Unsupervised Low Light Image Enhancement Using SNR-Aware Swin Transformer

Image captured under low-light conditions presents unpleasing artifacts, which debilitate the performance of feature extraction for many upstream visual tasks. Low-light image enhancement aims at improving brightness and contrast, and further reducing noise that corrupts the visual quality. Recently, many image restoration methods based on Swin Transformer have been proposed and achieve impressive performance. However, On one hand, trivially employing Swin Transformer for low-light image enhancement would expose some artifacts, including over-exposure, brightness imbalance and noise corruption, etc. On the other hand, it is impractical to capture image pairs of low-light images and corresponding ground-truth, i.e. well-exposed image in same visual scene. In this paper, we propose a dual-branch network based on Swin Transformer, guided by a signal-to-noise ratio prior map which provides the spatial-varying information for low-light image enhancement. Moreover, we leverage unsupervised learning to construct the optimization objective based on Retinex model, to guide the training of proposed network. Experimental results demonstrate that the proposed model is competitive with the baseline models

Transplantation of Porcine Hepatocytes Cultured with Polylactic Acid-O-Carboxymethylated Chitosan Nanoparticles Promotes Liver Regeneration in Acute Liver Failure Rats

In this study, free porcine hepatocytes suspension (Group A), porcine hepatocytes embedded in collagen gel (Group B), porcine hepatocytes cultured with PLA-O-CMC nanoparticles and embedded in collagen gel (Group C), and PLA-O-CMC nanoparticles alone (Group D) were transplanted into peritoneal cavity of ALF rats, respectively. The result showed that plasma HGF levels were elevated post-transplantation with a peak at 12 hr. The rats in Group C showed highest plasma HGF levels at 2, 6, 12, 24 and 36 hr post-transplantation and lowest HGF level at 48 hr. Plasma VEGF levels were elevated at 48 hr post-transplantation with a peak at 72 hr. The rats in Group C showed highest plasma HGF levels at 48, 72, and 96 hr post-transplantation. The liver functions in Group C were recovered most rapidly. Compared with Group B, Group C had significant high liver Kiel 67 antigen labeling index (Ki-67 LI) at day 1 post-HTx (P < .05). Ki-67 LI in groups B and C was higher than that in groups A and D at days 5 and 7 post-HTx. In conclusion, intraperitoneal transplantation of porcine hepatocytes cultured with PLA-O-CMC nanoparticles and embedded in collagen gel can promote significantly liver regeneration in ALF rats

MQ Signature and Proxy Signature Schemes with Exact Security Based on UOV Signature

Multivariate public key cryptography which relies on MQ (Multivariate Quadratic) problems is one of the main approaches to guarantee the security of communication in the post-quantum world. In this paper, we propose a combined MQ signature scheme based on the yet unbroken UOV (Unbalanced Oil and Vinegar) signature if parameters are properly chosen. Our scheme can not only reduce the public key size of the UOV signature, but also provide more tighter bound of security against chosen-message attack in the random oracle model. On the other hand, we propose a proxy signature scheme based on our proposed combined signature scheme. Additionally, we give a strict security proof for our proxy signature scheme. Finally, we present experiments for all of our proposed schemes and the baseline schemes. Comparisons with related schemes show that our work has some advantages on performance along with more strict security

Towards Understanding Third-party Library Dependency in C/C++ Ecosystem

Third-party libraries (TPLs) are frequently reused in software to reduce development cost and the time to market. However, external library dependencies may introduce vulnerabilities into host applications. The issue of library dependency has received considerable critical attention. Many package managers, such as Maven, Pip, and NPM, are proposed to manage TPLs. Moreover, a significant amount of effort has been put into studying dependencies in language ecosystems like Java, Python, and JavaScript except C/C++. Due to the lack of a unified package manager for C/C++, existing research has only few understanding of TPL dependencies in the C/C++ ecosystem, especially at large scale. Towards understanding TPL dependencies in the C/C++ecosystem, we collect existing TPL databases, package management tools, and dependency detection tools, summarize the dependency patterns of C/C++ projects, and construct a comprehensive and precise C/C++ dependency detector. Using our detector, we extract dependencies from a large-scale database containing 24K C/C++ repositories from GitHub. Based on the extracted dependencies, we provide the results and findings of an empirical study, which aims at understanding the characteristics of the TPL dependencies. We further discuss the implications to manage dependency for C/C++ and the future research directions for software engineering researchers and developers in fields of library development, software composition analysis, and C/C++package manager.Comment: ASE 202

