96 research outputs found

    Antiresorptive agent-related osteonecrosis of the jaw: Position Paper 2017 of the Japanese Allied Committee on Osteonecrosis of the Jaw

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    Antiresorptive agent-related osteonecrosis of the jaw (ARONJ) is an intractable, though rare, complication in cancer patients with bone metastases and patients with osteoporosis who are treated with antiresorptive agents, including bisphosphonates and denosumab. Despite the more than 10 years that have passed since the first cases of bisphosphonate-related osteonecrosis of the jaw (BRONJ) were reported, our understanding of the epidemiology and pathophysiology of ARONJ remains limited, and data supported by evidence-based medicine are still sparse. However, the diagnosis and staging of ARONJ, identification of risk factors, and development of preventive and therapeutic approaches have advanced significantly over the past decade. The Position Paper 2017 is an updated version of the Position Paper 2010 of the Japanese Allied Committee on Osteonecrosis of the Jaw, which now comprises six Japanese academic societies. The Position Paper 2017 describes a new diagnostic definition for ARONJ, as proposed by the American Association of Oral and Maxillofacial Surgeons (AAOMS), summarizes our current understanding of the pathophysiology of ARONJ based on a literature search, and suggests methods for physicians and dentists/oral surgeons to manage the disease. In addition, the appropriateness of discontinuing antiresorptive medications (drug holiday) before, during, and after invasive dental treatments is discussed extensively. More importantly, the manuscript also proposes, for the first time, the importance of interactive communication and cooperation between physicians and dentists/oral surgeons for the successful treatment of ARONJ. The Position Paper 2017 is intended to serve as a guide for improving the management of ARONJ patients in Japan

    TÉCNICAS PARA VISUALIZAR INFORMAÇÃO E EXTRAIR CONHECIMENTO DE BASES DE INFORMAÇÕES: ESTUDO DE CASO DAS PRODUÇÕES DOS PROFESSORES DO PPGI-UFES

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    A Visualização é uma parte muito importante para conseguir a compreensão real da informação e para extrair conhecimentos relevantes. Portanto, a técnica para visualizar a informação selecionada deve ser compatível com o conteúdo que se vai apresentar. A proposta desta dissertação é apresentar um site que integre diversas Técnicas de Visualização criadas, que sejam fáceis, rápidas, entendíveis, dinâmicas e adaptáveis, dos temas desenvolvidos pelos integrantes de um grupo de pesquisa, durante alguns períodos. Essas técnicas são construídas tomando por base principalmente as palavras-chave e títulos das Produções Bibliográficas, representando assim a evolução dos temas pesquisados ao longo do tempo, entre outras coisas
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