64 research outputs found

    The Application of the Cognitive Radio in the Aviation Communication Spectrum Management

    Get PDF
    AbstractIt is concerned that the aviation communication system is interfered by the inner and outside interference. Because of the electromagnetic spectrum is limited, it must be controlled and managed in order to use in aviation communication. The cognitive radio (CR) can perceive the electromagnetic environment automatically, search the spectrum holes, and adjust the signal parameters of both sides by communication protocols and algorithms to best situation. This paper discusses the CR and the application in the spectrum management of aviation communications

    Toxic effects of iron oxide nanoparticles on human umbilical vein endothelial cells

    Get PDF
    Iron oxide nanoparticles (IONPs) have been employed for hyperthermia treatments, stem cell therapies, cell labeling, and imaging modalities. The biocompatibility and cytotoxic effects of iron oxide nanoparticles when used in biomedical applications, however, are an ongoing concern. Endothelial cells have a critical role in this research dealing with tumors, cardiovascular disease and inflammation. However, there is little information dealing with the biologic effects of IONPs on the endothelial cell. This paper deals with the influence of dextran and citric acid coated IONPs on the behavior and function of human umbilical vein endothelial cells (HUVECs). After exposing endothelial cells to IONPs, dose-dependent effects on HUVECs viability, cytoskeleton and function were determined. Both citric acid and dextran coated particles appeared to be largely internalized by HUVECs through endocytosis and contribute to eventual cell death possibly by apoptosis. Cytoskeletal structures were greatly disrupted, as evidenced by diminished vinculin spots, and disorganized actin fiber and tubulin networks. The capacity of HUVECs to form a vascular network on Matrigelâ„¢ diminished after exposure to IONPs. Cell migration/invasion were inhibited significantly even at very low iron concentrations (0.1 mM). The results of this study indicate the great importance of thoroughly understanding nanoparticle-cell interactions, and the potential to exploit this understanding in tumor therapy applications involving IONPs as thermo/chemoembolization agents

    Research on Water Absorption and Frost Resistance of Concrete Coated with Different Impregnating Agents for Ballastless Track Structure

    Get PDF
    In consideration of performance requirement of ballastless track concrete in cold regions of China, 3 types of commercially available impregnating agents were employed to research their effect on water absorption and frozen resistance of concrete, containing silanes, potassium silicate and osmotic curing agent. The results presented that coating silanes was the most effective on the reduction of water absorption among all employed impregnating agents, because of the most significant character change of concrete surface from hydrophilicity to hydrophobicity which could be proved by the contact angle test of concrete. The promotion on frozen resistance of concrete was not as significant as that for water absorption by coating 3 commercially available types of impregnant agents, because of the spalling damage on concrete surface during the freezing-thawing cycles

    Passive immunotherapy for influenza A H5N1 virus infection with equine hyperimmune globulin F(ab')(2 )in mice

    Get PDF
    BACKGROUND: Avian influenza virus H5N1 has demonstrated considerable pandemic potential. Currently, no effective vaccines for H5N1 infection are available, so passive immunotherapy may be an alternative strategy. To investigate the possible therapeutic effect of antibody against highly pathogenic H5N1 virus on a mammal host, we prepared specific equine anti-H5N1 IgGs from horses vaccinated with inactivated H5N1 virus, and then obtained the F(ab')(2 )fragments by pepsin digestion of IgGs. METHODS: The horses were vaccinated with inactivated H5N1 vaccine to prepare anti-H5N1 IgGs. The F(ab')(2 )fragments were purified from anti-H5N1 hyperimmune sera by a protocol for 'enhanced pepsin digestion'. The protective effect of the F(ab')(2 )fragments against H5N1 virus infection was determined in cultured MDCK cells by cytopathic effect (CPE) assay and in a BALB/c mouse model by survival rate assay. RESULTS: By the protocol for 'enhanced pepsin digestion', total 16 g F(ab')(2 )fragments were finally obtained from one liter equine antisera with the purity of over 90%. The H5N1-specific F(ab')(2 )fragments had a HI titer of 1:1024, and the neutralization titre of F(ab')(2 )reached 1: 2048. The in vivo assay showed that 100 μg of the F(ab')(2 )fragments could protect BALB/c mice infected with a lethal dose of influenza H5N1 virus. CONCLUSION: The availability of highly purified H5N1-specific F(ab')(2 )fragments may be promising for treatment of influenza H5N1 infection. Our work has provided experimental support for the application of the therapeutic equine immunoglobulin in future large primate or human trials

    Short-Term Wind Speed Prediction Using EEMD-LSSVM Model

    Get PDF
    Hybrid Ensemble Empirical Mode Decomposition (EEMD) and Least Square Support Vector Machine (LSSVM) is proposed to improve short-term wind speed forecasting precision. The EEMD is firstly utilized to decompose the original wind speed time series into a set of subseries. Then the LSSVM models are established to forecast these subseries. Partial autocorrelation function is adopted to analyze the inner relationships between the historical wind speed series in order to determine input variables of LSSVM models for prediction of every subseries. Finally, the superposition principle is employed to sum the predicted values of every subseries as the final wind speed prediction. The performance of hybrid model is evaluated based on six metrics. Compared with LSSVM, Back Propagation Neural Networks (BP), Auto-Regressive Integrated Moving Average (ARIMA), combination of Empirical Mode Decomposition (EMD) with LSSVM, and hybrid EEMD with ARIMA models, the wind speed forecasting results show that the proposed hybrid model outperforms these models in terms of six metrics. Furthermore, the scatter diagrams of predicted versus actual wind speed and histograms of prediction errors are presented to verify the superiority of the hybrid model in short-term wind speed prediction

    Deep Learning and Dempster-Shafer Theory Based Insider Threat Detection

    Get PDF
    Organizations' own personnel now have a greater ability than ever before to misuse their access to critical organizational assets. Insider threat detection is a key component in identifying rare anomalies in context, which is a growing concern for many organizations. Existing perimeter security mechanisms are proving to be ineffective against insider threats. As a prospective filter for the human analysts, a new deep learning based insider threat detection method that uses the Dempster-Shafer theory is proposed to handle both accidental as well as intentional insider threats via organization's channels of communication in real time. The long short-term memory (LSTM) architecture is applied to a recurrent neural network (RNN) in this work to detect anomalous network behavior patterns. Furthermore, belief is updated with Dempster's conditional rule and utilized to fuse evidence to achieve enhanced prediction. The CERT Insider Threat Dataset v6.2 is used to train the behavior model. Through performance evaluation, our proposed method is proven to be effective as an insider threat detection technique

    Study on the adaptability and optimization of boom replacement methods for suspension bridges

    Get PDF
    To ensure the safe operation of bridges, the study of methods and techniques for boom replacement has become a crucial aspect of the scientific maintenance of suspension bridges. This study focuses on analyzing the bridge responses and evaluating the applicability of three different boom replacement methods: single-point, three-point and five-point, using finite element calculations. A sea-crossing suspension bridge is taken as a case study to simulate the process of boom replacement using temporary booms. Consequently, the optimal replacement method for booms of varying lengths is determined. Meanwhile, this research proposes a quantitative basis for classifying boom lengths based on calculation data and analysis results to determine the suitable boom lengths for different replacement methods. Besides, a comparison of the relationship between the force transmission efficiency of temporary booms and boom length reveals that longer booms exhibit lower force transmission efficiency, with the efficiency decreasing at a faster rate as boom length increases. Overall, these findings provide a theoretical basis for the study of boom replacement in suspension bridges
    • …
    corecore