Optimization of palm oil physical refining process for reduction of 3-monochloropropane-1,2-diol (3-MCPD) ester formation

The reduction of 3-monochloropropane-1,2-diol (3-MCPD) ester formation in refined palm oil was achieved by incorporation of additional processing steps in the physical refining process to remove chloroester precursors prior to the deodorization step. The modified refining process was optimized for the least 3-MCPD ester formation and acceptable refined palm oil quality using response surface methodology (RSM) with five processing parameters: water dosage, phosphoric acid dosage, degumming temperature, activated clay dosage, and deodorization temperature. The removal of chloroester precursors was largely accomplished by increasing the water dosage, while the reduction of 3-MCPD esters was a compromise in oxidative stability and color of the refined palm oil because some factors such as acid dosage, degumming temperature, and deodorization temperature showed contradictory effects. The optimization resulted in 87.2% reduction of 3-MCPD esters from 2.9 mg/kg in the conventional refining process to 0.4 mg/kg, with color and oil stability index values of 2.4 R and 14.3 h, respectively

Factors influencing employee retention of academic home tutors in a private school

This study’s goal is to investigate the links between pay and benefits, worklife balance, professional development, and employee retention among academic home tutors in a Malaysian private school. Data from 80 respondents from this private school were gathered using a quantitative survey method. Statistical package for social science (SPSS) was employed throughout the study to analyze the data. The study results showed that salary & compensation and career enhancement positively correlate with employee retention. Meanwhile, work-life balance was not statistically linked with employee retention. The management should revise the human resource management practices by including these elements. The management should design salary & compensation packages that fit with individual knowledge, capabilities, and performance. The management may also consider offering flexible work schedules, such as training, mentoring, job mobility, and a reduction in working hours, as well as wellness assistance, such as counselling services and health and wellness initiatives. This will give employees the chance to advance their careers

Personality traits and job performance among academic staff in a private academic institution

This study investigates the association between the personality traits of academic staff members and their job performance in a Malaysian private educational institution. The personality traits were based on the Big Five model, which has five dimensions: openness to experience, conscientiousness, extraversion, agreeableness, and neuroticism. About 110 participants from this institution were surveyed using a quantitative questionnaire, and their data were gathered. Throughout the study, the data were examined utilizing multiple regression analysis and factor analysis. According to the study’s findings, conscientiousness, and openness to experience significantly positively affect job performance. However, it was determined that extraversion, agreeableness, and neuroticism were not statistically significant and had no connection to job performance. As a result, in this institution, openness to experience is the most essential predictor of job performance. The findings of this study showed the management that openness to experience and conscientiousness are crucial for improving job performance inside the institution. Therefore, the management should pay more attention to these areas and recruit new employees with openness to experience and conscientious personality traits

Exploring lifelong learning outcomes among adult learners via goal orientation and information literacy self-efficacy

This study intends to explore the relationship between goal orientation, information literacy self-efficacy and lifelong learning outcomes of the adult learners. This study focuses on adult learners as they are actively participating in the development of the country socio-economy and recognized as the potential contributors towards the generation of knowledge-based economy. The findings of this study revealed that there was a significant relationship between mastery goal orientation and lifelong learning. However, information literacy self-efficacy was found to be a predictor instead of a moderator in the model. It is suggested that suitable and appropriate learning methods such as problem-based learning, case scenario presentations, portfolios and clinical debates can be designed specifically to facilitate adult learners’ mastery goal learning motivation in promoting lifelong learning. In addition, training and retraining to equip adult learners with new information literacy skills so as to keep up their self-efficacy level will definitely enhance lifelong learning. This study provides a database on the impact of goal orientation and information literacy self-efficacy towards lifelong learning in implementing policy formation, educational structure redesign and human capital development. As such, suitable and appropriate learning methods such as problem-based learning, case scenario presentations, portfolios and clinical debates can be designed specifically to facilitate student learning motivation in the classroom

Extraction and physicochemical properties of low free fatty acid crude palm oil.

Response surface methodology was applied to optimize the pre-treatment of oil palm (Elaeis guineensis) fruit spikelets before oil extraction. The treatment applied was drying at different times and temperatures. The dried spikelets were then subjected to mechanical processes and crude oil was extracted. A central composite design was employed to study the responses, namely percentage of free fatty acids (FFA) and oil yield, and the optimum conditions for minimum FFA and maximum oil yield were identified from their respective contour plots. It was concluded that the pre-treatment should be carried out for 12.8 h at 66.8 °C. Under the optimum conditions, the corresponding response values for FFA and oil yield were 1% and 33.6%, respectively. Some of the physicochemical properties of the extracted oil were then determined. The low free fatty acid crude palm oil exhibited good physicochemical properties and could be useful for industrial applications

What influences urbanites’ mobile payment adoption? The moderating roles of demographic divides

This study examines the moderating roles of demographic divides, such as gender, income, and education, on factors influencing mobile payment adoption among urbanites in Malaysia. An online survey questionnaire was used for data collection, which yielded 428 responses. PLS-SEM was employed to assess validity, reliability, hypothesis testing, and PLS-MGA of the study constructs. The findings of this paper revealed that perceived security, perceived ease of use, perceived usefulness, and trust were significantly related to mobile payment adoption. Gender, income, and education were found to moderate the results. This research provides important information to service providers, banking institutions, and the government to understand factors influencing mobile payment adoption and consider demographic characteristics of gender, income, and education in mobile payment adoption. This study explains the moderating effects of demographic divides on mobile payment adoption among urbanites that are rarely addressed in Malaysia

