Incidence of and improvement in inappropriate parental behaviors of mothers with young children: a retrospective cohort study conducted in collaboration with a local government

博士（医学）福島県立医科大

Boundary Scattering in Ballistic Graphene

We report magnetotransport measurements in ballistic graphene/hexagonal boron nitride mesoscopic wires where the charge carrier mean free path is comparable to wire width $W$. Magnetoresistance curves show characteristic peak structures where the peak field scales with the ratio of cyclotron radius $R_\textrm{c}$ and wire width $W$ as $W/R_\textrm{c} = 0.9 \pm 0.1$, due to diffusive boundary scattering. The obtained proportionality constant between $R_\textrm{c}$ and $W$ differs from that of a classical semiconductor 2D electron system where $W/R_\textrm{c} = 0.55$.Comment: 14 pages, 4 figure

Comprehensive treatment for severe periodontitis with pathologic tooth migration−related bimaxillary protrusion : A case report with 3-year follow-up

Background: Patients with severe periodontitis often experience pathologic tooth migration (PTM), which impairs esthetics and leads to occlusal disharmony (e.g., premature contacts and/or traumatic occlusion) that can further exacerbate periodontitis. Here, we describe a patient who exhibited severe periodontitis with PTM-related bimaxillary protrusion. This report includes 3-year clinical outcomes following periodontal regenerative therapy, implant-anchored orthodontic therapy, and implant prosthodontics intended to achieve both functional and esthetic improvements. Case Description: A 63-year-old woman presented with the chief complaint of upper anterior tooth mobility. Clinical examination revealed excessive tooth mobility, deep periodontal pockets, and infrabony defects in all teeth. All teeth exhibited PTM; the mandibular anterior teeth exhibited marked protrusion caused by the progression of periodontitis. After initial periodontal therapy, periodontal regenerative therapy was performed in all molar regions. At 9 and 6 months postoperatively, comprehensive orthodontic treatment was initiated for the mandible and maxilla, respectively, using orthodontic anchorage devices to achieve acceptable functional occlusion. After orthodontic treatment, staged guided bone regeneration was performed and dental implants were placed in the severely resorbed maxillary anterior ridge. This comprehensive treatment yielded favorable periodontal conditions, stable occlusion, and good esthetic outcomes. Practical Implications: Favorable esthetics, stable occlusion, and highly cleansable periodontal tissues were achieved with well-planned interdisciplinary and comprehensive treatment, although the patient had severe periodontitis and PTM-related bimaxillary protrusion

通塾が中学生の就寝時間や疲労感に与える影響に関する研究

To investigate the influence of attending juku on bedtime and cumulative fatigue symptoms, questionnaires were administered to 163 students in a junior high school in Aichi Prefecture. Cumulative fatigue were assessed by using the Cumulative Fatigue Symptoms Index (CFSI). The results were as follows : 1) Approximately 70 percent of students attended some kind of juku, 40 percent of which changed bedtime when attending juku. No tendency was found between the change in supper time and the change in bedtime. 2) As a result, in the group whose bedtime got late when attending juku, the average rates of those who complained of symptoms within chronic tiredness rose. On the other hand, in the group without attending juku the average rates of those who complained of symptoms within physical disorders, decreased vitality, decreased willingness to study, irritability were higher than those in the group attending juku. 3) The complaint rates of load and tiredness were high in the group who usually goes to bed after 0 a. m.. 4) Average rates of those who complained of symptoms within many categories were high in the group without attending juku and usually going to bed from 11 p. m. to 0 a. m. On the other hand, average rates of those who complained of symptoms within irritability were a little high in the group who usually goes to bed from 11 p. m. to 0 a. m. and got late bedtime with attending juku

A compact chaotic laser device with a two-dimensional external cavity structure

金沢大学理工研究域機械工学系We propose a compact chaotic laser device, which consists of a semiconductor laser and a two-dimensional (2D) external cavity for delayed optical feedback. The overall size of the device is within 230μm × 1 mm. A long time delay sufficient for chaos generation can be achieved with the small area by the multiple reflections at the 2D cavity boundary, and the feedback strength is controlled by the injection current to the external cavity. We experimentally demonstrate that a variety of output properties, including chaotic output, can be selectively generated by controlling the injection current to the external cavity. © 2014 AIP Publishing LLC

