26 research outputs found

    3-D Measurement of a Human Body

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    This paper describes a system which enables a fast 3-dimensional profile measurement of a human body using a slit-ray projection method. One distinctive feature of this system is that a real-time video processor is employed in order to reduce the amount of image data to be processed without eliminating essential information and enable a fast measurement of the human body. Experimental results show that a calibrating method presented for the TV cameras and the slit-ray projector is convenient and enables sufficient accurate measurements

    Activation of Sympathetic Signaling in Macrophages Blocks Systemic Inflammation and Protects against Renal Ischemia-Reperfusion Injury

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    Background: The sympathetic nervous system regulates immune cell dynamics. However, the detailed role of sympathetic signaling in inflammatory diseases is still unclear because it varies according to the disease situation and responsible cell types. This study focused on identifying the functions of sympathetic signaling in macrophages in LPS-induced sepsis and renal ischemia-reperfusion injury (IRI).Methods: We performed RNA sequencing of mouse macrophage cell lines to identify the critical gene that mediates the anti-inflammatory effect of β2-adrenergic receptor (Adrb2) signaling. We also examined the effects of salbutamol (a selective Adrb2 agonist) in LPS-induced systemic inflammation and renal IRI. Macrophage-specific Adrb2 conditional knockout (cKO) mice and the adoptive transfer of salbutamol-treated macrophages were used to assess the involvement of macrophage Adrb2 signaling.Results: In vitro, activation of Adrb2 signaling in macrophages induced the expression of T cell Ig and mucin domain 3 (Tim3), which contributes to anti-inflammatory phenotypic alterations. In vivo, salbutamol administration blocked LPS-induced systemic inflammation and protected against renal IRI; this protection was mitigated in macrophage-specific Adrb2 cKO mice. The adoptive transfer of salbutamol-treated macrophages also protected against renal IRI. Single-cell RNA sequencing revealed that this protection was associated with the accumulation of Tim3-expressing macrophages in the renal tissue.Conclusions: The activation of Adrb2 signaling in macrophages induces anti-inflammatory phenotypic alterations partially via the induction of Tim3 expression, which blocks LPS-induced systemic inflammation and protects against renal IRI

    Fast Three-Dimensional Measurement Technique Using a Reference Table : Measurement of a Human Head

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    This paper describes a system which enables fast 3-dimensional measurementof a human head by means of a slit ray projection method. The system developed here consists of a laser slit ray projector, two CCD TV cameras, a real-time video signal processor and a 32-bit computer. Due to the employment of this real-time video signal processor and a fast data-processing technique using a reference table, a 3-dimensional measurement of the human head can be Accomplished in 4.3 seconds, and all the image data are converted to 3-dimensional data in one second. Experimental data reveal the applicability of our system

    Modeling Tactical Changes of Formation in Association Football as a Non-Zero-Sum Game

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    In football leagues, a won match produces three points (all for the winner) whereas a drawn match produces only two (one for each team). Here, the total resource from the viewpoint of league points is not constant and the gain of the match for both teams changes depending on the result of the match. To cater for this situation, we propose a formulation for modelling tactical changes of formation in an association football match as a non-zero-sum game using game theory. In this paper, we focus on two well-known teams in the J. League and analyse their offensive and defensive strengths based on their formation, i.e., a combination of the number of each type of outfield player on the pitch. Using these estimated offensive and defensive strengths, we develop the mathematical formulation for analyzing tactical changes of these teams' formations from the viewpoint to increase their expected number of league points gained in a match, and quantitatively demonstrate not only the effect of the introduction of the league point system on the tactical change, but also the effect of cooperation between managers which could make both teams benefit in terms of the expected number of league points gained in a match.
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