22 research outputs found
A primordial, mathematical, logical and computable, demonstration (proof) of the family of conjectures known as Goldbach´s
Get PDFlicencia de Creative Commons Reconocimiento-NoComercial-SinObraDerivada 4.0 Internacional.In
this
document,
by
means
of
a
novel
system
model
and
first
order
topological,
algebraic
and
geometrical
free-‐context
formal
language
(NT-‐FS&L),
first,
we
describe
a
new
signature
for
a
set
of
the
natural
numbers
that
is
rooted
in
an
intensional
inductive
de-‐embedding
process
of
both,
the
tensorial
identities
of
the
known
as
“natural
numbers”,
and
the
abstract
framework
of
theirs
locus-‐positional
based
symbolic
representations.
Additionally,
we
describe
that
NT-‐FS&L
is
able
to:
i.-‐
Embed
the
De
Morgan´s
Laws
and
the
FOL-‐Peano´s
Arithmetic
Axiomatic.
ii.-‐
Provide
new
points
of
view
and
perspectives
about
the
succession,
precede
and
addition
operations
and
of
their
abstract,
topological,
algebraic,
analytic
geometrical,
computational
and
cognitive,
formal
representations.
Second,
by
means
of
the
inductive
apparatus
of
NT-‐FS&L,
we
proof
that
the
family
of
conjectures
known
as
Glodbach’s
holds
entailment
and
truth
when
the
reasoning
starts
from
the
consistent
and
finitary
axiomatic
system
herein
describedWe
wish
to
thank
the
Organic
Chemistry
Institute
of
the
Spanish
National
Research
Council
(IQOG/CSIC)
for
its
operative
and
technical
support
to
the
Pedro
Noheda
Research
Group
(PNRG).
We
also
thank
the
Institute
for
Physical
and
Information
Technologies
(ITETI/CSIC)
of
the
Spanish
National
Research
Council
for
their
hospitality.
We
also
thank
for
their
long
years
of
dedicated
and
kind
support
Dr.
Juan
Martínez
Armesto
(VATC/CSIC),
Belén
Cabrero
Suárez
(IQOG/CSIC,
Administration),
Mar
Caso
Neira
(IQOG/CENQUIOR/CSIC,
Library)
and
David
Herrero
Ruíz
(PNRG/IQOG/CSIC).
We
wish
to
thank
to
Bernabé-‐Pajares´s
brothers
(Dr.
Manuel
Bernabé-‐Pajares,
IQOG/CSIC
Structural
Chemistry
&
Biochemistry;
Magnetic
Nuclear
Resonance
and
Dr.
Alberto
Bernabé
Pajares
(Greek
Philology
and
Indo-‐European
Linguistics/UCM),
for
their
kind
attention
during
numerous
and
kind
discussions
about
space,
time,
imaging
and
representation
of
knowledge,
language,
transcription
mistakes,
myths
and
humans
always
holding
us
familiar
illusion
and
passion
for
knowledge
and
intellectual
progress.
We
wish
to
thank
Dr.
Carlos
Cativiela
Marín
(ISQCH/UNIZAR)
for
his
encouragement
and
for
kind
listening
and
attention.
We
wish
to
thank
Miguel
Lorca
Melton
for
his
encouragement
and
professional
point
of
view
as
Patent
Attorney.
Last
but
not
least,
our
gratitude
to
Nati,
María
and
Jaime
for
the
time
borrowed
from
a
loving
husband
and
father.
Finally,
we
apologize
to
many
who
have
not
been
mentioned
today,
but
to
whom
we
are
grateful.
