SIMPLIFICATION OF FISKE-SUBBAROWS ASSAY FOR INORGANIC-PHOSPHATE

28448349

PURIFICATION OF SOLUBLE AMPHIBIAN LIVER MITOCHONDRIAL ATPASE

8314714

Variability and discontinuity of the pathognomonic systemic effects caused by Walker 256 tumor progression in rats

Cancer pathognomonic systemic effects (PSE) have high individual variability, For this reason present data were collected daily and synchronized considering four main points: inoculation day, onset of PSE, aggravation and death, The subclinical period free of PSE ranged between 15.7+/-2.2 days, the clinical period was less variable, 8.9+/-0.5 days, divided in a moderate and a grave phase of nearly the same length, PSE involved disturbances of fundamental homeostatic regulations: appetite, sodium, water, immune, etc, PSE triggering correlated highly with survival (r(2)=0.95, P<0.01), but poorly with primary tumor growth, and it was anticipated by metastases from 20.5+/-2.6 to 10.6+/-1.1 days (P<0.01), After multifocal simultaneous inoculations, PSE triggering was anticipated to 4.2+/-0.2 days (marked reduction of individual variability), in the presence of small total-tumor masses, absence of macroscopic metastases, and without changes in the following clinical period features, PSE triggering seems to be a major prognostic indicator probably related to multifocal tumor growth.81537037

The effect of dietary lipids on rat liver mitochondrial swelling

The swelling of liver mitochondria resulting from changes in the dietary fatty acid (FA) was investigated in rats fed two lipid diets far two or four months. Female Sprague-Dawley Fats Were fed two semi-synthetic and isocaloric diets. One diet (CO diet) contained 10% coconut fat (rich in saturated fatty acids, SFA) while the other (SO diet) contained 10% sunflower seed oil (rich in unsaturated fatty acids, UFA). The initial velocity (Vo) was used to determine the velocity of the spontaneous and phosphate- or calcium-induced swelling of rat liver mitochondria. The changes in the fatty acid composition of the mitochondrial membranes were expressed as the unsaturation index, as well as the total content of saturated and unsaturated fatty acids and their ratios. The liver mitochondrial phospholipid fatty acid composition was very similar in both diet groups, in spite of the differences in dietary lipid fatty acid content. Only the 16:0, 16:1 (omega-7) and 16:1 (omega-9) fatty acids of the liver mitochondrial phospholipids differed significantly during the experiment. In general, the diets and the length of treatment had no significant influence on the extent of swelling. However, for animals fed the SO diet, significant differences in the for Vo of the phosphate- and calcium-induced swelling was observed. This result probably reflects greater fluidity of the mitochondrial membrane due to the high content of the fatty acid residues which would produce a more flexible and less stable membrane system.39497598

THE EFFECT OF THE THYROIDECTOMY IN MALE-RATS FED 2 ANTAGONIST LIPID DIETS .2. THE FATTY-ACID CONTENT OF LIPIDS OF PLASMA AND MITOCHONDRIA OF LIVER AND BRAIN

31236737

THE EFFECT OF LIPID DIETS AND CIGARETTE-SMOKING ON THE LEVELS OF SERUM-LIPIDS IN YOUNG MEN

29458159