Aufbau und Inbetriebnahme eines Verbrennungsmotorprüfstandes in eine kompatible Motor-Box.

Ziel dieser Diplomarbeit ist die Dokumentation der Konstruktion, des Aufbaus sowie die Inbetriebnahme eines Prüfstandes. Bei dem Prüfobjekt handelt es sich um einen Otto-Verbrennungsmotor, und zwar um den Opel Ecotec 3 Zylinder Motor mit einem Liter Hubraum. Mithilfe dieses Prüfstandes soll die Motorfunktion unter verschiedenen Betriebsbedingungen untersucht werden

Jeavons Syndrome: 12 Cases

Objectives: Jeavons Syndrome (JS), also known as eyelid myoclonia with absences epilepsy, is a type of idiopathic reflex epilepsy that has primary seizure type eyelid myoclonuses and is characterized by blinking due to seizures or generalized paroxysms at electroencephalography (EEG) and photosensitivity. This study aimed to review JS by following up with the patients with this diagnosis

Impact of preoperative visual acuity on Descemet Membrane Endothelial Keratoplasty (DMEK) outcome

PurposeTo evaluate whether and how preoperative visual acuity predicts visual acuity outcome after Descemet Membrane Endothelial Keratoplasty (DMEK).MethodsOne thousand eighty-four out of 1162 consecutive eyes having undergone DMEK alone or combined with cataract surgery (triple-DMEK) between July 2011 and February 2016 from the prospective Cologne DMEK database were included and analyzed retrospectively for correlations between pre- and postoperative visual acuity values at 1, 3, 6, and 12months after transplantation.ResultsThere is a significant correlation between pre- and postoperative visual acuity (VA) after (triple)-DMEK after 6 and 12months (p=0.005 and p=0.011 respectively; Pearson's correlation coefficient 0.240 and 0.224). Preoperative VA below 20/100 leads to delayed and reduced final visual acuity results after 12months (p0.1 logMAR as clinically relevant, we could not show any clinically relevant significant difference in the time needed to recover to final VA and in final VA. There is no significant difference for preoperative VA values above 20/40. The chance to reach postoperative VA above 20/25 is 40% for preoperative VA of 20/200, 50% for preoperative VA of 20/60 and >60% for preoperative VA of 20/40.ConclusionDMEK results in very good final postoperative visual acuity results even in eyes with very poor preoperative vision caused by corneal pathology. However, preoperative visual acuity values below 20/100 result in significantly poorer visual recovery, which suggests that there is benefit in performing surgery early enough before this value is reached. Preoperative visual acuity seems to be an adjuvant toolfor the prediction of thefinal visual outcome after DMEK

Incidence and Clinical Course of Immune Reactions after Descemet Membrane Endothelial Keratoplasty Retrospective Analysis of 1000 Consecutive Eyes

Purpose: To analyze the incidence and clinical course of graft rejection episodes after Descemet membrane endothelial keratoplasty (DMEK). Design: Retrospective analysis of a consecutive, interventional case series. Participants: One thousand eyes that underwent DMEK from July 2011 through August 2015 at the Department of Ophthalmology, University of Cologne. Methods: All cases with follow-up of at least 1 month were included (mean follow-up, 18.5 months). Patients with a graft rejection episode were followed up for 1 additional year. Main Outcome Measures: Incidence of graft rejection, best spectacle-corrected visual acuity (BSCVA), central corneal thickness (CCT), endothelial cell density (ECD), and need for regraft. Results: Nine hundred five cases met the inclusion criteria. A graft rejection episode developed in 12 patients (estimated probability of rejection at 1 year, 0.9%; at 2 years, 2.3%; at 4 years, 2.3%). At time of rejection, 9 of 12 patients had stopped corticosteroids. Five patients were symptomatic and 7 did not note the rejection episode. Intensified topical corticosteroid therapy was started immediately after diagnosis of rejection. Two eyes decompensated and required a regraft, whereas the remaining 10 eyes required no regraft (BSCVA, 0.27 +/- 0.28 logarithm of the minimum angle of resolution [logMAR]; CCT, 554.1 +/- 39.1 mu m at last visit before rejection vs. BSCVA, 0.21 +/- 0.15 logMAR; CCT, 540.0 +/- 15.0 mu m 3 months after rejection). One year after the rejection episodes, BSCVA and CCT in these eyes remained unchanged when compared with the last visit before rejection (BSCVA, 0.15 +/- 0.11 logMAR; CCT, 533.8 +/- 26.0 mu m). Significant changes were observed for ECD values (1741 +/- 274.5 cells/mm(2) at last visit before rejection vs. 1356 +/- 380.3 cells/mm(2) after 3 months [P = 0.04] and 1290 +/- 359.0 cells/mm(2) after 1 year [P = 0.01]). Conclusions: The risk for graft rejection afterDMEK is low, and an even smaller minority requires a regraft. After intensified local corticosteroid therapy, most patients show stable visual acuity and CCT, although ECD decreases. The occurrence of immune reactions up to 2 years after surgery predominantly in patients not receiving corticosteroids supports the prolonged use of corticosteroids after DMEK. (C) 2017 by the American Academy of Ophthalmolog