50 research outputs found
CD44 isoforms containing exon V3 are responsible for the presentation of heparin-binding growth factor.
Perioperative echocardiography-guided hemodynamic therapy in high-risk patients:a practical expert approach of hemodynamically focused echocardiography
The number of high-risk patients undergoing surgery is growing. To maintain adequate hemodynamic functioning as well as oxygen delivery to the vital organs (DO2) amongst this patient population, a rapid assessment of cardiac functioning is essential for the anesthesiologist. Pinpointing any underlying cardiovascular pathophysiology can be decisive to guide interventions in the intraoperative setting. Various techniques are available to monitor the hemodynamic status of the patient, however due to intrinsic limitations, many of these methods may not be able to directly identify the underlying cause of cardiovascular impairment. Hemodynamic focused echocardiography, as a rapid diagnostic method, offers an excellent opportunity to examine signs of filling impairment, cardiac preload, myocardial contractility and the function of the heart valves. We thus propose a 6-step-echocardiographic approach to assess high-risk patients in order to improve and maintain perioperative DO2. The summary of all echocardiographic based findings allows a differentiated assessment of the patient's cardiovascular function and can thus help guide a (patho)physiological-orientated and individualized hemodynamic therapy
Linear optimization model of urban areas’ operating efficiency
The efficiency of urban transportation is getting more and more important because of the increasing rate of mobility demand. To plan, control and organize urban transportation in the most efficient way, we also need to consider the aspects of land use. To handle both of the mentioned urban planning areas together, we shall develop models, which are able to pay attention to all of their restrictive factors in the most simple way. It is a possible solution to simulate the urban area through a linear programming model
The linkage between climate change and energy consumption of Hungary in the road transportation sector
The aim of this article is to prove the connection between CO2 emission and climate change, and to estimate the CO2 emission of the transport sector in Hungary. We have to clarify the emission of the transport sector in order to get information on externalities, which is a further step toward a sustainable society. The sustainable development is a development, where the pace of technical development, the satiation of increasing supply and the raw materials and resources of Earth are poised so that the rate of living and opportunities of the next generations need not be worse. One of the most emphasized goals of the transport policy of the European Union is sustainable mobility. For this reason transportation systems must be developed and standardized, the effectiveness of transportation services must be increased, while the environmental pollution must be decreased or prevented. Decoupling motorization from environmental pollution is the task for engineers. Decoupling the increase of economical activity from mobility is the task for economists
Introducing decisive development orientations into transport modelling
To effectuate a consistent methodology for urban planning taking into consideration the viewpoints of land use and transportation, we need to approach the subject and consider complex social and economical aspects. To handle both of the above mentioned urban planning areas, we shall develop models able to pay attention to all of their restrictive factors within temporal properties