Finally,
let
us
point
out
that
we
specially
apologize
to
many
who
have
been
mentioned
herein
for
any
possible
misunderstanding
regarding
the
sense
and
intension
of
their
philosophic,
scientific
and/or
technical
hard
work
and
milestone
ideas;
we
hope
that
at
least
Goldbach,
Euler
and
Feymann
do
not
belong
to
this
last
human´s
collectivity.Peer reviewe
The Interaction of Biological and Environmental Factors in Predicting Educational Attainment: The Role of Early Pubertal Development Among Emerging Adult Women in Rural and Urban Settings
Get PDFThe inventlon provides highly functionahsed spiro-fused azetidinones having a cyclohexane moiety with the desired
number of protected or unprotected hydroxyl groups or carbonated structures, which are introduced with high stereo
and regioselectivity, as well as processes for their obtention.Peer reviewedA1 Solicitud de patente con informe sobre el estado de la técnic
A Study of Organization Communication towards Effective Decision Making -Roles of "Information" and Governance on IT Projects-
Get PDFLa invención proporciona intermedios útiles para la síntesis
de TTX y análogos de la misma, así como procedimientos
para la síntesis de los mismos. Los compuestos
de la invención proporcionan acceso de forma flexible a
distintos análogos de TTX.Peer reviewedConsejo Superior de Investigaciones CientíficasB1 Patente sin examen previ
Regioselective functionalisation and protection of spirolactams
Get PDFThe invention provides highly functionalised spiro-fused lac
tams of en formula (I) having a cyclohexane moiety With the
desired number of protected or un-protected functional
groups or carbonated structures, Which are introduced With
high stereo and regioselectivity, as Well as processes for their
obtention. These compounds are useful for the synthesis of
abroad range of bioactive molecules, such as condoritols and
aminoinositols and their analogues.Peer reviewedLaboratorios del Dr. Esteve S.A.A1 Solicitud de patente con informe sobre el estado de la técnic
Dimethano-[1,3]dioxocino[6,5-D]pyrimidine-spiro derivatives of tetrodotoxin, process for their synthesis and uses thereof in the treatment of pain
Get PDFThe present invention relates to a method for
the preparation of derivatives of dimethano-[1,3]dioxocino
[6,5-d]pyrimidine-spiro derivatives of formula II, III and
IV. The present invention also relates to the derivatives
of fonnula II, III and IV obtained through the method described,
to pharmaceutical compositions comprising the
same and to their use as a medicament.Peer reviewedWex Pharmaceuticals Inc.A1 Solicitud de patente con informe sobre el estado de la técnic
Dimethano-[1,3]dioxocino[6,5-D]pyrimidine-spiro derivatives of tetrodotoxin, process for their synthesis and uses thereof
No full textThe present invention relates to a method for the preparation of derivatives of dimethano-[1,3]dioxocino[6,5-d]pyrimidine-spiro derivatives of formula II, III and IV. The present invention also relates to the derivatives of formula II, III and IV obtained through the method described, to pharmaceutical compositions comprising the same and to their use as a medicament.Peer reviewedWex Pharmaceuticals Inc.A2 Solicitud de patente sin informe sobre el estado de la técnic
Hidroxilación, funcionalización y protección regioselectivas de espirolactamas
Get PDFLa invención proporciona azetidinonas espirocondensadas
sumamente funcionalizadas que tienen un resto ciclohexano
con el número deseado de grupos hidroxilo protegidos
o sin proteger, que se introducen con alta estereo
y regioselectividad, así como procedimientos para su obtención.Peer reviewedLaboratorios del Dr. Esteve S.A.A1 Solicitud de patente con informe sobre el estado de la técnic
Synthesis of ttx intermediates
Get PDFThe present invention relates to the synthesis of intermediates which are useful in TTX synthesis and to the preparation thereof.Peer reviewedA1 Solicitud de patente con informe sobre el estado de la técnic
Regioselective functionalisation and protection of spirolactams
No full textThe invention provides highly functionalised spiro-fused lactams of
formula (1) having a cyclohexane moiety with the desired number of protected or unprotected
functional groups or carbonated structures, which are introduced with high
stereo and regioselectivity, as well as processes for their obtention. These compounds
are useful for the synthesis of a broad range ofbioactive molecules, such as condoritols
and aminoinositols and their analogues.Peer reviewedLaboratorios del Dr. Esteve S.A.A1 Solicitud de patente con informe sobre el estado de la técnic
Spirolactames et leur synthese
No full textNew spirolactams of formula (1) having a cycloexadienone moiety which are highly stable due to pi interactions between the W group and the dienone moiety. They are useful as UV absorbers and as intermediates for the synthesis of active biomolecules.Peer reviewedLaboratorios del Dr. Esteve S.A.A1 Solicitud de patente con informe sobre el estado de la técnic
