Single Transverse-Spin Asymmetry in Large PTP_T Open Charm Production at an Electron-Ion Collider

We discuss the single transverse-spin asymmetry (SSA) to be observed in the $D$-meson production with large transverse-momentum in semi-inclusive deep inelastic scattering, $e p^\uparrow \rightarrow e D X$. This contribution is embodied as a twist-3 mechanism in the collinear factorization, which is induced by purely gluonic correlation inside the transversely-polarized nucleon, in particular, by the three-gluon correlation effects. The complete formula for the corresponding SSA in the leading-order QCD is expressed in terms of the four independent gluonic correlation functions and reveals the five independent structures with respect to the dependence on the azimuthal angle for the produced $D$-meson. We present the numerical calculations of the SSA formula at the kinematics relevant to a future Electron Ion Collider.Comment: 16 pages, 7 figure

On the contribution of twist-3 multi-gluon correlation functions to single transverse-spin asymmetry in SIDIS

We study the single spin asymmetry (SSA) induced by purely gluonic correlation inside a nucleon, in particular, by the three-gluon correlation functions in the transversely polarized nucleon, $p^\uparrow$. This contribution is embodied as a twist-3 mechanism in the collinear factorization framework and controls the SSA to be observed in the $D$-meson production with large transverse-momentum in semi-inclusive DIS (SIDIS), $ep^\uparrow \rightarrow eDX$. We define the relevant three-gluon correlation functions in the nucleon, and determine their complete set at the twsit-3 level taking into account symmetry constraints in QCD. We derive the single-spin-dependent cross section for the $D$-meson production in SIDIS, taking into account all the relevant contributions at the twist-3 level. The result is obtained in a manifestly gauge-invariant form as the factorization formula in terms of the three-gluon correlation functions and reveals the five independent structures with respect to the dependence on the azimuthal angle for the produced $D$ meson. We also demonstrate the remarkable relation between the twist-3 single-spin-dependent cross section and twist-2 cross sections for the $D$-meson production, as a manifestation of universal structure behind the SSA in a variety of hard processes.Comment: 8 pages, 2 figures. To appear in the proceedings of the 19th International Spin Physics Symposium (SPIN2010), Juelich, Germany, Sept.27 - Oct.2, 201

Stapled intestinal anastomosis is a simple and reliable method for management of intestinal caliber discrepancy in children

PURPOSE: Popularity of minimally invasive surgeries has led to the development of stapled intestinal anastomosis for adults. The advanced instruments used in this technique are getting suitable with the small intestinal lumens of neonates and infants. We reviewed and compared the intraoperative and postoperative results of stapled and hand-sewn anastomoses in children. METHODS: The operative data of children who underwent stapled and hand-sewn anastomoses between March 2005 and December 2011 were collected and analyzed retrospectively. Furthermore, we compared patients who underwent anastomoses for colostomy closure of anorectal malformation (4 stapled, 9 hand-sewn) and those who underwent anastomoses for treatment of ileal atresia (3 stapled, 11 hand-sewn). RESULTS: In the 47 patients who underwent stapled anastomosis, no intraoperative complications were observed and postoperative complications included wound infection (n = 3), delayed gastric emptying (n = 1), and ileus (n = 1). No complications suggesting anastomotic dilatation were identified. It was observed that patients who underwent stapled anastomosis for colostomy takedown with caliber discrepancy had significantly shorter surgery time than those who underwent hand-sewn anastomosis. CONCLUSION: Our results suggest that stapled anastomosis is safe and effective for various surgical diseases in neonates, infants, and children

Contribution of Twist-3 Multi-Gluon Correlation Functions to Single Spin Asymmetry in Semi-Inclusive Deep Inelastic Scattering

As a possible source of the single transverse spin asymmetry, we study the contribution from purely gluonic correlation represented by the twist-3 ``three-gluon correlation" functions in the transversely polarized nucleon. We first define a complete set of the relevant three-gluon correlation functions, and then derive its contribution to the twist-3 single-spin-dependent cross section for the $D$-meson production in semi-inclusive deep inelastic scattering, which is relevant to determine the three-gluon correlations. Our cross-section formula differs from the corresponding result in the literature, and the origin of the discrepancy is clarified.Comment: 29 pages, 3 figures minor corrections; version to appear in Phys. Rev.

