Leadership Challenges In Today’s Academia

Starting from the anecdotic hypothesis that “leading academics is like trying to herd cats”, the paper reviews the main challenges and barriers to present academic leadership. The context is that of the on-going Bologna transformation of the university, and of the renewed quest for competitiveness. The method employed is that of the individual case-study, with a single-embedded design. The case study is exploratory, as we don’t know from sure which the effects of leadership in the university are, and to what degree are they alike, across sub-units of study. The case study is also intrinsic, as its main outcome is not theory-building, but understanding the particularities of a phenomenon strongly tied to its context. Our unit of study is the largest business university in the country, with its faculties and departments. The main data sources are short structured interviews with members of the academic staff. The analysis implies both explanation-building and cross-case synthesis. The results of the study give insights on the context of leadership, enablers and barriers, as well as on the content of leadership, in the particular setting of the academia. Conclusions connect our research with similar endeavours, outlining the particularities and patterns of educational transition in a transition country.academic leadership, structural equation model of academic leadership, Romanian academia

Gracilis myocutaneous flap for perineal defect reconstruction after left hemivulvectomy for locally invasive vulvar cancer – A case report and a literature review

Performing radical surgery for locally advanced vulvar cancer is usually associated with the occurrence of large perineal defects. In order to provide a better healing process of the perineal wound, different reconstructive techniques have been proposed. We present the case of a 63-year-old female patient diagnosed with locally advanced vulvar cancer for which a left hemivulvectomy with bilateral inguinal lymph node dissection was performed. After completion of the resection phase, the reconstruction with gracilis myocutaneous flap was performed. The patient developed a non-union of the flap. However, it slowly healed without any surgical re-intervention. Gracilis myocutaneous flap seems to be an effective and feasible method of perineal reconstruction after extended perineal resection for gynecological malignancies, including vulvar cancer. The method appears effective even in pre-irradiated patients with larger perineal wounds resulting after total pelvic exenteration for locally advanced gynecological malignancies

Leadership Challenges In Today’s Academia

Starting from the anecdotic hypothesis that “leading academics is like trying to herd cats”, the paper reviews the main challenges and barriers to present academic leadership. The context is that of the on-going Bologna transformation of the university, and of the renewed quest for competitiveness. The method employed is that of the individual case-study, with a single-embedded design. The case study is exploratory, as we don’t know from sure which the effects of leadership in the university are, and to what degree are they alike, across sub-units of study. The case study is also intrinsic, as its main outcome is not theory-building, but understanding the particularities of a phenomenon strongly tied to its context. Our unit of study is the largest business university in the country, with its faculties and departments. The main data sources are short structured interviews with members of the academic staff. The analysis implies both explanation-building and cross-case synthesis. The results of the study give insights on the context of leadership, enablers and barriers, as well as on the content of leadership, in the particular setting of the academia. Conclusions connect our research with similar endeavours, outlining the particularities and patterns of educational transition in a transition country

Leadership Challenges In Today’s Academia

Starting from the anecdotic hypothesis that “leading academics is like trying to herd cats”, the paper reviews the main challenges and barriers to present academic leadership. The context is that of the on-going Bologna transformation of the university, and of the renewed quest for competitiveness. The method employed is that of the individual case-study, with a single-embedded design. The case study is exploratory, as we don’t know from sure which the effects of leadership in the university are, and to what degree are they alike, across sub-units of study. The case study is also intrinsic, as its main outcome is not theory-building, but understanding the particularities of a phenomenon strongly tied to its context. Our unit of study is the largest business university in the country, with its faculties and departments. The main data sources are short structured interviews with members of the academic staff. The analysis implies both explanation-building and cross-case synthesis. The results of the study give insights on the context of leadership, enablers and barriers, as well as on the content of leadership, in the particular setting of the academia. Conclusions connect our research with similar endeavours, outlining the particularities and patterns of educational transition in a transition country

Gracilis myocutaneous flap for perineal defect reconstruction after left hemivulvectomy for locally invasive vulvar cancer – A case report and a literature review

Performing radical surgery for locally advanced vulvar cancer is usually associated with the occurrence of large perineal defects. In order to provide a better healing process of the perineal wound, different reconstructive techniques have been proposed. We present the case of a 63-year-old female patient diagnosed with locally advanced vulvar cancer for which a left hemivulvectomy with bilateral inguinal lymph node dissection was performed. After completion of the resection phase, the reconstruction with gracilis myocutaneous flap was performed. The patient developed a non-union of the flap. However, it slowly healed without any surgical re-intervention. Gracilis myocutaneous flap seems to be an effective and feasible method of perineal reconstruction after extended perineal resection for gynecological malignancies, including vulvar cancer. The method appears effective even in pre-irradiated patients with larger perineal wounds resulting after total pelvic exenteration for locally advanced gynecological malignancies

Overview of the Side-Effects of FDA- and/or EMA-Approved Targeted Therapies for the Treatment of Hematological Malignancies.

To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked DownloadIn the last decade there has been tremendous effort in offering better therapeutic management strategies to patients with hematologic malignancies. These efforts have ranged from biological to clinical approaches and resulted in the rapid development of new approaches. The main "problem" that comes with the high influx of newly approved drugs, which not only influences hematologists that frequently work with these drugs but also affects other healthcare professionals that work with hematologists in patient management, including intensive care unit (ICU) physicians, is they have to keep up within their specialty and, in addition, with the side-effects that can occur when encountering hematology-specific therapies. Nonetheless, there are few people that have an in-depth understanding of a specialty outside theirs. Thus, this manuscript offers an overview of the most common side-effects caused by therapies used in hematology nowadays, or that are currently being investigated in clinical trials, with the purpose to serve as an aid to other specialties. Nevertheless, because of the high amount of information on this subject, each chapter will offer an overview of the side-effects of a drug class with each reference of the section being intended as further reading. Keywords: hematological malignancies; life-threatening side-effects; novel therapies.MDPI A

Continuous renal replacement therapy in cytokine release syndrome following immunotherapy or cellular therapies?

To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked DownloadRecently, an increasing number of novel drugs were approved in oncology and hematology. Nevertheless, pharmacology progress comes with a variety of side effects, of which cytokine release syndrome (CRS) is a potential complication of some immunotherapies that can lead to multiorgan failure if not diagnosed and treated accordingly. CRS generally occurs with therapies that lead to highly activated T cells, like chimeric antigen receptor T cells or in the case of bispecific T-cell engaging antibodies. This, in turn, leads to a proinflammatory state with subsequent organ damage. To better manage CRS there is a need for specific therapies or to repurpose strategies that are already known to be useful in similar situations. Current management strategies for CRS are represented by anticytokine directed therapies and corticosteroids. Based on its pathophysiology and the resemblance of CRS to sepsis and septic shock, as well as based on the principles of initiation of continuous renal replacement therapy (CRRT) in sepsis, we propose the rationale of using CRRT therapy as an adjunct treatment in CRS where all the other approaches have failed in controlling the clinically significant manifestations.School of Doctoral Studies - Iuliu Hatieganu University Romanian Government Ion Chiricuta Oncology Institute Cluj Napoca Iuliu Hatieganu University of Medicine and Pharmacy Cluj Napoca European Economic Spac