: Different models of reconstructed skin are available, either to provide skin wound healing when this process is deficient, or to be used as an in vitro model. Nevertheless, few studies have focused on the mechanical properties of skin equivalent. Indeed, human skin is naturally under tension. Taking into account these features, the purpose of this work was to obtain a cellularized dermal equivalent (CDE), composed of collagen and dermal fibroblasts. METHODS: To counteract the natural retraction of CDE and to maintain it under tension, different biomaterials were tested. Selection criteria were biocompatibility, bioadhesion properties, ability to induce differentiation of fibroblasts into myofibroblasts and mechanical characterization, considering that of skin in vivo. These assays led to the selection of honeycomb of polyester. CDE constructed on this biomaterial was further characterized mechanically using tensile tests. RESULTS: The results showed that mechanical features of the obtained dermal equivalent, including myofibroblasts, were similar to skin in vivo. CONCLUSION: The original model of dermal equivalent presented herein may be a useful tool for clinical use and as an in vitro model for toxicological/pharmacological research

Fine mapping and cloning of genes controlling peach fruit quality traits. A starting project (poster)

International audienc

Fine mapping and cloning of genes controlling peach fruit quality traits. A starting project (poster)

International audienc