The 2006 November outburst of EG Aquarii: the SU UMa nature revealed

We report time-resolved CCD photometry of the cataclysmic variable EG Aquarii during the 2006 November outburst During the outburst, superhumps were unambiguously detected with a mean period of 0.078828(6) days, firstly classifying the object as an SU UMa-type dwarf nova. It also turned out that the outburst contained a precursor. At the end of the precursor, immature profiles of humps were observed. By a phase analysis of these humps, we interpreted the features as superhumps. This is the second example that the superhumps were shown during a precursor. Near the maximum stage of the outburst, we discovered an abrupt shift of the superhump period by ${\sim}$ 0.002 days. After the supermaximum, the superhump period decreased at the rate of $\dot{P}/P$=$-8.2{\times}10^{-5}$, which is typical for SU UMa-type dwarf novae. Although the outburst light curve was characteristic of SU UMa-type dwarf novae, long-term monitoring of the variable shows no outbursts over the past decade. We note on the basic properties of long period and inactive SU UMa-type dwarf novae.Comment: 9 pages, 7 figures, accepted for PAS

保健体育科の教育実習生に対する実習校の評価に関する研究 : 愛知県と他府県の比較を中心として

In this study a survey was made of the actual conditions in evaluating student apprentices in a teaching practicum of health and physical education as well as some factors affecting their evaluations. This research was carried out to evaluate 701 student apprentices in the teaching practicum of health and physical education in 1994 and 1995. A total of 588 students responded to the questionnaire (response rate of 90.6%) administered annually following the completion of their teaching practicum. The main results are as follows : The obvious difference between the evaluations in Aichi and in other prefectures is that the evaluations in Aichi are relatively stricter. One of the reasons for this regional difference may be attributed to a preferential treatment shown by apprentices\u27 former teachers to their students in their alma mater. For a fair and objective evaluation of student apprentices, the schools to which the students are sent should be allocated by the Board of Education. It is equally advisable that students\u27 leadership qualities be evaluated not by a single teacher but by a number of teachers. Using the evaluations by schools as a resource for judgment, the proper term of effective apprentice practice may be three weeks, instead of two, during which the students are to be in charge of at least 10 and hopefully about 20 class practice sessions

STING signalling is terminated through ESCRT-dependent microautophagy of vesicles originating from recycling endosomes

STING炎症シグナルの終結分子機構 --新規細胞内分解システムの発見--. 京都大学プレスリリース. 2023-03-14.Stimulator of interferon genes (STING) is essential for the type I interferon response against a variety of DNA pathogens. Upon emergence of cytosolic DNA, STING translocates from the endoplasmic reticulum to the Golgi where STING activates the downstream kinase TBK1, then to lysosome through recycling endosomes (REs) for its degradation. Although the molecular machinery of STING activation is extensively studied and defined, the one underlying STING degradation and inactivation has not yet been fully elucidated. Here we show that STING is degraded by the endosomal sorting complexes required for transport (ESCRT)-driven microautophagy. Airyscan super-resolution microscopy and correlative light/electron microscopy suggest that STING-positive vesicles of an RE origin are directly encapsulated into Lamp1-positive compartments. Screening of mammalian Vps genes, the yeast homologues of which regulate Golgi-to-vacuole transport, shows that ESCRT proteins are essential for the STING encapsulation into Lamp1-positive compartments. Knockdown of Tsg101 and Vps4, components of ESCRT, results in the accumulation of STING vesicles in the cytosol, leading to the sustained type I interferon response. Knockdown of Tsg101 in human primary T cells leads to an increase the expression of interferon-stimulated genes. STING undergoes K63-linked ubiquitination at lysine 288 during its transit through the Golgi/REs, and this ubiquitination is required for STING degradation. Our results reveal a molecular mechanism that prevents hyperactivation of innate immune signalling, which operates at REs