STOMATOLOGICAL/DENTAL FEATURES OF VITAMIN D RESISTANT AND VITAMIN D DEPENDENT RICKETS

The aim of the study is an investigation of stomatological/dental characteristics at vitamin D resistant and vitamin D dependent rickets. Materials and methods: The study was based on the results obtained after investigation of 13 patients 0-18 of ages with D vitamin resistant rickets (I group) and 68 patients with D vitamin-dependent rickets (II group) and 61 children of control group. Physical development, dental status and biochemical features of the mentioned children have been studied. Methods of the study: anamnesis, clinical examination, X-ray examination, blood and urine biochemical analysis. Quantity data were compared according to - t (student) criteria and qualitative data – according to - F (fisher) criteria. Clinical data were processed with statistical programs package SPSS 22. Results: The incidence rates of insufficient physical development (physical retardation), body constitutional disorder, jaw shape, occlusion and teeth constitutional anomalies as well as delayed teeth eruption are significantly higher at vitamin D resistant rickets in comparison with vitamin D-dependent rickets and control group. The incidence rate of enamel hypoplasia in group of vitamin D resistant rickets is 0.69, vitamin D dependent group - 0.07(p>0.000) and control group – 0,03( p>0.000), respectively, the rate of periapical abscesses with canal orifice – in group of vitamin D-resistant rickets equals to 0.31, vitamin D-dependent group – 0.06(p=0.054), and control group - 0.10(p=0.0457), respectively, which is significantly higher in comparison with the dependent rickets and control groups. Among the children with vitamin D resistant rickets, average caries intensity (DMF) index and average PMA index p>0.05 are reliably higher in comparison with vitamin D dependent rickets. Tubular phosphate reabsorption reveals positive correlation with DMF index – r =0.57, p = 0.0380; PMA index - r=0.84, p=0.0003; reduction of tubular phosphate reabsorption correlates with caries r=0.6770, p=0.0110; pulpitis r =0.6770, p =0.0110; periodontitis r=0.6770, p=0.0110. Conclusion: At vitamin D resistant rickets the dental anomalies, being in correlation with metabolic disorder, occur

STOMATOLOGICAL/DENTAL FEATURES OF VITAMIN D RESISTANT AND VITAMIN D DEPENDENT RICKETS

The aim of the study is an investigation of stomatological/dental characteristics at vitamin D resistant and vitamin D dependent rickets. Materials and methods: The study was based on the results obtained after investigation of 13 patients 0-18 of ages with D vitamin resistant rickets (I group) and 68 patients with D vitamin-dependent rickets (II group) and 61 children of control group. Physical development, dental status and biochemical features of the mentioned children have been studied. Methods of the study: anamnesis, clinical examination, X-ray examination, blood and urine biochemical analysis. Quantity data were compared according to - t (student) criteria and qualitative data – according to - F (fisher) criteria. Clinical data were processed with statistical programs package SPSS 22. Results: The incidence rates of insufficient physical development (physical retardation), body constitutional disorder, jaw shape, occlusion and teeth constitutional anomalies as well as delayed teeth eruption are significantly higher at vitamin D resistant rickets in comparison with vitamin D-dependent rickets and control group. The incidence rate of enamel hypoplasia in group of vitamin D resistant rickets is 0.69, vitamin D dependent group - 0.07(p>0.000) and control group – 0,03( p>0.000), respectively, the rate of periapical abscesses with canal orifice – in group of vitamin D-resistant rickets equals to 0.31, vitamin D-dependent group – 0.06(p=0.054), and control group - 0.10(p=0.0457), respectively, which is significantly higher in comparison with the dependent rickets and control groups. Among the children with vitamin D resistant rickets, average caries intensity (DMF) index and average PMA index p>0.05 are reliably higher in comparison with vitamin D dependent rickets. Tubular phosphate reabsorption reveals positive correlation with DMF index – r =0.57, p = 0.0380; PMA index - r=0.84, p=0.0003; reduction of tubular phosphate reabsorption correlates with caries r=0.6770, p=0.0110; pulpitis r =0.6770, p =0.0110; periodontitis r=0.6770, p=0.0110. Conclusion: At vitamin D resistant rickets the dental anomalies, being in correlation with metabolic disorder, occur

