1,314 research outputs found

    The CCFM uPDF evolution uPDFevolv

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    uPDFevolv is an evolution code for TMD parton densities using the CCFM evolution equation. A description of the underlying theoretical model and technical realization is given together with a detailed program description, with emphasis on parameters the user may want to changeComment: Code and description on https://updfevolv.hepforge.org Version to be published in EPJ

    Hepatic Lymphomas Post Renal Transplantation May Signify Worse Disease Behavior: Analysis of Data from 26 International Studies

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    Introduction: Hepatic involvement by posttransplant lymphoproliferative disorders (PTLD) is an important but rarely investigated issue. In the current study, we aimed to pool data of cases of PTLD localization in liver (L-PTLD) among renal allograft recipients from different series to find new perspectives on the disease. Methods: We conducted a comprehensive search for the available data through PubMed and Google Scholar for reports of PTLD localization in the liver and surrounding lymph nodes in renal allograft recipients. Data of 232 cases from 26 international studies have been pooled and reanalyzed. Results: Patients with L-PTLD were significantly more likely to be of male gender (P=0.02). Death due to PTLD was higher in L-PTLD patients (P=0.06). Disseminated PTLD, based on our definition, was significantly more prevalent in L-PTLD than in none-liver-PTLD (NL-PTLD) (P<0.001); the same finding was noted with multi-organ involvement which was significantly higher in L-PTLD (P<0.001). L-PTLD was significantly more likely to complicate heart (P=0.03), bone marrow (P=0.002), spleen (P=0.01), and kidney allograft involvement (P=0.04). Conclusion We conclude that renal transplant patients exhibiting liver localization for PTLD should be carefully followed for multi-organ involvement. Most notably, bone marrow biopsy should be considered, and evaluations for renal allograft, heart and spleen localization for PTLD should be executed. Due to the unfavorable characters of liver localization by PTLD in renal recipients, we propose higher levels of evaluations and follow up for these patients. Prospective studies with larger patient populations are needed to confirm our results.Keywords: Kidney Transplantation; Liver Localization; Lymphoproliferative Disorder

    TMD parton densities and corresponding parton showers: the advantage of four- and five-flavour schemes

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    The calculations of Z+bbˉZ + b{\bar b} tagged jet production performed in the four- and five-flavour schemes allow for detailed comparison of the heavy flavour structure of collinear and transverse momentum dependent (TMD) parton distributions as well as for detailed investigations of heavy quarks radiated during the initial state parton shower cascade. We have determined the first set of collinear and TMD parton distributions in the four-flavour scheme with NLO DGLAP splitting functions within the Parton-Branching (PB) approach. The four- and five-flavour PB-TMD distributions were used to calculate Z+bbˉZ + b{\bar b} tagged jet production at LHC energies and very good agreement with measurements obtained at s=8,13\sqrt{s} = 8, 13 TeV by the CMS and ATLAS collaborations is observed. The different configurations of the hard process in the four- and five-flavour schemes allow for a detailed investigation of the performance of heavy flavor collinear and TMD parton distributions and the corresponding initial TMD parton shower, giving confidence in the evolution of the PB-TMD parton densities as well as in the PB-TMD parton shower

    Synthesis of novel azo compounds containing 5(4H)-oxazolone ring as potent tyrosinase inhibitors

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    Six new azo dyes containing of 5(4H)-oxazolone ring were prepared by diazotization of 4-aminohippuric acid and coupling with N,N-dimethylaniline, 1-naphthol and 2-naphthol and condensation with 4-fluoro benzaldehyde or 4-trifluoromethoxy benzaldehyde. The new compounds were fully characterized by spectroscopic techniques. All synthesized compounds exhibited high tyrosinase inhibitory behavior. The results of mushroom tyrosinase inhibition assays indicate that the 4-trifluoromethoxy derivatives have high degrees of inhibition and N,N-dimethylaniline derivatives are better for tyrosinase inhibition than 1-naphthol and 2-naphthol derivatives. All synthesized azo compounds (4a-4f) showed the most potent mushroom tyrosinase inhibition, comparable to that of Kojic acid and l-mimosine, as reference standard inhibitors. © 2013 Elsevier Ltd. All rights reserved

