Factors affecting visual acuity after accelerated crosslinking in patients with progressive keratoconus

ABSTRACT Purpose: The present study aimed to report the outcomes of patients with progressive keratoconus who were treated via accelerated crosslinking (CXL) 6 months earlier and to determine the factors that promoted improved visual acuity after treatment. Methods: This retrospective study included 35 eyes of 34 patients with progressive keratoconus who underwent CXL. Topographical measurements were obtained preoperatively and in the first, third, and sixth months postoperatively using a rotating Scheimpflug camera. The uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), flat keratometry (K) value (K1), steep K value (K2), average K value (avgK), topographic cylindrical value (Cyl), apical keratoscopy front (AKf), apical keratoscopy back (AKb), symmetry index front (SIf), symmetry index back (SIb), and thinnest point of the cornea (ThkMin) were recorded. Results: At the 6-month follow-up, the mean UCVA and BCVA values were improved, and the K values remained stable. Statistically significant decreases in AKf (p=0.04) and the thinnest point of the cornea (p=0.001) and a statistically significant increase in AKb (p=0.01) were observed. A correlation analysis revealed that the preoperative BCVA, UCVA, K1, K2, avgK, AKf, and AKb values significantly affected visual acuity at the 6-month follow-up. Conclusions: Accelerated CXL is an effective treatment for the prevention or even reversal of keratoconus progression. The preoperative K values and apexes of the anterior and posterior cornea were found to affect visual acuity at 6 months after accelerated CXL. Both AKb steepening and AKf flattening appear to be important factors in the stabilization of keratometric values and improvement of visual outcomes

Glokomu ilaçla regüle olmayan kataraktlı olgularda kombine fakotrabekülektomi

Mustafa Özsütçü, Cemil Yılmazlı, Muhittin Taşkapılı, K. Turgay Özbilen, Glokomu ilaçla regüle olmayan kataraktlı olgularda kombine fakotrabekülektomi, TOD 41. Ulusal Oftalmoloji Kongresi, 30.10.2007 POS-1-GL-08

The effects of hemodialysis on tear osmolarity

WOS: 000365249700001PubMed ID: 26640702Aim. To determine the effects of hemodialysis (HD) on tear osmolarity and to define the blood biochemical tests correlating with tear osmolarity among patients with end stage renal disease (ESRD). Material-Method. Tear osmolarity of ESRD patients before and after the hemodialysis program was determined as well as the blood biochemical data including glucose, sodium, potassium, calcium, urea, and creatinine levels. Results. Totally 43 eyes of 43 patients (20 females and 23 males) with a mean age of 53.98 +/- 18.06 years were included in the study. Tear osmolarity of patients was statistically significantly decreased after hemodialysis (314.06 +/- 17.77 versus 301.88 +/- 15.22mOsm/L, p = 0.0001). In correlation analysis, pre-HD tear osmolarity was negatively correlated with pre-HD blood creatinine level (r = -0.366, p = 0.016). Post-HD tear osmolarity was statistically significantly correlated with the post-HD glucose levels (r = 0.305 p = 0.047). Tear osmolarity alteration by HD was negatively correlated with creatinine alteration, body weight alteration, and ultrafiltration (r = -0.426, p = 0.004; r = -0.365, p = 0.016; and r = -0.320, p = 0.036, resp.). There was no correlation between tear osmolarity and Kt/V and URR values. Conclusion. HD effectively decreases tear osmolarity to normal values and corrects the volume and composition of the ocular fluid transiently. Tear osmolarity alteration induced by HD is correlated with body weight changes, creatinine alterations, and ultrafiltration

Konvansiyonel dekolman cerrahisinde çevresel skleral çökertme sonrası gözlenen refraksiyon değişiklikleri

Özbilen KT, Özcan Z, Taşkapılı M, Kocabora MS, Çekiç O. Konvansiyonel dekolman cerrahisinde çevresel skleral çökertme sonrası gözlenen refraksiyon değişiklikleri ( Poster) TOD 43. Ulusal Kongresi.11-15 Kasım 200

Tek Gözlü bir hastada künt travma sonrası 180 derecelik skleral rüptür

Derya Kulaç, K.Turgay Özbilen, Muhittin Taşkapılı, M.Selim Kocabora, Korhan Fazıl-Tek Gözlü bir hastada künt travma sonrası 180 derecelik skleral rüptür. (Poster) TOD 41. Ulusal kongresi 30 Ekim -2 Kasım 200

İki günde bilateral körlük yapan temporal arterit

Kemal Turgay Özbilen, Muhittin Taşkapılı, Gökhan Gülkılık, Caner Karakaya, Mustafa Özsütçü, Erdem Telli, İki günde bilateral körlük yapan temporal arterit, TOD 40. Ulusal Oftalmoloji Kongresi 30.10.2006 [P-NO-04

Efficacy of Intravitreal Bevacizumab in Treatment of Proliferative Type 2 Idiopathic Juxtafoveal Telangiectasia

Objectives: To evaluate the effectiveness of intravitreal bevacizumab (IVB) in patients with subretinal neovascularization secondary to type 2 juxtafoveal telangiectasia. Materials and Methods: Ten eyes of 10 patients were included in this retrospective study. All cases were treated with IVB (1.25 mg bevacizumab). Visual acuity and slit-lamp anterior and posterior segment examinations were performed at each visit. Central macular thickness (CMT) and intraretinal/subretinal fluid were evaluated via spectral domain optical coherence tomography (OCT). Loss of a line in visual acuity chart and presence of fluid on OCT were defined as criteria for repeated treatment. Results: The mean age of patients was 66.0±7.0 years (56-75). The mean follow-up time was 54.7±16.0 month (24-72). The mean BCVA was 0.62±0.35 (0.00-1.00) logMAR at baseline and 0.54±0.35 (0.00-1.00) logMAR at final exam (p=0.03). The mean CMT was 251±25.4 µm at baseline and 239±39.3 µm at final exam (p=0.01). Patients received an average of 1.7±1.0 IVB injections during follow-up. At baseline, all cases had intraretinal/subretinal fluid. There was no fluid at final examination of all cases. Conclusion: IVB treatment may be effective in the treatment of subretinal neovascularization secondary to type 2 juxtafoveal telangiectasia

Diyabetik makula ödeminde intravitreal Bevasizumab ve Grid Fotokoagülasyon karşılaştırılması

Kandemir N, Karadeniz D, Fazıl K, Özbilen T, Kocabora MS, Taşkapılı M, Çekiç O.Diyabetik makula ödeminde intravitreal Bevasizumab ve Grid Fotokoagülasyon karşılaştırılması. ( Poster) TOD 43. Ulusal Kongresi.11-15 Kasım 200