PENGARUH CITRA MEREK, KUALITAS PRODUK DAN DESAIN PRODUK TERHADAP KEPUTUSAN PEMBELIAN LUWAK WHITE COFFEE DI KOTA BATAM

Various initiatives were carried out by the company to boost product sales to meetconsumer demand. When a person recognizes a need in general and wants inparticular, the buying process occurs. The difference between the desired state andthe existing condition begins to register in the person's consciousness. Becauseeveryone has different points of reference and attitudes towards goods, one's buyingbehavior can be said to be unique. Brand Image, Product Quality and Product Designare existing factors that can influence purchasing decisions. The sampling techniqueuses simple random sampling. For data collection purposes, the researcherdistributed questionnaires, which contained a list of questions that had to beanswered by the participants. The method used in the findings contained in this studyis a quantitative-based research by conducting multiple linear analysis. The results ofresearch based on a study will certainly be able to prove that brand image, productquality and product design have a significant effect on purchasing decisions for LuwakWhite Coffee in Batam City.Various initiatives were carried out by the company to boost product sales to meet consumer demand. When a person recognizes a need in general and wants in particular, the buying process occurs. The difference between the desired state and the existing condition begins to register in the person's consciousness. Because everyone has different points of reference and attitudes towards goods, one's buying behavior can be said to be unique. Brand Image, Product Quality and Product Design are existing factors that can influence purchasing decisions. The sampling technique uses simple random sampling. For data collection purposes, the researcher distributed questionnaires, which contained a list of questions that had to be answered by the participants. The method used in the findings contained in this study is a quantitative-based research by conducting multiple linear analysis. The results of research based on a study will certainly be able to prove that brand image, product quality and product design have a significant effect on purchasing decisions for Luwak White Coffee in Batam City

Effect of coitus at term on length of gestation, induction of labor, and mode of delivery.

OBJECTIVE: To determine coital incidence at term and to estimate its effect on labor onset and mode of delivery. METHODS: Healthy women with uncomplicated pregnancies and established gestational age were recruited to keep a diary of coital activity from 36 weeks of gestation until birth and to answer a short questionnaire. Two hundred women with complete coital diaries were available for analysis. Outcome measures include coitus, postdate pregnancy (defined as pregnancy beyond the estimated date of confinement), gestational length of at least 41 weeks, labor induction at 41 weeks of gestation, and mode of delivery. RESULTS: Reported sexual intercourse at term was influenced by a woman's perception of coital safety, her ethnicity, and her partner's age. After multivariable logistic regression analysis controlling for the women's ethnicity, education, occupation, perception of coital safety, and partner's age, coitus at term remained independently associated with reductions in postdate pregnancy (adjusted odds ratio [AOR] 0.28, 95% confidence interval [CI] 0.13-0.58, P = .001), gestational length of at least 41 weeks (AOR 0.10, 95% CI 0.04-0.28, P < .001), and requirement for labor induction at 41 weeks of gestation (AOR 0.08, 95% CI 0.03-0.26, P < .001). At 39 weeks of gestation, 5 (95% CI 3.3-10.3) couples needed to have intercourse to avoid one woman having to undergo labor induction at 41 weeks of gestation. Coitus at term had no significant effect on operative delivery (adjusted P = .15). CONCLUSION: Reported sexual intercourse at term was associated with earlier onset of labor and reduced requirement for labor induction at 41 weeks

Analysis of peripheral blood of ovarian cancer patients indicates higher sub-populations of natural killer and B cells compared to healthy volunteers