    Aflatoxin contamination in wheat flour samples from Golestan province, Northeast of Iran

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    Background: Due to the high toxicity of aflatoxin and its effects on public health, determination of aflatoxin level in Wheat flour samples in the Golestan province, north of Iran was investigated. To examine the effect of seasonal changes, summer and winter sampling was performed with standard sampling methods. Methods: A total of 200 flour samples were collected from 25 factories. HPLC method with immunoaffinity chromatography was used to measure aflatoxin types (G2, G1, B2 and B1). Statistical analysis was performed by the Pearson correlation test, One-way ANOVA and multivariate regression analysis. Results: Mean total aflatoxin levels of samples were 0.82 and 1.99 ng/g in summer and winter, respectively. Aflatoxin B1 levels were detected in 3.1%, 7.4% over permissible limits by worldwide regulations in samples collected in summer and winter, respectively. Aflatoxins in winter were higher than summer. The highest frequency of aflatoxin contamination in winter was B2 (98%) and in summer G1 (51%). The relationship between humidity and rate of aflatoxin B1 and total aflatoxin was significant in winter. Results of multivariate regression were showed the strongest relationship with humidity and aflatoxin level. Despite the contamination of flour samples, there was no contamination higher than the standard limit of Iran Standard Institute. But it was significantly higher than similar studies from other regions. Conclusions: Therefore, with regard to negative impacts of aflatoxin on health, aflatoxin contamination should be considered in future programs. Decrease of aflatoxin contamination may be made practical through reducing wheat storage duration and controlling humidity

    Determination of collinear and TMD photon densities using the Parton Branching method

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    We present the first determination of transverse momentum dependent (TMD) photon densities with the Parton Branching method. The photon distribution is generated perturbatively without intrinsic photon component. The input parameters for quarks and gluons are determined from fits to precision measurements of deep inelastic scattering cross sections at HERA. The TMD densities are used to predict the mass and transverse momentum spectra of very high mass lepton pairs from both Drell-Yan production and Photon-Initiated lepton processes at the LHC.Comment: 5 pages, 4 figure

    Space shuttle electromagnetic environment experiment. Phase A: Definition study

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    A program is discussed which develops a concept for measuring the electromagnetic environment on earth with equipment on board an orbiting space shuttle. Earlier work on spaceborne measuring experiments is reviewed, and emissions to be expected are estimated using, in part, previously gathered data. General relations among system parameters are presented, followed by a proposal on spatial and frequency scanning concepts. The methods proposed include a nadir looking measurement with small lateral scan and a circularly scanned measurement looking tangent to the earth's surface at the horizon. Antenna requirements are given, assuming frequency coverage from 400 MHz to 40 GHz. For the low frequency range, 400-1000 MHz, a processed, thinned array is proposed which will be more fully analyzed in the next phase of the program. Preliminary hardware and data processing requirements are presented

    Epidemiology of female reproductive cancers in Iran: Results of the gholestan population-based cancer registry

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    Background: Malignancies of the female reproductive tract are estimated to be the third most common group of cancers in women. Objectives: We here aimed to present their epidemiological features in Golestan provincelocated in Northeast of Iran. Materials and Methods: Data on primary female reproductive cancers diagnosed between 2004-2010 were obtained from Golestan Population-based Cancer Registry (GPCR). CanReg-4 and SPSS software were used for data entry and analysis. Age standardized incidence rates (ASR) (per 100,000 person-years) were calculated using the world standard population. Poisson regression analysis was used to compare incidence rates. P-values of less than 0.05 were considered as significant. Results: A total of 6,064 cancer cases were registered in Golestan females in the GPCR during 2004-2010, of which 652 cases (11%) were female reproductive cancers. Cancers of the ovary (ASR=6.03) and cervix (ASR=4.97) were the most common. We found significant higher rates in females living in cities than in villages. Our results showed a rapid increase in age specific incidence rates of female reproductive cancers at the age of 30 years. Conclusions: We found significant higher rates of female reproductive cancers among residents of cities than villages. Differences in the prevalence of risk factors including reproductive behavior between the two populations may partly explain such diversity. Our results also showed a rapid increase in incidence rates of these cancers in young age females. Further studies are warranted to determine risk factors of female reproductive cancers in our population
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