6 research outputs found
Improving the effectiveness of point of care tests for malaria and anaemia: a qualitative study across three Ghanaian antenatal clinics
Background: Anaemia and malaria are both major contributors to maternal and child mortality, and morbidity,
with some of the worst outcomes occurring in sub-Saharan Africa. Point of care tests (POCT), if used appropriately,
provide a simple, inexpensive form of diagnostic testing, as a reliable alternative when laboratory tests are not
readily available. In such resource limited settings, clinical staff tend to rely on symptom-based diagnosis and
presumptive treatment. This study uses qualitative methods to identify the current practice of POCT use for malaria
and anaemia, to explore the enablers and barriers to effective implementation of these POCT, and to determine
how relationships between each of the stakeholder groups may impact on POCT use.
Methods: Staff (clinical and laboratory) and patients (pregnant women) at three antenatal care facilities within the
Ashanti Region of Ghana participated in interviews and focus group discussions (FGDs). An initial coding framework
was developed based on the pre-defined objectives of the study. Thematic analysis was used to identify subthemes
and categories within each of the key themes.
Results: At the time data were collected all three facilities used malaria POCT either as an adjunct to microscopy, or
as their only form of malaria testing. Although all three facilities were familiar with haemoglobin colour scale (HCS),
none of the facilities used them routinely. Clinical staff perceived symptom-based diagnosis was a quick way to
diagnosis because access to POCT during consultations was unreliable, but recognized disadvantages associated
with symptom-based diagnosis.
Perceived advantages of malaria and anaemia POCT were user-friendliness, improved diagnosis and opportunity for
patient engagement, as well as lower cost implication for patients. Perceived disadvantages included likelihood of
missed diagnosis of mild anaemia, as well as likelihood of human error leading to in accurate diagnosis which
could impact on patient trust. Poor communication and lack of trust between staff groups was also identified as a
barrier to effective uptake of POCT.
Conclusions: Consistent supply of POCT as well as staff training and staff and patient engagement, are
fundamental to successful uptake of POCT for effective malaria and anaemia management.
Keywords: Antenatal care, Malaria and anaemia in pregnancy, Active participation, Rapid diagnostic test,
Haemoglobin colour scale, LMIC, Ghan
Developing research tools to assess laboratory systems’ capacities for the control of neglected tropical diseases
The lack of capacity in laboratory systems is a barrier in the control of neglected tropical diseases (NTDs).
•Capacity strengthening traditionally focuses on individuals’ skills or institutional quality ignoring wider national/international structures, which are integral to establishing sustainable capacity.
•Published methodologies of how to assess capacity in laboratory systems are scarce.
•As researchers within the Capacity Strengthening Implementation Research (CSIR) unit we use operational research techniques to generate high quality robust evidence to aid the design and evaluation of capacity strengthening initiatives
Comparison of existing strengths in laboratories included in our project.
<p>Comparison of existing strengths in laboratories included in our project.</p
Description of laboratories included in our project.
<p>Description of laboratories included in our project.</p
A Systematic Approach to Capacity Strengthening of Laboratory Systems for Control of Neglected Tropical Diseases in Ghana, Kenya, Malawi and Sri Lanka
Background
The lack of capacity in laboratory systems is a major barrier to achieving the aims of the London Declaration (2012) on neglected tropical diseases (NTDs). To counter this, capacity strengthening initiatives have been carried out in NTD laboratories worldwide. Many of these initiatives focus on individuals' skills or institutional processes and structures ignoring the crucial interactions between the laboratory and the wider national and international context. Furthermore, rigorous methods to assess these initiatives once they have been implemented are scarce. To address these gaps we developed a set of assessment and monitoring tools that can be used to determine the capacities required and achieved by laboratory systems at the individual, organizational, and national/international levels to support the control of NTDs.
Methodology and principal findings
We developed a set of qualitative and quantitative assessment and monitoring tools based on published evidence on optimal laboratory capacity. We implemented the tools with laboratory managers in Ghana, Malawi, Kenya, and Sri Lanka. Using the tools enabled us to identify strengths and gaps in the laboratory systems from the following perspectives: laboratory quality benchmarked against ISO 15189 standards, the potential for the laboratories to provide support to national and regional NTD control programmes, and the laboratory's position within relevant national and international networks and collaborations.
Conclusion
We have developed a set of mixed methods assessment and monitoring tools based on evidence derived from the components needed to strengthen the capacity of laboratory systems to control NTDs. Our tools help to systematically assess and monitor individual, organizational, and wider system level capacity of laboratory systems for NTD control and can be applied in different country contexts