The Correlation of Collateral Circulation and Age during Acute Ischemic Heart Disease

Backgroundː Coronary collaterals (CC) are alternative sources of blood supply to myocardium jeopardized by Ischemia. Aim: To investigate the dependence and influence of collateral circulation on age during acute ischemic heart disease. Methods: Analysis shows that 673 patients were studied from the SamgoriMedi Clinic (Tbilisi, Georgia) aged 27– 94 years (64.7+11.48) with acute coronary syndromes. Basic medical data such as sex, age, cardiovascular risk factors, angina pectoris, revascularization history, echocardiography, and laboratory data were obtained from the patient’s medical records. CC vessels were graded according to the Rentrop grading system of 0 to 3. Resultsː The development index of collateral circulations visibly increases with age. Average age increases accordingly as follows: rentrop 0 - 62.85+12.01, rentrop 1 - 64.90+10.79, rentrop 2 - 66.84+10.49, and rentrop 3 - 69.04+9.68 (p<0.0001). There is positive significant correlation between the development of collateral circulation and age groups r=0.170**, p<0.001. The cases of female sex, hypertension, acute MI without ST elevation, CABG frequency (also EF% - 35-45%, <35%), and multiple vessel coronary lesion are noticed to increase with age, while the male sex and EF (ejection fraction) >45% cases decreases with age. Conclusion Collateral circulation shows significantly positive correlation with age and female sex. However, it should be mentioned that in elderly patients with a high ejection fraction and normal diastolic function, the development of collateral vessels is low

Evaluation of the Clinical and Immunological Parameters During Treatment Chronic Periodontitis by Camelyn Mouthwash

The purpose of study is Evaluation of Clinical and Immunological effects of using Camelyn in Periodontology. Materials and methods: We have studied clinical and immunological features of 20 patients with periodontitis between ages 20 and 60 (these patients were from the dental clinic Mitra). CPI index has been studied dynamically — before treatment, after treatment, 6 months and 1 year later. Treatment included scaling and root planning. During these 2 weeks we have used 10 ml of Camelyn 25 percent solution for rinsing. We applied it for 2 minutes. We checked cellular and humoral immunity in peripheral blood stem. Lysozyme activation was determined. Results: After treatment, the median CPI index was significantly reduced. After 6 months and a year of treatment it was insignificantly increased, but in comparison with the initial CPI it was remained significantly less.Before starting treatment Interferon and the phagocytic system was significantly lowered, also amount of TLymphocytes, but the amount of T suppressors was increased; After the treatment mentioned above the parameters were significantly increased, although in comparison with the standard it still was low. After the treatment the amount of T- suppressors was significantly decreased.Saliva significantly showed a reduction of the amount of lysozyme and sIgA Before treatment IgG was significantly lower and IgM higher. After the treatment all kinds of Immunoglobulins were almost the same; Conclusion: Including Camelyn in traditional treatment of periodontitis promotes immune response activation and it has a positive influence on a clinical picture —it improves periodontitis clinical features and significantly reduces CPI index

Risk Factors for Spontaneous Abortion in Georgian Population

Background: Spontaneous abortion is a difficult problem for reproduction. This leads to the importance of studying risk factors. Since risk factors depend on demographic, ethnic, and environmental conditions of the population. The aim of our explore is to study the risk factors for spontaneous abortions and risk assessment among the population of Georgia. Methods: We retrospectively studied the clinical and laboratory features of 111 patients with identified spontaneous abortions who were treated at the Gudushauri clinic in 2015-2017. The control was carried out in the same period during the outpatient department of the Gudushauri clinic, 103 pregnant women who gave birth to live neonates. Research methods: history, clinical, clinical laboratory, immunological, morphological, bacteriological, ultrasound. The study of the following factors: age, education, family conditions, living conditions, bad habits, activities, working conditions, hereditary factors, accommodation, extragenital diseases, diet, physical activity, sleep hygiene, gynecological history, uterine deformities, medication during pregnancy, the results of a previous pregnancy, pregnancy complications, infections. Results: The risk ofspontaneous abortion increases: Daily travel to long distance OR=4.34(95% CI:1.45-3.03); Stress - OR=6.36(95% CI:2.43-16.66); intermittent sleep - OR=5.72(95%CI:2.15-15.19); Menstrual disorders OR=9.91(95%CI:2.01- 48.94); hypertension OR=15.26(95% CI:1.03-27.24); anemia- OR=4.14(95% I:1.78-9.62); Flu during pregnancy - OR=6.24(95% CI:1.63-23.90); leukocytosis - OR=1.32(95%CI:1.12-1.55) and decrease the placenta location in the base- OR=0.09(95%CI:0.02-0.47). Conclusion: Daily travel to long distance, flu, anemia, leukocytosis, stress, intermittent sleep during pregnancy, menstrual disorders, hypertension are the independent risk factors of spontaneous abortion in Georgian Population, relative chance of spontaneous abortion reduce: placenta at the base. The risk of spontaneous abortion in Georgian population is not determined by relationship status, bad habits and educational factors

