Symptomatic Porphyria

The administration of hexachlorobenzene (HCB) to rats for periods up to 67 days resulted in the development of gross cytoplasmic vacuolation and the formation of cytoplasmic inclusions. Some of the inclusions consisted of slender tubular structures about 200 A in diameter. Although it was suspected that the inclusions represented precipitated porphyrins, proof of this could not be obtained. The prior administration of iron to some of the animals before commencing feeding with HCB resulted in a more extensive development of the lesions in the liver, and this could account for the higher levels of excreted porphyrins in the iron-laden animals.S. Afr. Med. J., 48, 1833 (1974)

The effect of iron and aluminium on transferrin and other serum proteins as revealed by isoelectric focusing gel electrophoresis.

GesondheidswetenskappeChemiese PatologiePlease help us populate SUNScholar with the post print version of this article. It can be e-mailed to: [email protected]

Serum concentrations of some metals and steroids in patients with chronic fatigue syndrome with reference to neurological and cognitive abnormalities.

GesondheidswetenskappeInterne GeneeskundePlease help us populate SUNScholar with the post print version of this article. It can be e-mailed to: [email protected]

Porfiria cutânea tardia Porphyria cutanea tarda

Trata-se de revisão sobre a porfiria cutânea tardia em que são abordados a fisiopatogenia, as características clínicas, as doenças associadas, os fatores desencadeantes, a bioquímica, a histopatologia, a microscopia eletrônica, a microscopia de imunofluorescência e o tratamento da doença.<br>This is a review article of porphyria cutanea tarda addressing pathophysiology, clinical features, associated conditions, triggering factors, biochemistry, histopathology, electronic microscopy, immunofluorescence microscopy and treatment of the disease