腸管におけるGPR120シグナルの阻害は高脂肪食摂取下のインスリン抵抗性および脂肪肝を軽減する

京都大学新制・課程博士博士(医学)甲第24880号医博第5014号京都大学大学院医学研究科医学専攻(主査)教授 長船 健二, 教授 江木 盛時, 教授 妹尾 浩学位規則第4条第1項該当Doctor of Medical ScienceKyoto UniversityDFA

Ultrafast spin-flip exciton conversion and narrowband sky-blue luminescence in a fused polycyclic selenaborin emitter

Thermally activated delayed fluorescence (TADF) materials with high photoluminescence quantum yields and fast reverse intersystem crossing (RISC) capabilities are highly desirable for applications in high-efficiency organic light-emitting diodes. Herein, we report the synthesis as well as structural and photophysical properties of 5,9-diselena-13b-boranaphtho[3,2,1-de]anthracene (SeBSe) as a narrowband-emissive TADF material. The incorporation of two selenium atoms into the boron-fused pentacyclic π-core results in a small singlet–triplet energy gap (ΔEST) and thereby significant TADF properties. Moreover, theoretical calculations revealed a noticeable spin-orbit coupling enhancement between the singlet and triplet manifolds in SeBSe by virtue of the heavy-atom effect of selenium atoms. Consequently, SeBSe allows ultrafast spin-flip RISC with the rate constant surpassing 108 s−1, which far exceeds the corresponding fluorescence radiative decay rate (∼106 s−1), enabling an ideal singlet–triplet superimposed excited state