2,900 research outputs found
Performance analysis of brushless DC motors including features of the control loop in the finite element modeling
Author name used in this publication: S. L. HoAuthor name used in this publication: H. C. WongAuthor name used in this publication: W. N. Fu2001-2002 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe
Epilepsy Is a Risk Factor for Sudden Cardiac Arrest in the General Population
Background
People with epilepsy are at increased risk for sudden death. The most prevalent cause of sudden death in the general population is sudden cardiac arrest (SCA) due to ventricular fibrillation (VF). SCA may contribute to the increased incidence of sudden death in people with epilepsy. We assessed whether the risk for SCA is increased in epilepsy by determining the risk for SCA among people with active epilepsy in a community-based study.
Methods and Results
This investigation was part of the Amsterdam Resuscitation Studies (ARREST) in the Netherlands. It was designed to assess SCA risk in the general population. All SCA cases in the study area were identified and matched to controls (by age, sex, and SCA date). A diagnosis of active epilepsy was ascertained in all cases and controls. Relative risk for SCA was estimated by calculating the adjusted odds ratios using conditional logistic regression (adjustment was made for known risk factors for SCA). We identified 1019 cases of SCA with ECG-documented VF, and matched them to 2834 controls. There were 12 people with active epilepsy among cases and 12 among controls. Epilepsy was associated with a three-fold increased risk for SCA (adjusted OR 2.9 [95%CI 1.1–8.0.], p = 0.034). The risk for SCA in epilepsy was particularly increased in young and females.
Conclusion
Epilepsy in the general population seems to be associated with an increased risk for SCA
Rupture of the profunda femoris artery in a patient with alcoholic liver disease: a case report
Introduction: Profunda femoris artery aneurysms are rare and often present with rupture. However, to the best of our knowledge, rupture of a non-aneurismal profunda femoris artery has never been reported before.
Case presentation: We report the case of a 31-year-old Caucasian man with alcoholic liver disease who presented with rupture of the profunda femoris artery following blunt trauma which was treated by endovascular embolization.
Conclusion: Coagulopathy secondary to alcoholic liver disease is a major contributory factor and a high index of suspicion of vascular injury must be attached to such patients following blunt trauma. Although there have no previous documented cases, treatment by endovascular embolization appears to be effective and safe
Supergravity Higgs Inflation and Shift Symmetry in Electroweak Theory
We present a model of inflation in a supergravity framework in the Einstein
frame where the Higgs field of the next to minimal supersymmetric standard
model (NMSSM) plays the role of the inflaton. Previous attempts which assumed
non-minimal coupling to gravity failed due to a tachyonic instability of the
singlet field during inflation. A canonical K\"{a}hler potential with
\textit{minimal coupling} to gravity can resolve the tachyonic instability but
runs into the -problem. We suggest a model which is free of the
-problem due to an additional coupling in the K\"{a}hler potential which
is allowed by the Standard Model gauge group. This induces directions in the
potential which we call K-flat. For a certain value of the new coupling in the
(N)MSSM, the K\"{a}hler potential is special, because it can be associated with
a certain shift symmetry for the Higgs doublets, a generalization of the shift
symmetry for singlets in earlier models. We find that K-flat direction has
This shift symmetry is broken by interactions coming from
the superpotential and gauge fields. This direction fails to produce successful
inflation in the MSSM but produces a viable model in the NMSSM. The model is
specifically interesting in the Peccei-Quinn (PQ) limit of the NMSSM. In this
limit the model can be confirmed or ruled-out not just by cosmic microwave
background observations but also by axion searches.Comment: matches the published version at JCA
Cystic lymphangioma of the lesser sac presenting as acute appendicitis: A case report
Intra-abdominal lymphangiomas usually present by 2 years of age and are uncommon in adults. Cystic lymphagiomas arising from the lesser sac are even more uncommon. We report an unusual case of a lesser sac cystic lymphangioma presenting as acute appendicitis. A 21 year old female was admitted with pyrexia, right iliac fossa tenderness and an elevated C-reactive protein (CRP). At laparotomy, a large fluid filled cystic lesion was observed occupying the right side of the abdominal cavity. The lesion was excised in its entirety and histological diagnosis confirmed lymphangioma. The patient remains well with no evidence of recurrence 1 year post resection
A systematic review of treatment for patients with burning mouth syndrome.
BACKGROUND: Burning mouth syndrome is a chronic idiopathic intractable intraoral dysaesthesia that remains a challenge to clinicians due to its poorly understood pathogenesis and inconsistent response to various treatments. AIM: This review aimed to study the short- (≤3 months) and long-term (>3 months) effectiveness and sustainable benefit of different burning mouth syndrome treatment strategies and the associated side effects. MATERIALS AND METHODS: Randomised controlled trials of burning mouth syndrome treatment compared with placebo or other interventions with a minimum follow up of 2 months were searched from the PubMed, Embase and Cochrane database (published to July 2020). RESULTS: Twenty-two studies were selected based on the inclusion and exclusion criteria and analysed. Nine categories of burning mouth syndrome treatment were identified: Anticonvulsant and antidepressant agents, phytomedicine and alpha lipoic acid supplements, low-level laser therapy, saliva substitute, transcranial magnetic stimulation, and cognitive behaviour therapy. Cognitive behaviour therapy, topical capsaicin and clonazepam, and laser therapy demonstrated favourable outcome in both short- and long-term assessment. Phytomedicines reported a short-term benefit in pain score reduction. The pooled effect of alpha lipoic acid (ALA) pain score improvement was low, but its positive effects increased in long term assessment. CONCLUSION: A more significant volume in terms of sample size, multi-centres, and multi-arm comparison of therapeutic agents with placebo and longitudinal follow-up studies is recommended to establish a standardised burning mouth syndrome treatment protocol. Further studies are required to assess the analgesic benefits of topical clonazepam and capsaicin, alternative medicines with neurodegenerative prevention capability and psychology support in treating burning mouth syndrome and reducing systemic adverse drug reactions.Registration International Prospective Register of Systematic Reviews (PROSPERO):Protocol ID - CRD42020160892
- …