Physicochemical and sensory analyses of high fibre bread incorporated with corncob powder

The primary objectives of the present work were to produce corncob powder (CCP) from corncobs and incorporate the CCP into bread formulation in order to develop high fibre bread, and to investigate the physicochemical and sensory properties of the produced high fibre bread (HFB). The corncobs were collected and washed before they underwent the grinding and drying processes. The obtained CCP was incorporated into the bread formulation in three different proportions (5, 10 and 20%) to partially substitute bread flour in the formulation. All three bread samples and the control (0% CCP in the formulation) were analysed to obtain their physicochemical and sensory properties. The incorporation of CCP significantly affected the texture, colour and volume attributes of the produced breads. Increasing the content of CCP in the formulation was found to be responsible for firmer, smaller and darker bread loaves as compared to the composite bread samples. The bread formulation incorporated with 10% CCP had the highest mean scores (7.00) of overall acceptability among all the other formulations, and it was comparable to the commercial breads in the current market

Changes in oxidation indices and minor components of low free fatty acid and freshly extracted crude palm oils under two different storage conditions

This article reports on the changes of oxidation indices and minor components of low free fatty acid (FFA) and freshly extracted crude palm oils after storage at ambient (28 ± 1 C) and 60 C for 77 days. The changes in peroxide value (PV), FFA, extinction coefficient at 233 and 269 nm (K 233 and K 269), bleachability index (DOBI), carotene and vitamin E contents were monitored. PV, FFA, K 233 and K 269 of both oil samples increased as storage progressed while the values of carotene and vitamin E contents decreased. At the end of storage period at 60 °C, the carotene content of low FFA crude palm oil was 4.24 ppm. The storage conditions used led to the loss of entire vitamin E fractions of both oil samples as well as a reduction in DOBI values except for freshly extracted crude palm oil stored at ambient temperature

Disease-associated XMRV sequences are consistent with laboratory contamination.

BACKGROUND: Xenotropic murine leukaemia viruses (MLV-X) are endogenous gammaretroviruses that infect cells from many species, including humans. Xenotropic murine leukaemia virus-related virus (XMRV) is a retrovirus that has been the subject of intense debate since its detection in samples from humans with prostate cancer (PC) and chronic fatigue syndrome (CFS). Controversy has arisen from the failure of some studies to detect XMRV in PC or CFS patients and from inconsistent detection of XMRV in healthy controls. RESULTS: Here we demonstrate that Taqman PCR primers previously described as XMRV-specific can amplify common murine endogenous viral sequences from mouse suggesting that mouse DNA can contaminate patient samples and confound specific XMRV detection. To consider the provenance of XMRV we sequenced XMRV from the cell line 22Rv1, which is infected with an MLV-X that is indistinguishable from patient derived XMRV. Bayesian phylogenies clearly show that XMRV sequences reportedly derived from unlinked patients form a monophyletic clade with interspersed 22Rv1 clones (posterior probability >0.99). The cell line-derived sequences are ancestral to the patient-derived sequences (posterior probability >0.99). Furthermore, pol sequences apparently amplified from PC patient material (VP29 and VP184) are recombinants of XMRV and Moloney MLV (MoMLV) a virus with an envelope that lacks tropism for human cells. Considering the diversity of XMRV we show that the mean pairwise genetic distance among env and pol 22Rv1-derived sequences exceeds that of patient-associated sequences (Wilcoxon rank sum test: p = 0.005 and p < 0.001 for pol and env, respectively). Thus XMRV sequences acquire diversity in a cell line but not in patient samples. These observations are difficult to reconcile with the hypothesis that published XMRV sequences are related by a process of infectious transmission. CONCLUSIONS: We provide several independent lines of evidence that XMRV detected by sensitive PCR methods in patient samples is the likely result of PCR contamination with mouse DNA and that the described clones of XMRV arose from the tumour cell line 22Rv1, which was probably infected with XMRV during xenografting in mice. We propose that XMRV might not be a genuine human pathogen

HIV-1 Vpr antagonizes innate immune activation by targeting karyopherin-mediated NF-κB/IRF3 nuclear transport.

HIV-1 must replicate in cells that are equipped to defend themselves from infection through intracellular innate immune systems. HIV-1 evades innate immune sensing through encapsidated DNA synthesis and encodes accessory genes that antagonize specific antiviral effectors. Here, we show that both particle associated, and expressed HIV-1 Vpr, antagonize the stimulatory effect of a variety of pathogen associated molecular patterns by inhibiting IRF3 and NF-κB nuclear transport. Phosphorylation of IRF3 at S396, but not S386, was also inhibited. We propose that, rather than promoting HIV-1 nuclear import, Vpr interacts with karyopherins to disturb their import of IRF3 and NF-κB to promote replication in macrophages. Concordantly, we demonstrate Vpr-dependent rescue of HIV-1 replication in human macrophages from inhibition by cGAMP, the product of activated cGAS. We propose a model that unifies Vpr manipulation of nuclear import and inhibition of innate immune activation to promote HIV-1 replication and transmission