1,160 research outputs found

    Limiting flows of a viscous fluid with stationary separation zones with Re approaching infinity

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    The limiting flows of a viscous noncondensable fluid, which are approached by flows with stationary separation zones behind planar symmetrical bodies, with an unlimited increase in the Reynolds number are studied. Quantitative results are obtained in the case of a circulation flow inside of a separation zone

    NF-{kappa}B-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses

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    Activation of mammalian innate and acquired immune responses must be tightly regulated by elaborate mechanisms to control their onset and termination. MicroRNAs have been implicated as negative regulators controlling diverse biological processes at the level of posttranscriptional repression. Expression profiling of 200 microRNAs in human monocytes revealed that several of them (miR-146a/b, miR-132, and miR-155) are endotoxin-responsive genes. Analysis of miR-146a and miR-146b gene expression unveiled a pattern of induction in response to a variety of microbial components and proinflammatory cytokines. By means of promoter analysis, miR-146a was found to be a NF-{kappa}B-dependent gene. Importantly, miR-146a/b were predicted to base-pair with sequences in the 3' UTRs of the TNF receptor-associated factor 6 and IL-1 receptor-associated kinase 1 genes, and we found that these UTRs inhibit expression of a linked reporter gene. These genes encode two key adapter molecules downstream of Toll-like and cytokine receptors. Thus, we propose a role for miR-146 in control of Toll-like receptor and cytokine signaling through a negative feedback regulation loop involving down-regulation of IL-1 receptor-associated kinase 1 and TNF receptor-associated factor 6 protein levels

    Contribution to the theory of stationary separation areas

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    An attempt is made to determine the region of existence of possible steady flows with a closed separation area in a range of Reynolds numbers such that flow in the viscous mixing area can be described by the Prandtl's equations. The boundary conditions for the flow in the separation region are selected so as to simplify the flow pattern in this region, making it possible to use the methods of hydrodynamic analysis. A rule for determining stable steady flows with separation areas is formulated which is well suited for analyzing laminar flows and can be applied to turbulent flows in some areas

    CHILDREN‘S LEARNING OUTCOMES AND DEVELOPMENT OF PHYSICAL EXPERIENCE IN GRAPHICS

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    This article deals with the development of graphic design skills, graphic design and space imagery in engineering graphics and drawing geometr

    FDI and Long-term Economic Growth in Russia

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    In this paper we consider relationship between foreign direct investment (as one of the mechanisms of technological development) and long-term economic growth. In the beginning we discuss the role of FDI in the increase of total factor productivity from the viewpoint of endogenous growth theory. We then turn to the comparative analysis of FDI inflow to Russia and other countries broken down by economic industries. We find that Russian industries capable of increasing TFP and positively impacting the long-term economic growth are significantly underinvested relative to other countries. Since, in our opinion, pre-existing sources of Russia’s economic growth are almost completely exhausted, we suggest several economic policy measures aimed at attracting FDI in Russia and improve the absorptive capacity of the country

    FDI and Long-term Economic Growth in Russia

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    In this paper we consider relationship between foreign direct investment (as one of the mechanisms of technological development) and long-term economic growth. In the beginning we discuss the role of FDI in the increase of total factor productivity from the viewpoint of endogenous growth theory. We then turn to the comparative analysis of FDI inflow to Russia and other countries broken down by economic industries. We find that Russian industries capable of increasing TFP and positively impacting the long-term economic growth are significantly underinvested relative to other countries. Since, in our opinion, pre-existing sources of Russia’s economic growth are almost completely exhausted, we suggest several economic policy measures aimed at attracting FDI in Russia and improve the absorptive capacity of the country

    Quantifying the Value of Preferential Trade in Russia and CIS

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    In this paper, we assess the value of Russia’s preferential imports from all trade partners and CIS countries in particular. Total value of preferential imports in Russia (both duty free imports as well as imports subject to the discounted MFN duty under GSP) is equal to ca 12% (37.8 USD bln.) of the total imports, of which ca 7.4% accounted for imports of Russia from CIS countries. We should note that ca 2.5% of preferential imports of Russia under GSP treatment was not imported duty free, but was subject to a 25% discount to MFN duty
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