Development of integrated analysis software of observation data in the upper atmosphere

Workshop at NARL, Gadanki, India27-29 March 2011 - Recent Advances in Observational Studies of the Tropical Atmosphere and Ionosphere

Facilitation of NMDAR-Independent LTP and Spatial Learning in Mutant Mice Lacking Ryanodine Receptor Type 3

AbstractTo evaluate the role in synaptic plasticity of ryanodine receptor type 3 (RyR3), which is normally enriched in hippocampal area CA1, we generated RyR3-deficient mice. Mutant mice exhibited facilitated CA1 long-term potentiation (LTP) induced by short tetanus (100 Hz, 100 ms) stimulation. Unlike LTP in wild-type mice, this LTP was not blocked by the NMDA receptor antagonist D-AP5 but was partially dependent on L-type voltage-dependent Ca2+ channels (VDCCs) and metabotropic glutamate receptors (mGluRs). Long-term depression (LTD) was not induced in RyR3-deficient mice. RyR3-deficient mice also exhibited improved spatial learning on a Morris water maze task. These results suggest that in wild-type mice, in contrast to the excitatory role of Ca2+ influx, RyR3-mediated intracellular Ca2+ ([Ca2+]i) release from endoplasmic reticulum (ER) may inhibit hippocampal LTP and spatial learning

A formylpeptide receptor, FPRL1, acts as an efficient coreceptor for primary isolates of human immunodeficiency virus

<p>Abstract</p> <p>Background</p> <p>More than 10 members of seven-transmembrane G protein-coupled receptors (GPCRs) have been shown to work as coreceptors for human immunodeficiency virus type 1 (HIV-1), HIV type 2 (HIV-2), and simian immunodeficiency viruses (SIVs). As a common feature of HIV/SIV coreceptors, tyrosine residues are present with asparagines, aspartic acids or glutamic acids in the amino-terminal extracellular regions (NTRs).</p> <p>We noticed that a receptor for N-formylpeptides, FPRL1, also contains two tyrosine residues accompanied by glutamic acids in its NTR. It was reported that monocytes expressing CCR5 and FPRL1 in addition to CD4 are activated by treatment with ligands or agonists of FPRL1. Activated monocytes down-modulate CCR5 and become resistant to infection by HIV-1 strains. Thus, FPRL1 plays important roles in protection of monocyptes against HIV-1 infection. However, its own coreceptor activity has not been elucidated yet. In this study, we examined coreceptor activities of FPRL1 for HIV/SIV strains including primary HIV-1 isolates.</p> <p>Results</p> <p>A CD4-transduced human glioma cell line, NP-2/CD4, is strictly resistant to HIV/SIV infection. We have reported that when NP-2/CD4 cells are transduced with a GPCR having coreceptor activity, the cells become susceptible to HIV/SIV strains. When NP-2/CD4 cells were transduced with FPRL1, the resultant NP-2/CD4/FPRL1 cells became markedly susceptible to some laboratory-adapted HIV/SIV strains. We found that FPRL1 is also efficiently used as a coreceptor by primary HIV-1 isolates as well as CCR5 or CXCR4.</p> <p>Amino acid sequences linked to the FPRL1 use could not be detected in the V3 loop of the HIV-1 Env protein. Coreceptor activities of FPRL1 were partially blocked by the forymyl-Met-Leu-Phe (fMLF) peptide.</p> <p>Conclusion</p> <p>We conclude that FPRL1 is a novel and efficient coreceptor for HIV/SIV strains. FPRL1 works as a bifunctional factor in HIV-1 infection. Namely, the role of FPRL1 in HIV-1 infection is protective and/or promotive in different conditions. FPRL1 has been reported to be abundantly expressed in the lung, spleen, testis, and neutrophils. We detected mRNA expression of FPRL1 in 293T (embryonal kidney cell line), C8166 (T cell line), HOS (osteosarcoma cell line), Molt4#8 (T cell line), U251MG (astrocytoma cell line), U87/CD4 (CD4-transduced glioma cell line), and peripheral blood lymphocytes. Roles of FPRL1 in HIV-1 infection <it>in vivo </it>should be further investigated.</p

A case of chronic pancreatitis successfully treated by endoscopic removal of protein plugs.

A 56 years old male with chronic pancreatitis complained of intractable abdominal pain, anorexia, emaciation and peripheral edema. Medical treatment initiated only partial improvement in the general condition and hypoproteinemia. Endoscopic retrograde cholangiopancreatography revealed multiple filling defects in the dilated main pancreatic duct. Endoscopic aspiration of pure pancreatic juice yielded numerous protein plugs. The endoscopic removal of protein plugs from the pancreatic duct resulted in remarkable improvement in symptoms, laboratory findings and ERCP findings. We consider this procedure to be an important new treatment of chronic pancreatitis.</p

A case of chronic pancreatitis successfully treated by endoscopic removal of protein plugs.

A 56 years old male with chronic pancreatitis complained of intractable abdominal pain, anorexia, emaciation and peripheral edema. Medical treatment initiated only partial improvement in the general condition and hypoproteinemia. Endoscopic retrograde cholangiopancreatography revealed multiple filling defects in the dilated main pancreatic duct. Endoscopic aspiration of pure pancreatic juice yielded numerous protein plugs. The endoscopic removal of protein plugs from the pancreatic duct resulted in remarkable improvement in symptoms, laboratory findings and ERCP findings. We consider this procedure to be an important new treatment of chronic pancreatitis.</p