Too Hot to Handle: An Evaluation of the Effect of Thermal Visual Representation on User Grasping Interaction in Virtual Reality

Influence of interaction fidelity and rendering quality on perceived user experience have been largely explored in Virtual Reality (VR). However, differences in interaction choices triggered by these rendering cues have not yet been explored. We present a study analysing the effect of thermal visual cues and contextual information on 50 participants' approach to grasp and move a virtual mug. This study comprises 3 different temperature cues (baseline empty, hot and cold) and 4 contextual representations; all embedded in a VR scenario. We evaluate 2 different hand representations (abstract and human) to assess grasp metrics. Results show temperature cues influenced grasp location, with the mug handle being predominantly grasped with a smaller grasp aperture for the hot condition, while the body and top were preferred for baseline and cold conditions

Un entraînement excentrique excessif chez des souris carencées en vitamine D conduit à une perte de capacités physiques, une atrophie musculaire et une inflammation systémique

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IMMUNOMODULATION DU MICRO-ENVIRONNEMENT TUMORAL MAMMAIRE : L'EXERCICE PHYSIQUE CONTREBALANCE L'EFFET TOLÉROGÈNE DE LA VITAMINE D

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Vitamin D deficiency contributes to overtraining syndrome in excessive trained C57BL /6 mice

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Immunonutrition stimulates immune functions and antioxidant defense capacities of leukocytes in radiochemotherapy-treated head & neck and esophageal cancer patients: A double-blind randomized clinical trial

This clinical trial has been registered on ClinicalTrial.gov website: NCT00333099. (C) 2014 Elsevier Ltd and European Society for Clinical Nutrition and MetabolismThis work was supported by the Fonds National d'Amenagement et de Developpement du Territoire (FNADT) and European Regional Development Fund (ERDF)Background: Immunonutrition has been reported to improve the immune status of perioperative cancer patients, thereby reducing complications and length of hospital stay. Aim: This study aimed to assess whether immunonutrition enriched in arginine, EPA & DHA and nucleotides could impact the immune cells responses in head & neck and esophageal cancer patients treated by radiochemotherapy (RCT). Methods: A double-blind clinical trial was carried out in 28 patients randomized into two groups, receiving either an immunomodulating enteral nutrition formula (IEN, n = 13, Impact (R), Nestle) or an isoenergetic isonitrogenous standard enteral nutrition formula (SEN, n = 15) throughout RCT (5-7 weeks). After isolation from whole blood, immune cells metabolism and functions were assessed at the beginning (Db) and at the end (De) of RCT. Results: Immunonutrition maintained CD4(+)/CD8(+) T-Iymphocyte counts ratio and CD3 membrane expression between Db and De. Polymorphonuclear cells CD62L and CD15 densities and ROS production were increased in IEN patients. Peripheral blood mononuclear cells (PBMC) production of proinflammatory prostaglandin-E2 was stable in IEN patients and lower than in SEN patients at De. Genes coding for immune receptors, antioxidant enzymes and NADPH oxidase subunits were overexpressed in the PBMC of LEN vs SEN patients at De. Conclusion: Immunonutrition can enhance immune cell responses through the modulation of their phenotypes and functions. By modulating the gene expression of immune cells, immunonutrition could make it easier for the organism to adapt to the systemic inflammation and oxidative stress induced by RCT. Clinical trial registration: This clinical trial has been registered on ClinicalTrial.gov website: NCT00333099. (C) 2014 Elsevier Ltd and European Society for Clinical Nutrition and Metabolis