Complications and In-Hospital Mortality After On- Pump Vs Off-Pump Coronary Artery Bypass Grafting

Off-pump surgery has involved into the most frequently adopted alternative technique to conventional on-pump coronary artery bypass grafting (CABG) in the treatment of patients with coronary artery disease. Our aim was to compare data analyses of complications and in-hospital mortality after on-pump vs off-pump CABG. Materials and methods: Retrospective data analyses research is based on 402 patients, ranging in 37-75 years of age. Operations CABG were performed in 2009- 2012, at the West Georgian Interventional Medicine National Center Hospital, Kutaisi; Aleksandre Aladashvili Clinic, Tbilisi; and L.T.D. Lancet, Tbilisi. 253 cases were performed off pump and 149 cases were performed on pump. Groups were diversified by the F Fischer’s criteria. Odds ratio (OR) was made using regression analysis. Statistical analysis was made using SPSS 22 program. Results: While on pump during surgery, intraoperative shock occurred in 8(5.37%) cases, Thrombosis – 3(2.01%); Dissection – 3(2.01%), Stroke – 1(0.67%) and Myocardial Infarction – 1(0.67%). These complications were not detected during off pump CABG. Frequency of in-hospital mortality after off pump and on pump CABG are respectively 7(2.77%) and 15(10.07%) - p<0.0018. Totallyperi operative  complications were during off pump CABG – 35(13.83%) and on pump CABG – 41(27.51%)(p<0.0007). In the cases of on pump surgery, odds ratio of complications that arise: bleeding OR=4.48(95CI;1.38-14.54); atrial fibrillation – OR=6.64(95%CI:1.82-24.21); pulmonary complications - OR=2.24(95%CI:1.19-4.21), renal insufficiency - OR=8.75(95%CI:1.01- 75.63); in-hospital mortality – OR=2.365(95%CI:1.425-3.924). Conclusion: Off pump CABG seems to significantly reduce postoperative renal failure, bleeding, atrial fibrillation, and respiratory complications, while perioperative myocardial infarction rates remain significantly unchanged. Considering in-hospital mortality and perioperative complications, off pump CABG has much better results

THE IMPACT OF COMPUTER AND INFORMATION COMMUNICATION TECHNOLOGY LITERACY ON THE ACADEMIC ACHIEVEMENT OF MEDICAL AND DENTAL STUDENTS AT SHIRAZ UNIVERSITY OF MEDICAL SCIENCES

The internet, since its advent, has been well embraced and broadly used by students, faculty members and researchers as an information source, and as a tool for collaboration, learning and also a tool for the dissemination of research results. As such the internet is assumed to have a great effect on both the quality and quantity of research and education worldwide. In this regard, many studies have been conducted to know more about the applications and outcomes of the internet in educational fields. This article, in line with previous studies, was an attempt to investigate the impact of students’ computer and information communication technology (ICT) literacy on their academic achievement. According to the results, the Pearson correlation coefficient between students computer grades as a measure of their ICT skill and their grade point averages was (R=0.367, P<=0.01) which shows a positive and significant relationship between these two variables. Adopting a self-evaluation procedure, the students scored themselves low to average, regarding the application of numerous information services available to them on the campus. They additionally self-evaluated their skills in using Microsoft Office products as good. Their knowledge and skill with regard to internet and email services was ranked as very good. The students spent nearly 3 hours a day on different internet activities as follows: internet search (60 minutes), social networks (45 minutes) and electronic mails (30 minutes)