Concomitant Ulecranon Fracture, Ipsilateral Segmental Humerus Fracture and Intercondylar Humerus Fracture in a 4-Year-Old Girl: an Extremely Rare Case Report and Literature Review

T-condylar fracture of distal humerus in young children is very rare. Pure physeal fractures of the olecranon are also rare. We report on an extremely rare case of concomitant ulecranon fracture, ipsilateral segmental humerus and intercondylar humerus fracture (type III) in a skeletally immature patient

K 4-free subgraphs of random graphs revisited

In Combinatorica 17(2), 1997, Kohayakawa, Łuczak and Rödl state a conjecture which has several implications for random graphs. If the conjecture is true, then, for example, an application of a version of Szemerédi's regularity lemma for sparse graphs yields an estimation of the maximal number of edges in an H-free subgraph of a random graph G n, p . In fact, the conjecture may be seen as a probabilistic embedding lemma for partitions guaranteed by a version of Szemerédi's regularity lemma for sparse graphs. In this paper we verify the conjecture for H = K 4, thereby providing a conceptually simple proof for the main result in the paper cited abov

Repeated Assessments of Informed Consent Comprehension among HIV-Infected Participants of a Three-Year Clinical Trial in Botswana

Informed consent (IC) has been an international standard for decades for the ethical conduct of clinical trials. Yet frequently study participants have incomplete understanding of key issues, a problem exacerbated by language barriers or lack of familiarity with research concepts. Few investigators measure participant comprehension of IC, while even fewer conduct interim assessments once a trial is underway.We assessed comprehension of IC using a 20-question true/false quiz administered in 6-month intervals in the context of a placebo-controlled, randomized trial for the prevention of tuberculosis among HIV-infected adults in Botswana (2004-2009). Quizzes were offered in both Setswana and English. To enroll in the TB trial, participants were required to have ≥ 16/20 correct responses. We examined concepts understood and the degree to which understanding changed over three-years. We analyzed 5,555 quizzes from 1,835 participants. The participants' highest education levels were: 28% primary, 59% secondary, 9% tertiary and 7% no formal education. Eighty percent of participants passed the enrollment quiz (Quiz1) on their first attempt and the remainder passed on their second attempt. Those having higher than primary education and those who took the quiz in English were more likely to receive a passing score on their first attempt (adjusted odds ratios and 95% confidence intervals, 3.1 (2.4-4.0) and 1.5 (1.2, 1.9), respectively). The trial's purpose or procedures were understood by 90-100% of participants, while 44-77% understood randomization, placebos, or risks. Participants who failed Quiz1 on their initial attempt were more likely to fail quizzes later in the trial. Pass rates improved with quiz re-administration in subsequent years.Administration of a comprehension quiz at enrollment and during follow-up was feasible in a large, international collaboration and efficiently determined IC comprehension by trial participants. Strategies to improve understanding of concepts like placebos and randomization are needed. Comprehension assessments throughout a study may reinforce key concepts

Treatment of dorsal fracture-dislocations of the proximal interphalangeal joint using the shotgun approach

This study assessed the outcome of open reduction and internal fixation of proximal interphalangeal joint fracture-dislocations through a shotgun approach, while keeping hemi-hamate arthroplasty as a back-up plan. After using the shotgun approach, fixation was carried out when the anterior fragment was large enough to accept two 1.5 mm screws. Sixty-three fracture-dislocations were treated in 61 patients, of whom 30 underwent internal fixation. Twenty-one of these were assessed in the final study. At a mean follow-up of 29 months, the mean range of joint motion was 80° and 102° for the injured and contralateral hand, respectively. The mean pinch and grip strengths of injured hand were 82 and 83 of contralateral hand, respectively. The mean disabilities of the arm, shoulder and hand score was 5.5. The mean visual analogue pain score was 1.6. Surgery through the versatile shotgun approach allows excellent intra-operative assessment and acceptable outcomes. Level of evidence: IV. © 2018, © The Author(s) 2018