45 research outputs found

    The nonlinear contraction in probabilistic cone b-metric spaces with application to integral equation

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    The probabilistic cone b-metric space is a novel concept that we describe in this study along with some of its fundamental topological properties and instances. We also established the fixed point theorem for the probabilistic nonlinear Banach contraction mapping on this kind of spaces. Many prior findings in the literature are generalized and unified by our findings. In order to illustrate the basic theorem in ordinary cone b-metric spaces, some related findings are also provided with an application to integral equation

    Rosiglitazone decreases postprandial production of acylation stimulating protein in type 2 diabetics

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    <p>Abstract</p> <p>Background</p> <p>We evaluated plasma ASP and its precursor C3 in type 2 diabetic men with/without rosiglitazone (ROSI) treatment compared to healthy non-obese men. We tested (1) whether plasma ASP or C3 are altered postprandially in subcutaneous adipose tissue or forearm muscle effluent assessed by arteriovenous (A-V) differences in healthy lean men and older obese diabetic men and (2) whether treatment with ROSI changes the arteriovenous gradient of ASP and/or C3.</p> <p>Methods</p> <p>In this ongoing placebo-controlled, crossover, double-blinded study, AV differences following a mixed meal were measured in diabetic men (n = 6) as compared to healthy men (n = 9).</p> <p>Results</p> <p>Postprandial arterial and adipose venous TG and venous NEFA were increased in diabetics vs. controls (p < 0.05–0.0001). ROSI treatment decreased postprandial arterial TG (p < 0.001), adipose venous NEFA (p < 0.005), reduced postprandial glucose (p < 0.0001) and insulin concentrations (p < 0.006). In healthy men, there was no change in postprandial C3, but an increase in adipose venous ASP vs. arterial ASP (p < 0.02), suggesting ASP production, with no change in forearm muscle. In older, obese diabetic subjects, arterial C3 was greater than in controls (p < 0.001). Arterial C3 was greater than venous C3 (p < 0.05), an effect that was lost with ROSI treatment. In diabetics, postprandial venous ASP was greater than arterial (p < 0.05), indicating ASP production, an effect that was lost with ROSI treatment (p < 0.01).</p> <p>Conclusion</p> <p>Increased postprandial venous production of ASP is specific for adipose tissue (absent in forearm muscle). Increased postprandial C3 and ASP in diabetic subjects is consistent with an ASP resistant state, this state is partially normalized by treatment with ROSI.</p

    Matériau support des panneaux muraux fontaines en zellige marocain carreaux céramiques

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    Le domaine de la recherche dans les matériaux composites est encore nouveau dans les universités et les centres de recherche au Maroc. Les applications des matériaux composites dans les différentes branches industrielles couvrent divers secteur d’activités. L'objectif principal de ce travail est la valorisation des tables d'artisanat traditionnel, des panneaux muraux, fontaines en zellige marocain et carreaux céramiques en les rendant plus attrayants, plus légers et plus écologiques par l’élaboration des matériaux composites sur les critères «3E»: économique (sans énergie), écologique (procédé propre) et environnemental (recyclage et valorisation des déchets: la poudre de marbre, la pierre ponce usagée issue des industries de délavage...

    LA MANIFESTATION DE LA THEORIE DE LA HIERARCHISATION DES RESSOURCES DE FINANCEMENT CHEZ LES ENTREPRISES MAROCAINES COTEES

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    Le choix de financement d’une activité chez les entreprises, suit une hiérarchisation, suivant sa nature, qui peut être le résultat de décisions aléatoires, comme il peut suivre un formalisme théorique existant et répandu dans la littérature financière. Ce modeste travail teste les modes de financement tels quels sont hiérarchisés par la théorie du Pecking Order afin de vérifier la concordance théorique et pratique de cet apport scientifique.  

    The effect of Leonardite humic substances on the growth and vegetative propagation of saffron (Crocus sativus L.)

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    Le safran (Crocus sativus L.) est une espèce géophyte triploïde stérile (2n=3x=24) à floraison automnale et appartenant à la famille des Iridacées. Cette plante triploïde se propage par reproduction végétative par la formation de cormes filles à partir des cormes mère, car les fleurs sont stériles et ne produisent pas de graines viables. En fait, de nombreux facteurs entravent la propagation efficace du safran par cette pratique traditionnelle et les faibles taux de multiplication des cormes dans les conditions naturelles réduisent la productivité, limitant ainsi la disponibilité du matériel de plantation. Ainsi, l'objectif principal de ce travail est de tester l'effet des substances humiques (SH) sur la croissance et la multiplication végétative du safran. Les principaux résultats des essais indiquent que les SH améliorent la croissance et le développement du safran, et l'intensité de la réponse dépend de la concentration utilisée et du mode d'application. En fait, le traitement temporaire des cormes avec les SH (50 et 100 ppm) a amélioré la croissance des plantes et des cormes filles mais n'a pas d’effet significatif sur le nombre de pousses et de cormes filles.Saffron (Crocus sativus L.) is an autumn-flowering and sterile triploid (2n=3x=24) geophyte species that belong to the Iridaceae family. This triploid plant is propagated by vegetative reproduction through the formation of daughter corms from the mother corm, as the flowers are sterile and fail to produce viable seeds. In fact, many factors hamper the efficient propagation of saffron through this traditional practice and the low multiplication rates of daughter corms under natural conditions reduce productivity, thereby restraining the availability of planting material. Thus, the main objective of this work is to test the effect of humic substances (HS) on saffron vegetative propagation. The main results of trials indicate that HS improves the saffron plant's growth and development, and the intensity of response depends on the concentration used and the mode of application. In fact, the temporary treatment of corms with HS (50 and 100 ppm) improved plant and daughter corms growth but did not affect the number of shoots and corms