Ovarian cancer is a challenging disease to treat, and one of the potential treatments is by immunotherapy. NK cells have been shown to play a role in slowing tumour progression and cancer development. This study aims to investigate the numbers of NK cells and other lymphocyte sub-populations in ovarian cancer and their impact on ovarian cancer clinical outcome. This project aims to study the significance of different lymphocyte populations, particularly NK cells, involved in the peripheral blood of ovarian cancer patients. Venal blood was drawn from ovarian cancer patients before chemotherapy. PBMCs were isolated from 13 ovarian cancer patients and 11 age-matched healthy volunteers. Immunophenotyping was performed using a commercial kit to quantify the lymphocyte populations and RNA isolation performed to examine the expression of KIR genes using reverse transcription polymerase chain reaction. Immunophenotyping of PBMC was successfully performed on 13 ovarian cancer patients and 11 healthy controls. Significant increases in the mean of peripheral NK cells and B cells were found in ovarian cancer patients as compared to the healthy controls (P=0.0559). No other significant results were obtained for C D4 and CD8 lymphocytes. There was significant increase in numbers of NK cells and B cells in ovarian cancer patients as compared to the healthy volunteers. These results should be pursued with a larger sample size with the hopes of finding a significant difference between the two groups and to provide a keener insight into are promising preliminary results the immune defence against ovarian cancer

Charged Particle Beam Injection into Magnetically Confined Plasmas

As the principles underpinning magnetic confinement are contrary to allowing significant heat flow via charged particles into or out of a magnetically confined plasma, the approach of charged particle beam injection has been largely overlooked. The method of magnetic orbital angular momentum beam acceleration, developed by the PTOLEMY experiment, provides a new avenue for injecting charged particle beams into high magnetic field regions. Initial simulations show how this novel acceleration method can yield charge, mass, and heat flow into toroidal magnetic fields with important implications for fusion energy science. This chapter will review this new method in the context of charged particle beam injection methods and the relevance of these tools for plasma and fusion science

Expression of killer cell immunoglobulin-like receptors (KIR) in sex-associated malignancies

Introduction: Sex shapes immune response with possible consequence on tumor immune escape. Acute lymphoblastic leukemia (ALL) predominates in males while ovarian cancer (OC) occurs in females. NK cells essential for tumor killing may have male preponderance. Association of sex, NK cell activity and malignancies is unclear. We hypothesize that sex differentially affects KIR expressions in sex-biased cancers. Method: Expression of inhibitory (KIR2DL1-5 and KIR3DL1-3) and activating (KIR2DS1-2 and 4-5 and KIR3DS1) genes in B-, T-cell ALL, OC and normal controls were determined by reverse-transcription polymerase-chain-reaction. Result: All normal males (but not females) expressed the framework genes and generally maintained haplotype A, except KIR3DL1. Normal females expressed more activating KIRs. Frequencies of KIR2DL1, 2DL4 and 2DS2 were significantly reduced among ovarian cancer patients. Sex difference in frequencies of KIR expression was not detected in ALL as majority were undetectable except framework gene KIR3DL2, was more frequent among T-ALL. Conclusion: Cancers may be associated with reduced KIR expression and influence of sex requires investigation

Low-mass dark matter search results from full exposure of PandaX-I experiment

We report the results of a weakly-interacting massive particle (WIMP) dark matter search using the full 80.1\;live-day exposure of the first stage of the PandaX experiment (PandaX-I) located in the China Jin-Ping Underground Laboratory. The PandaX-I detector has been optimized for detecting low-mass WIMPs, achieving a photon detection efficiency of 9.6\%. With a fiducial liquid xenon target mass of 54.0\,kg, no significant excess event were found above the expected background. A profile likelihood analysis confirms our earlier finding that the PandaX-I data disfavor all positive low-mass WIMP signals reported in the literature under standard assumptions. A stringent bound on the low mass WIMP is set at WIMP mass below 10\,GeV/c$^2$, demonstrating that liquid xenon detectors can be competitive for low-mass WIMP searches.Comment: v3 as accepted by PRD. Minor update in the text in response to referee comments. Separating Fig. 11(a) and (b) into Fig. 11 and Fig. 12. Legend tweak in Fig. 9(b) and 9(c) as suggested by referee, as well as a missing legend for CRESST-II legend in Fig. 12 (now Fig. 13). Same version as submitted to PR