Sulfur-doped TiO2 anchored on a large-area carbon sheet as a high-performance anode for sodium-ion battery

Well-tailored sulfur-doped anatase titanium dioxide nanoparticles anchored on a large-area carbon sheet are designed, where the in situ sulfur-doped titanium dioxide directly comes from titanium oxysulfate and the large-area carbon sheet is derived from glucose. When applied as an anode material for sodium-ion batteries, it exhibits an excellent electrochemical performance including a high capacity [256.4 mA h g–1 at 2 C (1 C = 335 mA h g–1) after 500 cycles] and a remarkable rate of cycling stability (100.5 mA h g–1 at 30 C after 500 cycles). These outstanding sodium storage behaviors are ascribed to the nanosized particles (about 8–12 nm), good electronic conductivity promoted by the incorporation of carbon sheet and sulfur, as well as the unique chemical bond based on the electrostatic interaction

Field-of-view optimized and constrained undistorted single-shot study of intravoxel incoherent motion and diffusion-weighted imaging of the uterus during the menstrual cycle: a prospective study

PURPOSEThis study aimed to compare the variability of the uterus during the menses phase (MP), follicular phase (FP), and luteal phase (LP) of the menstrual cycle using intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI).METHODSThis prospective study was conducted at the Guangdong Provincial Hospital of Traditional Chinese Medicine between January 2022 and January 2023. Women of childbearing age (18–45 years) with appropriate progesterone levels were included in this study. Conventional magnetic resonance imaging and IVIM-DWI scans were performed during the MP, FP, and LP. The differences in IVIM-DWI-derived parameters between these phases were then compared, and the overlap was quantitatively described.RESULTSThe apparent diffusion coefficient (ADC) and pure molecular diffusion coefficient (D) values from the endometrium, uterine junctional zone (UJZ), and myometrium indicated statistical differences between the MP and FP and the MP and LP (ADC: endometrium, both P < 0.001; UJZ, P = 0.008 and P < 0.001, respectively; myometrium, P = 0.033 and P = 0.006, respectively; D: endometrium, both P < 0.001; UJZ, P = 0.008 and P = 0.006, respectively; myometrium, P = 0.041 and P = 0.045, respectively). The perfusion-related diffusion coefficient (D*) values from the myometrium indicated statistical differences between the FP and MP and the FP and LP (D*: myometrium, P = 0.049 and P = 0.009, respectively). The overlapping endometrium ratios between the MP and FP or LP were lower than 50% in the ADC and D values (ADC: overlapping of MP and FP: 33.33%, overlapping of MP and LP: 23.33%; D: overlapping of MP and FP: 40.00%, overlapping of MP and LP: 43.33%).CONCLUSIONThe ADC and IVIM-derived parameters indicated differences in the uterus in diverse phases of the menstrual cycle, especially in the endometrium in relation to ADC and D values

Overexpression of CX3CR1 in Adipose-Derived Stem Cells Promotes Cell Migration and Functional Recovery After Experimental Intracerebral Hemorrhage

Stem cell therapy has emerged as a new promising therapeutic strategy for intracerebral hemorrhage (ICH). However, the efficiency of stem cell therapy is partially limited by low retention and engraftment of the delivered cells. Therefore, it’s necessary to improve the migration ability of stem cells to the injured area in order to save the costs and duration of cell preparation. This study aimed to investigate whether overexpression of CX3CR1, the specific receptor of chemokine fractalkine (FKN), in adipose-derived stem cells (ADSCs) can stimulate the cell migration to the injured area in the brain, improve functional recovery and protect against cell death following experimental ICH. ADSCs were isolated from subcutaneous adipose tissues of rats. ICH was induced by means of an injection of collagenase type VII. ELISA showed that the expression levels of fractalkine/FKN were increased at early time points, with a peak at day 3 after ICH. And it was found that different passages of ADSCs could express the chemokine receptor CX3CR1. Besides, the chemotactic movements of ADSCs toward fractalkine have been verified by transwell migration assay. ADSCs overexpressing CX3CR1 were established through lentivirus transfection. We found that after overexpression of CX3CR1 receptor, the migration ability of ADSCs was increased both in vitro and in vivo. In addition, reduced cell death and improved sensory and motor functions were seen in the mice ICH model. Thus, ADSCs overexpression CX3CR1 might be taken as a promising therapeutic strategy for the treatment of ICH