    Plastic and Reconstructive Surgery Advance Online Article

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    Background: The aim of this study was to evaluate the efficacy, safety profile, and complications associated with mandibular distraction osteogenesis performed in infants weighing less than 4 kg with Robin sequence. Methods: An 11-year retrospective review of all infants (younger than 6 months) with mandibular distraction osteogenesis–treated Robin sequence was performed. Patients weighing less than 4 kg (experimental) and 4 kg or more (control) who underwent mandibular distraction osteogenesis were compared. Demographics, medical comorbidities, improvement in apnea/hypopnea index, need for tracheostomy, repeated distraction, and complications were evaluated. Results: One hundred twenty-one patients underwent mandibular distraction osteogenesis. Eighty-one patients weighed less than 4 kg and 40 weighed 4 kg or more. The mean follow-up was 2.8 years in patients weighing less than 4 kg and 3.0 years in the control group. Mean age and weight at the time of distraction were 23 days and 3.1 kg, respectively, in the study group; and 2.7 years and 11 kg, respectively, in the control group. There was no significant difference in success of mandibular distraction osteogenesis to treat airway obstruction in the group weighing less than 4 kg compared with the control group (92.6 percent versus 88.9 percent; p = 0.49). The most common complication in each group was surgical-site infection (9.9 percent and 20.0 percent; p = 0.15). Overall complication rates were similar between the two groups (17.3 percent versus 25.0 percent; p = 0.34). The rates of repeated distraction were similar between the two groups (6.3 percent and 13.5 percent; p = 0.28). Conclusions: Mandibular distraction osteogenesis is a safe and effective treatment modality for infants weighing less than 4 kg with severe airway obstruction. The efficacy, safety, and complication profiles are not significantly different from those of larger patients. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, III

    Optimization of the explant disinfection method and in vitro multiplication of saffron (Crocus sativus L.).

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    Saffron (Crocus sativus L.), renowned as the world’s most expensive spice extracted from its stigmas, is an autumn-flowering, sterile triploid geophyte species (2n=3x=24) belonging to the Iridaceae family. It is propagated vegetatively through the development of daughter corms from the mother corm. Low multiplication rates of daughter corms under natural conditions and many biotic and abiotic stresses reduce productivity, thereby restraining the availability of planting material. Thus, the main objective of this work is to improve the vegetative propagation of saffron through tissue culture. The results show that soaking of explants in 0.1% (w/v) mercury chloride (HgCl2) for 10 min is more effective for explant disinfection (95%), with a survival rate of over 85%. Whereas, for the initiation phase, the in vitro culture of whole corms on Murashige and Skoog (MS) medium supplemented with 0.5 mg /L of 1-naphthalene acetic acid (NAA) in combination with 3 mg/L of 6-benzylaminopurine (BAP) was more effective, resulting in a sprouting rate of 90% with a maximum of 5 sprouted buds per explant. As for the multiplication phase, the highest number of shoots (4 shoots/single shoot explant) was observed on MS medium supplemented with 8 mg/L of BAP in combination with 0.5 mg/L of NAA. The results of this study can serve as a starting point for establishing an efficient and reproducible in vitro regeneration system in order to increase the number of shoots per explant for proliferation and micro-corms formation phases by exploring other culture media with different PGR combinations

    Effet de la durée d’exploitation de la culture du safran, installée à différentes densités, sur la production et la multiplication des cormes «semences» dans la région de Taliouine

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    In Taliouine region, the expansion of saffron cultivation requires the availability of good quality corms as propagated material. It is essential to establish an on-farm multiplication scheme to optimize corms production. A multi-year experiment over 5 seasons was carried out to study saffron behavior, planted at different planting densities (35, 50 and 100 corms/m2) in comparison with the traditional planting method (150 corms/m2), in local conditions of Taliouine. The results showed that low planting densities (35 and 50 corms/m2) favored higher multiplication rates of replacement corm and the number harvested was significantly similar to high planting density and to the traditional method. Nevertheless, the latter methods have produced low-weight replacement corms because of the negative effect on their sizes. On the other hand, in the case of low densities, 65% and 75% of corms had a satisfactory size, ensuring good production of saffron spice. Finally, we conclude that production and multiplication of corms “seeds” is directly related to the choice of planting density and expected yield of stigmas and corms according to the age of this perennial crop. Keywords: Saffron, corm, planting density, multiplication, TaliouineDans la région de Taliouine, le projet d’extension des superficies de la culture du safran suscite la question de la disponibilité des cormes-semences de bonne qualité. Il est primordial de dresser un schéma de multiplication en plein champ et d’optimiser la production des cormes «semence». Une expérimentation pluriannuelle, sur 5 saisons, dont l’objectif est l’étude du comportement d’une safranière installée à différentes densités (35, 50 et 100 cormes/m2) en comparaison avec le mode traditionnel (semis en poquet à 150 cormes/m2), a été réalisé dans les conditions du terroir de Taliouine. Les résultats ont montré que les densités de plantation légères (35 et 50 cormes/m2) ont engendré des taux de multiplication supérieurs et un rendement en nombre de cormes récoltés significativement semblables au cas des hautes densités et de la méthode traditionnelle de semis. Néanmoins, ces derniers cas ont engendré une production de cormes de remplacement de faibles poids et un effet négatif sur leurs calibres. Dans le cas de faibles densités, 65% et 75% des cormes ont un diamètre commercial supérieur assurant une bonne production de safran épice. La production et la multiplication des cormes de safran est directement liée au choix de la densité et du rendement escompté. Mots clés: Safran, corme, densité de plantation, multiplication, Taliouin
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