50 research outputs found

    Alien Registration- Tarpinian, Derrick (Portland, Cumberland County)

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    https://digitalmaine.com/alien_docs/32053/thumbnail.jp

    Cost reduction methodology and management

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    Thesis (S.M.)--Massachusetts Institute of Technology, Sloan School of Management; and, (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering, 1999.by Gary Tarpinian.S.M

    Deep Underground Science and Engineering Laboratory - Preliminary Design Report

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    The DUSEL Project has produced the Preliminary Design of the Deep Underground Science and Engineering Laboratory (DUSEL) at the rehabilitated former Homestake mine in South Dakota. The Facility design calls for, on the surface, two new buildings - one a visitor and education center, the other an experiment assembly hall - and multiple repurposed existing buildings. To support underground research activities, the design includes two laboratory modules and additional spaces at a level 4,850 feet underground for physics, biology, engineering, and Earth science experiments. On the same level, the design includes a Department of Energy-shepherded Large Cavity supporting the Long Baseline Neutrino Experiment. At the 7,400-feet level, the design incorporates one laboratory module and additional spaces for physics and Earth science efforts. With input from some 25 science and engineering collaborations, the Project has designed critical experimental space and infrastructure needs, including space for a suite of multidisciplinary experiments in a laboratory whose projected life span is at least 30 years. From these experiments, a critical suite of experiments is outlined, whose construction will be funded along with the facility. The Facility design permits expansion and evolution, as may be driven by future science requirements, and enables participation by other agencies. The design leverages South Dakota's substantial investment in facility infrastructure, risk retirement, and operation of its Sanford Laboratory at Homestake. The Project is planning education and outreach programs, and has initiated efforts to establish regional partnerships with underserved populations - regional American Indian and rural populations

    Changes in breast density and circulating estrogens in postmenopausal women receiving adjuvant anastrozole

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    Factors associated with an increased risk of breast cancer include prior breast cancer, high circulating estrogens, and increased breast density. Adjuvant aromatase inhibitors are associated with a reduction in incidence of contralateral breast cancer. We conducted a prospective, single-arm, single-institution study to determine whether use of anastrozole is associated with changes in contralateral breast density and circulating estrogens. Eligible patients included postmenopausal women with hormone receptor-positive early-stage breast cancer who had completed local therapy, had an intact contralateral breast, and were recommended an aromatase inhibitor as their only systemic therapy. Participants received anastrozole 1 mg daily for 12 months on study. We assessed contralateral breast density and serum estrogens at baseline, 6, and 12 months. The primary endpoint was change in contralateral percent breast density from baseline to 12 months. Secondary endpoints included change in serum estrone sulfate from baseline to 12 months. Fifty-four patients were accrued. At 12 months, compared with baseline, there was a nonstatistically significant reduction in breast density (mean change: -16%, 95% CI: -30 to 2, P = 0.08) and a significant reduction in estrone sulfate (mean change: -93%, 95% CI: -94 to -91, P < 0.001). Eighteen women achieved 20% or greater relative reduction in contralateral percent density at 12 months compared with baseline; however, no measured patient or disease characteristics distinguished these women from the overall population. Large trials are required to provide additional data on the relationship between aromatase inhibitors and breast density and, more importantly, whether observed changes in breast density correlate with meaningful disease-specific outcomes

    Alien Registration- Tarpinian, Derrick (Portland, Cumberland County)

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    https://digitalmaine.com/alien_docs/32053/thumbnail.jp

    Effect of Molten Sodium on Thermal Insulation Specimens

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    Every type of thermal insulating material tested showed attack in varying degeces. Many specimens which had been cured at 1000 deg F, with no color change, did show drastic changes at 950 deg F due to the action of sodium. The materials showing the least disintegration and greatest preservation of mechanical properties were Superex paste and Eagle-Picher mineral wool. The uncured Superex Block did not hold up as well as Superax paste, presumably due to the presence of water of crystallization; after curing, the results were similar to that of the paste. The refractory clays showed the greatest degree of destruction. The time element is of vital importance, since a long perfod of contact with liquid sodium would presumably result in complete destruction of every specimen tested. (auth

    Prioritizing Proposed Wilderness Areas for Wilderness Designation

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    The National Wilderness Preservation System protects especially pristine public lands that have been designated by Congress as wilderness. But wilderness areas are designated without consideration of existing protected areas or conservation needs. This study uses a Geographic Information System to rank the ecological urgency of proposed wilderness areas (n=631) so that future wilderness designations can be better informed by science. Results indicate that most proposed wilderness areas are in ecosystems that are already well-protected. But a few proposals would add substantial area to currently underrepresented ecosystems. The highest-ranking proposals are Beaver Creek Wilderness Study Area (a Bureau of Land Management unit in Colorado) and Assateague Island National Seashore Recommended Wilderness (a National Park Service unit in Maryland) because they are each located in virtually unprotected regions of the United States. The data acquisition process for this study uncovered management problems within the federal agencies such as a fear of the public and overall lack of interagency collaboration. A review of the lessons learned highlights ways to improve systematic conservation planning at the federal level. Data standardization within and between agencies is a necessary step toward improved communication. Furthermore, federal land management agencies need to increase the quality and quantity of publicly available data regarding protected areas. Decision-making in the federal agencies has been extremely localized, but a new initiative in the Department of Interior seeks to change that by implementing broad-scale and science-based Landscape Conservation Cooperatives (LCCs). The new LCCs may be the appropriate arena for employing the systematic wilderness stewardship principles outlined here

    Triathlon swimming for 2000 and beyond

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    Tarpinian Steve. Triathlon swimming for 2000 and beyond. In: Les Cahiers de l'INSEP, n°24, 1999. 2e Congrès international de triathlon de l’INSEP – 2nd INSEP international triathlon Congress pp. 142-143

    Nager pour Sydney et au-delĂ 

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    Tarpinian Steve. Nager pour Sydney et au-delà. In: Les Cahiers de l'INSEP, n°24, 1999. 2e Congrès international de triathlon de l’INSEP – 2nd INSEP international triathlon Congress pp. 140-141
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